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Companies / Health Care / Exelixis, Inc.
EXEL

Exelixis, Inc.

Health CareBiological Products
Ticker EXELALAMEDA, CAFiscal year ends JanuaryBook value per share $7.00Diluted shares 263.5M

Exelixis, Inc. (Nasdaq: EXEL) is an oncology company that discovers, develops and commercializes medicines and regimens for cancer care. Its marketed products include CABOMETYX and COMETRIQ, formulations of cabozantinib used to treat several cancers, including renal cell carcinoma, hepatocellular carcinoma and thyroid… From the company’s description.

In fiscal 2026, Exelixis, Inc. reported revenue of $2.32B, up 7.0% from fiscal 2025, and net income of $782.57M. Its operating margin was 37.6%, and operations generated $884.27M in cash. Over the twelve months to Jul 3, 2026, revenue was $2.44B.

Fiscal year 2026 · ends 01-01Changes are against fiscal 2025The amber dot is the latest twelve months, to 2026-07-03
Sales & profitability
$2.32BFY2026
+7.0% year over year
Last 12 mo $2.44B
37.59%FY2026
+9.7 percentage points
Last 12 mo 39.88%
$782.57MFY2026
+50.1% year over year
Last 12 mo $860.62M
37.00%FY2026
+10.9 percentage points
Last 12 mo 46.68%
Cash & financing
$884.27MFY2026
+26.3% year over year
Last 12 mo $1.18B
$875.84MFY2026
+30.4% year over year
Last 12 mo $1.17B
—
281.9MFY2026
−4.8% year over year
Last 12 mo 263.5M

Margins and return on equity change in ; everything else in percent. Fewer shares and less debt are shown plainly, not as bad news — it depends what you make of buybacks. Dotted labels explain each measure. is shown separately from the annual figures.

What Exelixis, Inc. does

In the company’s own words

Exelixis, Inc. (Nasdaq: EXEL) is an oncology company that discovers, develops and commercializes medicines and regimens for cancer care. Its marketed products include CABOMETYX and COMETRIQ, formulations of cabozantinib used to treat several cancers, including renal cell carcinoma, hepatocellular carcinoma and thyroid cancers; COTELLIC (cobimetinib), marketed with Genentech for certain advanced melanomas; and MINNEBRO (esaxerenone), licensed to Daiichi Sankyo for hypertension in Japan. Exelixis commercializes cabozantinib in the United States and relies on Ipsen for markets outside the United States and Japan and Takeda for Japan. Its research and development pipeline includes zanzalintinib, a kinase inhibitor being studied across multiple cancer types, and small-molecule and biotherapeutic candidates, including antibody-drug conjugates and a bispecific antibody. The company reports one operating segment. In fiscal 2025, it generated $2.12 billion in net product revenue from CABOMETYX and COMETRIQ sales. Its website is www.exelixis.com.

Company details
Sector
Health Care
Industry (SIC)
Biological Products
Headquarters
ALAMEDA, CA
Fiscal year end
January
CIK
939767
SIC
2836

Financial performance, year by year

Fiscal 2011–2026 · USD
$-406.00M$369.07M$1.14B$1.92B$2.69B201120122016201620172018202020212022202320252026Last 12 moLast 12 monthsLast 12 months

The full income statement, balance sheet and cash flow for each of these years — every figure traceable to its filing — is on the Financials tab with a free account.

Ownership

Who owns Exelixis, Inc. — and what changed

Funds as of 2026Q2 · superinvestors as of 2026-06-30

607
funds hold it
0 of 35
superinvestors hold it
$5.32B
held by funds, at market
41.5%
of shares held by funds

Largest fund holders · Exelixis, Inc.’s weight in each

iShares Core S&P Mid-Cap ETF
IJH · iShares Trust
0.38%of fund net assets
VANGUARD TOTAL STOCK MARKET INDEX FUND
VTI · VANGUARD INDEX FUNDS
0.02%of fund net assets
FULLERTHALER BEHAVIORAL SMALL CAP EQUITY
FTHNX · Capitol Series Trust
3.03%of fund net assets
VANGUARD SMALL-CAP INDEX FUND
VB · VANGUARD INDEX FUNDS
0.16%of fund net assets
VANGUARD SMALL-CAP GROWTH INDEX FUND
VBK · VANGUARD INDEX FUNDS
0.37%of fund net assets

Fund ownership is a floor, not a census — pensions, insurers and people holding shares directly are not visible here.

Fund ownership counts N-PORT filers only, so it is a floor rather than a census — pensions, insurers and direct holders are not visible here, and the remainder is not “held by individuals”.

Every fund and institutional holder, quarter by quarter, is on the Ownership tab with a free account.

Connected research

Put this business in context.

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