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Companies / Health Care / Candel Therapeutics, Inc.
CADL

Candel Therapeutics, Inc.

Health CareBiological Products
Ticker CADLNEEDHAM, MAFiscal year ends DecemberBook value per share $1.85Diluted shares 68.3M

Candel Therapeutics, Inc. (Nasdaq: CADL) is a clinical-stage biopharmaceutical company developing off-the-shelf viral immunotherapies intended to stimulate local and systemic anti-tumor immune responses. Its candidates are administered directly into tumors and are designed to prompt tumor-cell destruction and immune… From the company’s description.

In fiscal 2025, Candel Therapeutics, Inc. reported a net loss of $38.18M. Operations used $38.31M in cash.

Fiscal year 2025 · ends 12-31Changes are against fiscal 2024The amber dot is the latest twelve months, to 2026-06-30
Sales & profitability
—
0.00%FY2025
$-38.18MFY2025
+30.8% year over year
Last 12 mo $-88.53M
-73.54%FY2025
+9.7 percentage points
Last 12 mo -70.19%
Cash & financing
$-38.31MFY2025
−41.8% year over year
Last 12 mo $-56.02M
$-38.90MFY2025
−43.9% year over year
Last 12 mo $-57.32M
0.91FY2025
Was 0.19× a year earlier
Last 12 mo 0.38
53.0MFY2025
+67.2% year over year
Last 12 mo 68.3M

Margins and return on equity change in ; everything else in percent. Fewer shares and less debt are shown plainly, not as bad news — it depends what you make of buybacks. Dotted labels explain each measure. is shown separately from the annual figures.

What Candel Therapeutics, Inc. does

In the company’s own words

Candel Therapeutics, Inc. (Nasdaq: CADL) is a clinical-stage biopharmaceutical company developing off-the-shelf viral immunotherapies intended to stimulate local and systemic anti-tumor immune responses. Its candidates are administered directly into tumors and are designed to prompt tumor-cell destruction and immune activity against injected and distant tumors. The company’s two clinical platforms use genetically modified adenoviruses and herpes simplex viruses (HSV). Its lead candidate, aglatimagene besadenovec, is an adenovirus therapy studied with valacyclovir and other treatments across prostate cancer, non-small cell lung cancer and pancreatic cancer; linoserpaturev, an HSV-based candidate, is being studied for recurrent high-grade glioma. The enLIGHTEN Discovery Platform supports the design of additional HSV-based candidates, including preclinical programs for solid tumors. Candel conducts research and development across these programs and relies on third-party manufacturers for commercial-scale production. The company was incorporated as Advantagene in 2003, licensed Periphagen assets in 2019 and linoserpaturev in 2020, and adopted the Candel Therapeutics name in December 2020. Its website is https://www.candeltx.com/.

Company details
Sector
Health Care
Industry (SIC)
Biological Products
Headquarters
NEEDHAM, MA
Fiscal year end
December
CIK
1841387
SIC
2836

Financial performance, year by year

Fiscal 2021–2025 · USD
$-97.40M$-70.80M$-44.20M$-17.61M$8.99M20212022202320242025Last 12 moLast 12 months

The full income statement, balance sheet and cash flow for each of these years — every figure traceable to its filing — is on the Financials tab with a free account.

Ownership

Who owns Candel Therapeutics, Inc. — and what changed

Funds as of 2026Q2 · superinvestors as of 2026-06-30

112
funds hold it
0 of 35
superinvestors hold it
$182.76M
held by funds, at market
26.3%
of shares held by funds

Largest fund holders · Candel Therapeutics, Inc.’s weight in each

Select Biotechnology Portfolio
FBIOX · Fidelity Select Portfolios
—of fund net assets
0.19%of fund net assets
VANGUARD TOTAL STOCK MARKET INDEX FUND
VTI · VANGUARD INDEX FUNDS
0.00%of fund net assets
Fidelity Growth Company Fund
FDGRX · Fidelity Mt. Vernon Street Trust
—of fund net assets
iShares Russell 2000 ETF
IWM · iShares Trust
0.02%of fund net assets

Fund ownership is a floor, not a census — pensions, insurers and people holding shares directly are not visible here.

Fund ownership counts N-PORT filers only, so it is a floor rather than a census — pensions, insurers and direct holders are not visible here, and the remainder is not “held by individuals”.

Could not be determined for this company: bond issues.

Every fund and institutional holder, quarter by quarter, is on the Ownership tab with a free account.

Connected research

Put this business in context.

Compare this company with peers, find it in your funds and follow its financial history with your connected AI:

  • “How do Candel Therapeutics, Inc. and its peers compare on margins and cash generation over ten years?”
  • “Where did five years of Candel Therapeutics, Inc.'s earnings go — cash, debt, buybacks, reinvestment?”
  • “What changed in Candel Therapeutics, Inc.'s last four quarterly filings that the numbers alone won't show?”
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