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Companies / Health Care / Harmony Biosciences Holdings, Inc.
HRMY

Harmony Biosciences Holdings, Inc.

Health CarePharmaceutical Preparations
Ticker HRMYPLYMOUTH MEETING, PAFiscal year ends DecemberBook value per share $18.09Diluted shares 59.3M

Harmony Biosciences Holdings, Inc. (Nasdaq: HRMY) is a biopharmaceutical company developing and commercializing treatments for neurological diseases, with a focus on sleep and wake disorders, rare epilepsy, and neurobehavioral conditions. Its commercial product, WAKIX (pitolisant), is approved in the United States for… From the company’s description.

Over the twelve months to Sep 30, 2026, Harmony Biosciences Holdings, Inc. reported revenue of $989.36M, up 19.8% from a year earlier, and net income of $178.60M. Its operating margin was 22.2%, and operations generated $323.04M in cash. In fiscal 2025, it reported revenue of $868.45M, up 21.5% from fiscal 2024, and net income of $158.69M.

Fiscal year 2025 · ends 12-31Changes are against fiscal 2024The amber dot is the latest twelve months, to 2026-09-30
Sales & profitability
$868.45MFY2025
+21.5% year over year
Last 12 mo $989.36M
24.00%FY2025
−2.7 percentage points
Last 12 mo 22.17%
$158.69MFY2025
+9.1% year over year
Last 12 mo $178.60M
18.24%FY2025
−3.8 percentage points
Last 12 mo 16.66%
Cash & financing
$348.20MFY2025
+58.4% year over year
Last 12 mo $323.04M
$347.89MFY2025
+59.1% year over year
Last 12 mo $323.04M
0.19FY2025
Was 0.27× a year earlier
Last 12 mo 0.14
58.5MFY2025
+1.2% year over year
Last 12 mo 59.3M

Margins and return on equity change in ; everything else in percent. Fewer shares and less debt are shown plainly, not as bad news — it depends what you make of buybacks. Dotted labels explain each measure. is shown separately from the annual figures.

What Harmony Biosciences Holdings, Inc. does

In the company’s own words

Harmony Biosciences Holdings, Inc. (Nasdaq: HRMY) is a biopharmaceutical company developing and commercializing treatments for neurological diseases, with a focus on sleep and wake disorders, rare epilepsy, and neurobehavioral conditions. Its commercial product, WAKIX (pitolisant), is approved in the United States for excessive daytime sleepiness and cataplexy in adults and children six years and older with narcolepsy; the company reported $868.5 million in WAKIX net product revenue for 2025. Its development programs include pitolisant for idiopathic hypersomnia, Prader-Willi syndrome and myotonic dystrophy type 1, next-generation pitolisant formulations, and candidates for narcolepsy and rare epilepsy, including EPX-100 for Dravet syndrome and Lennox-Gastaut syndrome. Harmony operates through its wholly owned subsidiaries and organizes its portfolio around sleep/wake, rare epilepsy and neurobehavioral franchises. It licenses pitolisant from Bioprojet and acquired Epygenix Therapeutics to add its epilepsy programs. Its website is https://www.harmonybiosciences.com.

Company details
Sector
Health Care
Industry (SIC)
Pharmaceutical Preparations
Headquarters
PLYMOUTH MEETING, PA
Fiscal year end
December
CIK
1802665
SIC
2834

Financial performance, year by year

Fiscal 2020–2025 · USD
$-139.57M$168.32M$476.21M$784.10M$1.09B202020212022202320242025Last 12 moLast 12 monthsLast 12 months

The full income statement, balance sheet and cash flow for each of these years — every figure traceable to its filing — is on the Financials tab with a free account.

Ownership

Who owns Harmony Biosciences Holdings, Inc. — and what changed

Funds as of 2026Q2 · superinvestors as of 2026-06-30

319
funds hold it
0 of 35
superinvestors hold it
$803.96M
held by funds, at market
40.1%
of shares held by funds

Largest fund holders · Harmony Biosciences Holdings, Inc.’s weight in each

iShares Core S&P Small-Cap ETF
IJR · iShares Trust
0.08%of fund net assets
Avantis U.S. Small Cap Value ETF
AVUV · American Century ETF Trust
—of fund net assets
VANGUARD TOTAL STOCK MARKET INDEX FUND
VTI · VANGUARD INDEX FUNDS
0.00%of fund net assets
iShares Russell 2000 ETF
IWM · iShares Trust
0.05%of fund net assets
VANGUARD SMALL-CAP INDEX FUND
VB · VANGUARD INDEX FUNDS
0.02%of fund net assets

Fund ownership is a floor, not a census — pensions, insurers and people holding shares directly are not visible here.

Fund ownership counts N-PORT filers only, so it is a floor rather than a census — pensions, insurers and direct holders are not visible here, and the remainder is not “held by individuals”.

Could not be determined for this company: bond issues.

Every fund and institutional holder, quarter by quarter, is on the Ownership tab with a free account.

Connected research

Put this business in context.

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