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Companies / Health Care / Achieve Life Sciences, Inc.
ACHV

Achieve Life Sciences, Inc.

Health CareChemicals
Ticker ACHVSEATTLE, WAFiscal year ends DecemberBook value per share $-0.20Diluted shares 73.6M

Achieve Life Sciences, Inc. (Nasdaq: ACHV) is a late-stage clinical specialty pharmaceutical company developing cytisinicline, a nicotine-dependence treatment candidate for smoking and e-cigarette cessation. The naturally occurring alkaloid is designed to reduce cravings and withdrawal symptoms and lessen nicotine’s… From the company’s description.

In fiscal 2025, Achieve Life Sciences, Inc. reported a net loss of $54.65M. Operations used $49.47M in cash.

Fiscal year 2025 · ends 12-31Changes are against fiscal 2024The amber dot is the latest twelve months, to 2026-06-30
Sales & profitability
—
0.00%FY2025
$-54.65MFY2025
−37.2% year over year
Last 12 mo $-114.04M
-253.96%FY2025
−63.4 percentage points
Last 12 mo 777.05%
Cash & financing
$-49.47MFY2025
−66.2% year over year
Last 12 mo $-47.02M
$-49.47MFY2025
−66.2% year over year
Last 12 mo $-47.02M
0.76FY2025
Was 0.53× a year earlier
Last 12 mo -1.11
43.6MFY2025
+35.9% year over year
Last 12 mo 73.6M

Margins and return on equity change in ; everything else in percent. Fewer shares and less debt are shown plainly, not as bad news — it depends what you make of buybacks. Dotted labels explain each measure. is shown separately from the annual figures.

What Achieve Life Sciences, Inc. does

In the company’s own words

Achieve Life Sciences, Inc. (Nasdaq: ACHV) is a late-stage clinical specialty pharmaceutical company developing cytisinicline, a nicotine-dependence treatment candidate for smoking and e-cigarette cessation. The naturally occurring alkaloid is designed to reduce cravings and withdrawal symptoms and lessen nicotine’s rewarding effects; it is investigational in the United States, where the company’s application for smoking cessation is under FDA review. Achieve holds an exclusive license to develop and commercialize cytisinicline outside territories served by Sopharma, which markets the Tabex brand in parts of Central and Eastern Europe and other regions. The company is also developing cytisinicline for vaping cessation, for which it has received FDA Breakthrough Therapy designation. Achieve focuses on developing and commercializing this single product candidate and reports no separate business segments. Its clinical program includes studies of six- and 12-week treatment regimens, and it has partnered with a U.S.-based manufacturer for potential commercial supply. The supplied filing text does not state a corporate website.

Company details
Sector
Health Care
Industry (SIC)
Chemicals
Headquarters
SEATTLE, WA
Fiscal year end
December
CIK
949858
SIC
2835

Financial performance, year by year

Fiscal 2011–2025 · USD
$-128.43M$-85.26M$-42.08M$1.10M$44.27M201120122013201420152016201720182019202020212022202320242025Last 12 moLast 12 months

The full income statement, balance sheet and cash flow for each of these years — every figure traceable to its filing — is on the Financials tab with a free account.

Ownership

Who owns Achieve Life Sciences, Inc. — and what changed

Funds as of 2026Q2 · superinvestors as of 2026-06-30

62
funds hold it
0 of 35
superinvestors hold it
$93.86M
held by funds, at market
14.6%
of shares held by funds

Largest fund holders · Achieve Life Sciences, Inc.’s weight in each

VANGUARD TOTAL STOCK MARKET INDEX FUND
VTI · VANGUARD INDEX FUNDS
0.00%of fund net assets
Eventide Healthcare & Life Sciences Fund
ETAHX · MUTUAL FUND SERIES TRUST
0.81%of fund net assets
iShares Russell 2000 ETF
IWM · iShares Trust
0.02%of fund net assets
Simplify Propel Opportunities ETF
SURI · Simplify Exchange Traded Funds
12.11%of fund net assets
0.08%of fund net assets

Fund ownership is a floor, not a census — pensions, insurers and people holding shares directly are not visible here.

Fund ownership counts N-PORT filers only, so it is a floor rather than a census — pensions, insurers and direct holders are not visible here, and the remainder is not “held by individuals”.

Every fund and institutional holder, quarter by quarter, is on the Ownership tab with a free account.

Connected research

Put this business in context.

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  • “How do Achieve Life Sciences, Inc. and its peers compare on margins and cash generation over ten years?”
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