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Companies / Healthcare / ACADIA PHARMACEUTICALS INC
ACAD

ACADIA PHARMACEUTICALS INC

HealthcarePharmaceutical Preparations
Ticker ACADSAN DIEGO, CAFiscal year ends DecemberBook value per share $7.56Diluted shares 172.9M

Acadia Pharmaceuticals Inc. (NASDAQ: ACAD) is a biopharmaceutical company focused on developing and commercializing innovative treatments for neurological and rare diseases. The company maintains its global headquarters in San Diego, California, with substantial operations in Princeton, New Jersey and European… From the company’s description.

Fiscal year 2025 · ends 12-31Changes are against fiscal 2024The amber dot is the latest twelve months, to 2026-06-30
Sales & profitability
$1.07B
+11.9% year over year
Last 12 mo $1.14B
9.78%
−14.3 percentage points
Last 12 mo 7.59%
$391.00M
+72.7% year over year
Last 12 mo $380.48M
31.86%
+1 percentage points
Last 12 mo 29.12%
Cash & financing
$109.84M
−30.4% year over year
Last 12 mo $160.32M
$105.15M
−33.1% year over year
Last 12 mo $145.63M
—
169.9M
+2.1% year over year
Last 12 mo 172.9M

Margins and return on equity change in ; everything else in percent. Fewer shares and less debt are shown plainly, not as bad news — it depends what you make of buybacks. Dotted labels explain each measure. is shown separately from the annual figures.

What ACADIA PHARMACEUTICALS INC does

In the company’s own words

Acadia Pharmaceuticals Inc. (NASDAQ: ACAD) is a biopharmaceutical company focused on developing and commercializing innovative treatments for neurological and rare diseases. The company maintains its global headquarters in San Diego, California, with substantial operations in Princeton, New Jersey and European headquarters in Zug, Switzerland. More information is available at www.acadia.com.

Acadia operates two core commercial franchises. The neurological disease franchise is anchored by NUPLAZID (pimavanserin), the first and only FDA-approved treatment for hallucinations and delusions associated with Parkinson's disease psychosis. The rare disease franchise centers on DAYBUE (trofinetide), the first and only approved treatment for Rett syndrome. These two commercial products generated net product sales of $1,071.5 million in 2025. DAYBUE STIX, a powder formulation for oral solution, received FDA approval in December 2025 and launched in the first quarter of 2026.

Beyond its commercial products, Acadia maintains a pipeline of product candidates addressing significant unmet medical needs. Remlifanserin (formerly ACP-204) is in Phase 2 development for Alzheimer's disease psychosis and Lewy Body Dementia psychosis. ACP-211, a deuterated R-norketamine, is in Phase 2 development for major depressive disorder. ACP-711, a GABAA-α3 positive allosteric modulator licensed from Saniona, is being developed for essential tremor with Phase 2 expected to begin in late 2026 or early 2027. ACP-271, a GPR88 agonist, is planned for Phase 1 studies in tardive dyskinesia and Huntington's disease. The company also maintains early-stage programs including ACP-2591 for Rett syndrome and Fragile X syndrome, and an antisense oligonucleotide program through collaboration with Stoke Therapeutics for SYNGAP1 syndrome.

Acadia's strategy emphasizes maximizing growth of NUPLAZID and DAYBUE in the United States while expanding trofinetide internationally, particularly in the European Union and Japan. The company is investing in four core strategic capabilities: precision medicine, data innovation through artificial intelligence and machine learning, globalization, and patient empowerment. Acadia holds approximately 49 issued U.S. patents and exclusive licenses to additional patents covering its product portfolio.

Company details
Sector
Healthcare
Industry
Pharmaceutical Preparations
Headquarters
SAN DIEGO, CA
Fiscal year end
December
CIK
1070494
SIC
2834

Financial performance, year by year

Fiscal 2013–2025 · USD
$-432.21M$-3.79M$424.62M$853.03M$1.28B2013201420152016201720182019202020212022202320242025Last 12 moLast 12 monthsLast 12 months

The full income statement, balance sheet and cash flow for each of these years — every figure traceable to its filing — is on the Financials tab with a free account.

Ownership

Who owns ACADIA PHARMACEUTICALS INC — and what changed

Funds as of 2026Q2 · superinvestors as of 2026-06-30

303
funds hold it
0 of 35
superinvestors hold it
$1.31B
held by funds, at market
31.3%
of shares held by funds

Largest fund holders · ACADIA PHARMACEUTICALS INC’s weight in each

iShares Core S&P Small-Cap ETF
IJR · iShares Trust
0.17%of fund net assets
VANGUARD TOTAL STOCK MARKET INDEX FUND
VTI · VANGUARD INDEX FUNDS
0.00%of fund net assets
0.94%of fund net assets
iShares Russell 2000 ETF
IWM · iShares Trust
0.10%of fund net assets
VANGUARD SMALL-CAP INDEX FUND
VB · VANGUARD INDEX FUNDS
0.04%of fund net assets

Fund ownership is a floor, not a census — pensions, insurers and people holding shares directly are not visible here.

Fund ownership counts N-PORT filers only, so it is a floor rather than a census — pensions, insurers and direct holders are not visible here, and the remainder is not “held by individuals”.

Every fund and institutional holder, quarter by quarter, is on the Ownership tab with a free account.

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