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Companies / Health Care / Cabaletta Bio, Inc.
CABA

Cabaletta Bio, Inc.

Health CareBiological Products
Ticker CABAPHILADELPHIA, PAFiscal year ends DecemberBook value per share $1.89Diluted shares 150.3M

Cabaletta Bio (Nasdaq: CABA) is a clinical-stage biotechnology company developing engineered T cell therapies for autoimmune diseases. Its CABA® platform uses chimeric antigen receptor T cells for autoimmunity, with lead candidate resecabtagene autoleucel (rese-cel), a CD19-directed CAR T therapy designed to deplete B… From the company’s description.

In fiscal 2025, Cabaletta Bio, Inc. reported a net loss of $167.86M. Operations used $131.08M in cash.

Fiscal year 2025 · ends 12-31Changes are against fiscal 2024The amber dot is the latest twelve months, to 2026-09-30
Sales & profitability
—
0.00%FY2025
$-167.86MFY2025
−44.9% year over year
Last 12 mo $-189.50M
-149.80%FY2025
−73.7 percentage points
Last 12 mo -66.75%
Cash & financing
$-131.08MFY2025
−48.6% year over year
Last 12 mo $-162.16M
$-132.31MFY2025
−46.3% year over year
Last 12 mo $-162.51M
0.21FY2025
Was 0.06× a year earlier
Last 12 mo 0.06
79.9MFY2025
+61.4% year over year
Last 12 mo 150.3M

Margins and return on equity change in ; everything else in percent. Fewer shares and less debt are shown plainly, not as bad news — it depends what you make of buybacks. Dotted labels explain each measure. is shown separately from the annual figures.

What Cabaletta Bio, Inc. does

In the company’s own words

Cabaletta Bio (Nasdaq: CABA) is a clinical-stage biotechnology company developing engineered T cell therapies for autoimmune diseases. Its CABA® platform uses chimeric antigen receptor T cells for autoimmunity, with lead candidate resecabtagene autoleucel (rese-cel), a CD19-directed CAR T therapy designed to deplete B cells and potentially reset the immune system after a single infusion. Cabaletta is evaluating rese-cel in clinical trials for systemic lupus erythematosus, myositis, systemic sclerosis, generalized myasthenia gravis and pemphigus vulgaris, including trials assessing use without preconditioning; it initiated a registrational myositis trial in December 2025. The company’s development portfolio also includes a legacy engineered cell therapy program, while its current clinical focus is rese-cel. Cabaletta relies on external manufacturing partners, including Minaris, Lonza and Cellares, for clinical supply and is developing processes intended to support later-stage trials and potential commercial production. Founded in 2017, the company grew from research combining expertise in B cell-mediated autoimmune disease and CAR T cell design. Its website is https://cabalettabio.com.

Company details
Sector
Health Care
Industry (SIC)
Biological Products
Headquarters
PHILADELPHIA, PA
Fiscal year end
December
CIK
1759138
SIC
2836

Financial performance, year by year

Fiscal 2019–2025 · USD
$-206.76M$-154.99M$-103.22M$-51.46M$0.31M2019202020212022202320242025Last 12 moLast 12 months

The full income statement, balance sheet and cash flow for each of these years — every figure traceable to its filing — is on the Financials tab with a free account.

Ownership

Who owns Cabaletta Bio, Inc. — and what changed

Funds as of 2026Q2 · superinvestors as of 2026-06-30

114
funds hold it
0 of 35
superinvestors hold it
$141.25M
held by funds, at market
20.4%
of shares held by funds

Largest fund holders · Cabaletta Bio, Inc.’s weight in each

T. Rowe Price Small-Cap Value Fund, Inc.
PRSVX · T. ROWE PRICE SMALL-CAP VALUE FUND, INC.
0.23%of fund net assets
PGIM Jennison Health Sciences Fund
PHLAX · Prudential Sector Funds, Inc.
—of fund net assets
0.15%of fund net assets
VANGUARD TOTAL STOCK MARKET INDEX FUND
VTI · VANGUARD INDEX FUNDS
0.00%of fund net assets
iShares Russell 2000 ETF
IWM · iShares Trust
0.01%of fund net assets

Fund ownership is a floor, not a census — pensions, insurers and people holding shares directly are not visible here.

Fund ownership counts N-PORT filers only, so it is a floor rather than a census — pensions, insurers and direct holders are not visible here, and the remainder is not “held by individuals”.

Could not be determined for this company: bond issues.

Every fund and institutional holder, quarter by quarter, is on the Ownership tab with a free account.

Connected research

Put this business in context.

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