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Companies / Health Care / Cytokinetics, Incorporated
CYTK

Cytokinetics, Incorporated

Health CarePharmaceutical Preparations
Ticker CYTKSOUTH SAN FRANCISCO, CAFiscal year ends DecemberBook value per share $-1.36Diluted shares 127.7M

Cytokinetics, Incorporated (Nasdaq: CYTK) is a biopharmaceutical company that discovers, develops and commercializes small-molecule medicines targeting muscle function for cardiovascular and neuromuscular diseases. Its first commercial product, MYQORZO (aficamten), is an oral cardiac myosin inhibitor approved in the… From the company’s description.

In fiscal 2025, Cytokinetics, Incorporated reported revenue of $88.04M, up 376.6% from fiscal 2024, and a net loss of $784.96M. Its operating margin was −695.4%, and operations used $510.01M in cash. Over the twelve months to Jun 30, 2026, revenue was $67.67M.

Fiscal year 2025 · ends 12-31Changes are against fiscal 2024The amber dot is the latest twelve months, to 2026-06-30
Sales & profitability
$88.04MFY2025
+376.6% year over year
Last 12 mo $67.67M
-695.44%FY2025
+2207.3 percentage points
Last 12 mo -1046.12%
$-784.96MFY2025
−33.2% year over year
Last 12 mo $-894.00M
119.00%FY2025
−316.5 percentage points
Last 12 mo 515.31%
Cash & financing
$-510.01MFY2025
−28.8% year over year
Last 12 mo $-555.45M
$-534.82MFY2025
−33.8% year over year
Last 12 mo $-580.71M
-1.75FY2025
Was -4.85× a year earlier
Last 12 mo -6.61
120.1MFY2025
+7.3% year over year
Last 12 mo 127.7M

Margins and return on equity change in ; everything else in percent. Fewer shares and less debt are shown plainly, not as bad news — it depends what you make of buybacks. Dotted labels explain each measure. is shown separately from the annual figures.

What Cytokinetics, Incorporated does

In the company’s own words

Cytokinetics, Incorporated (Nasdaq: CYTK) is a biopharmaceutical company that discovers, develops and commercializes small-molecule medicines targeting muscle function for cardiovascular and neuromuscular diseases. Its first commercial product, MYQORZO (aficamten), is an oral cardiac myosin inhibitor approved in the United States, European Union and China for adults with symptomatic obstructive hypertrophic cardiomyopathy; customers include patients and the specialist cardiologists who diagnose and treat the condition. The company is also developing aficamten for non-obstructive HCM, omecamtiv mecarbil, a cardiac myosin activator for heart failure with reduced ejection fraction, ulacamten for a subset of patients with heart failure with preserved ejection fraction, and CK-089 for muscular dystrophy and other conditions involving impaired muscle function. Cytokinetics operates as an integrated specialty biopharmaceutical business, combining research and development with commercialization; it uses licensing partners for aficamten in China and Japan and relies on third parties for manufacturing. In 2025, it received FDA approval for MYQORZO and began U.S. commercial sales in early 2026. Its website is www.cytokinetics.com.

Company details
Sector
Health Care
Industry (SIC)
Pharmaceutical Preparations
Headquarters
SOUTH SAN FRANCISCO, CA
Fiscal year end
December
CIK
1061983
SIC
2834

Financial performance, year by year

Fiscal 2013–2025 · USD
$-994.04M$-693.92M$-393.80M$-93.67M$206.45M2013201420152016201720182019202020212022202320242025Last 12 moLast 12 monthsLast 12 months

The full income statement, balance sheet and cash flow for each of these years — every figure traceable to its filing — is on the Financials tab with a free account.

Ownership

Who owns Cytokinetics, Incorporated — and what changed

Funds as of 2026Q2 · superinvestors as of 2026-06-30

504
funds hold it
0 of 35
superinvestors hold it
$6.23B
held by funds, at market
55.9%
of shares held by funds
2
bond issues held by funds

Largest fund holders · Cytokinetics, Incorporated’s weight in each

T. Rowe Price Capital Appreciation Fund
PRWCX · T. ROWE PRICE CAPITAL APPRECIATION FUND, INC.
0.76%of fund net assets
iShares Core S&P Mid-Cap ETF
IJH · iShares Trust
0.32%of fund net assets
VANGUARD TOTAL STOCK MARKET INDEX FUND
VTI · VANGUARD INDEX FUNDS
0.02%of fund net assets
iShares Russell 2000 ETF
IWM · iShares Trust
0.35%of fund net assets
VANGUARD SMALL-CAP INDEX FUND
VB · VANGUARD INDEX FUNDS
0.14%of fund net assets

Fund ownership is a floor, not a census — pensions, insurers and people holding shares directly are not visible here.

Cytokinetics, Incorporated’s bonds, as funds hold them

Funds report holding 2 issues of Cytokinetics, Incorporated’s debt, $117.89M at market value — what funds hold, not the company’s total debt. Weighted-average coupon 1.87%, maturing 2027 to 2031.

Fund ownership counts N-PORT filers only, so it is a floor rather than a census — pensions, insurers and direct holders are not visible here, and the remainder is not “held by individuals”.

Every fund and institutional holder, quarter by quarter, is on the Ownership tab with a free account.

Connected research

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