10x Insights
Loading account…
Companies / Health Care / Cogent Biosciences, Inc.
COGT

Cogent Biosciences, Inc.

Health CarePharmaceutical Preparations
Ticker COGTWALTHAM, MAFiscal year ends DecemberBook value per share $3.20Diluted shares 166.6M

Cogent Biosciences, Inc. (Nasdaq: COGT) is a clinical-stage biotechnology company developing precision therapies for genetically defined diseases. Its lead candidate, bezuclastinib, is a selective KIT inhibitor being developed for systemic mastocytosis and gastrointestinal stromal tumors; the company is also advancing… From the company’s description.

In fiscal 2025, Cogent Biosciences, Inc. reported a net loss of $328.94M. Operations used $264.44M in cash.

Fiscal year 2025 · ends 12-31Changes are against fiscal 2024The amber dot is the latest twelve months, to 2026-06-30
Sales & profitability
—
0.00%FY2025
$-328.94MFY2025
−28.6% year over year
Last 12 mo $-377.18M
-51.69%FY2025
+48.1 percentage points
Last 12 mo -70.85%
Cash & financing
$-264.44MFY2025
−27.3% year over year
Last 12 mo $-307.55M
$-266.00MFY2025
−27.7% year over year
Last 12 mo $-309.24M
0.35FY2025
Last 12 mo 0.42
128.9MFY2025
+24.1% year over year
Last 12 mo 166.6M

Margins and return on equity change in ; everything else in percent. Fewer shares and less debt are shown plainly, not as bad news — it depends what you make of buybacks. Dotted labels explain each measure. is shown separately from the annual figures.

What Cogent Biosciences, Inc. does

In the company’s own words

Cogent Biosciences, Inc. (Nasdaq: COGT) is a clinical-stage biotechnology company developing precision therapies for genetically defined diseases. Its lead candidate, bezuclastinib, is a selective KIT inhibitor being developed for systemic mastocytosis and gastrointestinal stromal tumors; the company is also advancing programs targeting FGFR2/3, mutant ErbB2, PI3Kα, KRAS and JAK2. Its potential customers are patients with these diseases and, if its candidates receive approval, healthcare providers and payors. Cogent is developing an internal commercial organization to support a potential U.S. launch of bezuclastinib. The company’s pipeline includes CGT4859, an FGFR2/3 inhibitor in Phase 1; CGT4255, a mutant ErbB2 inhibitor in Phase 1; and additional clinical and preclinical programs. Cogent licenses worldwide development and commercialization rights for bezuclastinib from Plexxikon and relies on third parties to manufacture its drug candidates. Its website is https://cogentbio.com.

Company details
Sector
Health Care
Industry (SIC)
Pharmaceutical Preparations
Headquarters
WALTHAM, MA
Fiscal year end
December
CIK
1622229
SIC
2834

Financial performance, year by year

Fiscal 2018–2025 · USD
$-417.15M$-297.24M$-177.34M$-57.44M$62.47M20182019202020212022202320242025Last 12 moLast 12 months

The full income statement, balance sheet and cash flow for each of these years — every figure traceable to its filing — is on the Financials tab with a free account.

Ownership

Who owns Cogent Biosciences, Inc. — and what changed

Funds as of 2026Q2 · superinvestors as of 2026-06-30

352
funds hold it
0 of 35
superinvestors hold it
$2.79B
held by funds, at market
43.2%
of shares held by funds

Largest fund holders · Cogent Biosciences, Inc.’s weight in each

VANGUARD TOTAL STOCK MARKET INDEX FUND
VTI · VANGUARD INDEX FUNDS
0.01%of fund net assets
iShares Russell 2000 ETF
IWM · iShares Trust
0.20%of fund net assets
VANGUARD SMALL-CAP INDEX FUND
VB · VANGUARD INDEX FUNDS
0.08%of fund net assets
1.14%of fund net assets
VANGUARD SMALL-CAP VALUE INDEX FUND
VBR · VANGUARD INDEX FUNDS
0.13%of fund net assets

Fund ownership is a floor, not a census — pensions, insurers and people holding shares directly are not visible here.

Fund ownership counts N-PORT filers only, so it is a floor rather than a census — pensions, insurers and direct holders are not visible here, and the remainder is not “held by individuals”.

Could not be determined for this company: bond issues.

Every fund and institutional holder, quarter by quarter, is on the Ownership tab with a free account.

Connected research

Put this business in context.

Compare this company with peers, find it in your funds and follow its financial history with your connected AI:

  • “How do Cogent Biosciences, Inc. and its peers compare on margins and cash generation over ten years?”
  • “Where did five years of Cogent Biosciences, Inc.'s earnings go — cash, debt, buybacks, reinvestment?”
  • “What changed in Cogent Biosciences, Inc.'s last four quarterly filings that the numbers alone won't show?”
See how it works →All research tools with a subscription. Use your own AI account.