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Companies / Health Care / Arcus Biosciences, Inc.
RCUS

Arcus Biosciences, Inc.

Health CarePharmaceutical Preparations
Ticker RCUSHAYWARD, CAFiscal year ends DecemberBook value per share $2.83Diluted shares 126.3M

Arcus Biosciences, Inc. (NYSE: RCUS) is a clinical-stage biopharmaceutical company developing medicines for cancer and inflammatory and autoimmune diseases. Its oncology pipeline includes casdatifan, a small-molecule HIF-2α inhibitor; quemliclustat, a CD73 inhibitor; domvanalimab, an anti-TIGIT antibody; and… From the company’s description.

Over the twelve months to Sep 30, 2026, Arcus Biosciences, Inc. reported revenue of $100.00M, down 58.3% from a year earlier, and a net loss of $453.00M. Its operating margin was −475.0%, and operations used $465.00M in cash. In fiscal 2025, it reported revenue of $247.00M, down 4.3% from fiscal 2024, and a net loss of $353.00M.

Fiscal year 2025 · ends 12-31Changes are against fiscal 2024The amber dot is the latest twelve months, to 2026-09-30
Sales & profitability
$247.00MFY2025
−4.3% year over year
Last 12 mo $100.00M
-156.28%FY2025
−28.4 percentage points
Last 12 mo -475.00%
$-353.00MFY2025
−24.7% year over year
Last 12 mo $-453.00M
-55.94%FY2025
−1.7 percentage points
Last 12 mo -126.54%
Cash & financing
$-482.00MFY2025
−183.5% year over year
Last 12 mo $-465.00M
$-484.00MFY2025
−175.0% year over year
Last 12 mo $-466.00M
0.16FY2025
Was 0.10× a year earlier
Last 12 mo 0.28
107.4MFY2025
+19.2% year over year
Last 12 mo 126.3M

Margins and return on equity change in ; everything else in percent. Fewer shares and less debt are shown plainly, not as bad news — it depends what you make of buybacks. Dotted labels explain each measure. is shown separately from the annual figures.

What Arcus Biosciences, Inc. does

In the company’s own words

Arcus Biosciences, Inc. (NYSE: RCUS) is a clinical-stage biopharmaceutical company developing medicines for cancer and inflammatory and autoimmune diseases. Its oncology pipeline includes casdatifan, a small-molecule HIF-2α inhibitor; quemliclustat, a CD73 inhibitor; domvanalimab, an anti-TIGIT antibody; and zimberelimab, an anti-PD-1 antibody. The company is also advancing small-molecule programs in inflammation, including research targeting MRGPRX2, TNF, CCR6, CD89 and CD40 ligand, with a focus on oral therapies. Arcus has no reportable business segments described here; it works with Gilead Sciences on development and commercialization of certain oncology programs and has licensed regional rights to Taiho Pharmaceutical. Its most advanced molecules are in Phase 3 studies, including casdatifan for renal cell carcinoma and quemliclustat for metastatic pancreatic cancer. Arcus reports no product sales and relies on third parties to manufacture its investigational medicines. Its website is www.arcusbio.com.

Company details
Sector
Health Care
Industry (SIC)
Pharmaceutical Preparations
Headquarters
HAYWARD, CA
Fiscal year end
December
CIK
1724521
SIC
2834

Financial performance, year by year

Fiscal 2018–2025 · USD
$-536.59M$-285.82M$-35.06M$215.71M$466.47M20182019202020212022202320242025Last 12 moLast 12 monthsLast 12 months

The full income statement, balance sheet and cash flow for each of these years — every figure traceable to its filing — is on the Financials tab with a free account.

Ownership

Who owns Arcus Biosciences, Inc. — and what changed

Funds as of 2026Q2 · superinvestors as of 2026-06-30

260
funds hold it
0 of 35
superinvestors hold it
$1.07B
held by funds, at market
25.8%
of shares held by funds

Largest fund holders · Arcus Biosciences, Inc.’s weight in each

iShares Core S&P Small-Cap ETF
IJR · iShares Trust
0.14%of fund net assets
VANGUARD HEALTH CARE FUND
VGHCX · VANGUARD SPECIALIZED FUNDS
—of fund net assets
VANGUARD TOTAL STOCK MARKET INDEX FUND
VTI · VANGUARD INDEX FUNDS
0.00%of fund net assets
0.74%of fund net assets
iShares Russell 2000 ETF
IWM · iShares Trust
0.09%of fund net assets

Fund ownership is a floor, not a census — pensions, insurers and people holding shares directly are not visible here.

Fund ownership counts N-PORT filers only, so it is a floor rather than a census — pensions, insurers and direct holders are not visible here, and the remainder is not “held by individuals”.

Could not be determined for this company: bond issues.

Every fund and institutional holder, quarter by quarter, is on the Ownership tab with a free account.

Connected research

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