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Companies / Healthcare / Immuneering Corp
IMRX

Immuneering Corp

HealthcarePharmaceutical Preparations
Ticker IMRXCAMBRIDGE, MAFiscal year ends DecemberBook value per share $2.95Diluted shares 64.7M

Immuneering Corporation (Nasdaq: IMRX) is a late-stage clinical oncology company focused on developing and commercializing an entirely new category of anti-cancer medicines called Deep Cyclic Inhibitors. The company's website is www.immuneering.com. From the company’s description.

Fiscal year 2025 · ends 12-31Changes are against fiscal 2024The amber dot is the latest twelve months, to 2026-06-30
Sales & profitability
—
0.00%
$-56.02M
+8.2% year over year
Last 12 mo $-57.28M
-25.64%
+121.8 percentage points
Last 12 mo -30.02%
Cash & financing
$-45.34M
+17.6% year over year
Last 12 mo $-56.75M
$-45.49M
+17.4% year over year
Last 12 mo $-56.99M
—
44.0M
+46.8% year over year
Last 12 mo 64.7M

Margins and return on equity change in ; everything else in percent. Fewer shares and less debt are shown plainly, not as bad news — it depends what you make of buybacks. Dotted labels explain each measure. is shown separately from the annual figures.

What Immuneering Corp does

In the company’s own words

Immuneering Corporation (Nasdaq: IMRX) is a late-stage clinical oncology company focused on developing and commercializing an entirely new category of anti-cancer medicines called Deep Cyclic Inhibitors. The company's website is www.immuneering.com.

Founded in 2008, Immuneering leverages translational bioinformatics and proprietary 3D tumor modeling to discover and develop novel small molecule drug programs. The company's platform analyzes high-throughput molecular-level biochemical assays, including transcriptomics, genomics, and proteomics data, combined with in vitro studies using humanized 3D tumor growth assays designed to predict in vivo activity more accurately than traditional cell culture models.

The company's lead product candidate is atebimetinib (IMM-1-104), an oral, once-daily Deep Cyclic Inhibitor of mitogen-activated protein kinase kinase (MEK) designed to improve durability and tolerability across multiple cancer indications, particularly MAPK pathway-driven tumors such as pancreatic cancer. Atebimetinib is currently in Phase 1/2a clinical trials and is expected to enter a Phase 3 registrational trial (MAPKeeper 301) in mid-2026 evaluating the drug in combination with modified gemcitabine/nab-paclitaxel in first-line pancreatic cancer patients. The FDA has granted Fast Track designation for atebimetinib in multiple indications and orphan drug designation for pancreatic cancer treatment.

Immuneering's pipeline also includes envometinib (IMM-6-415), an allosteric MEK inhibitor in Phase 1/2a development, and additional early-stage discovery programs targeting core cancer signaling pathways outside the MAPK pathway. The company's differentiated approach aims to cyclically disrupt abnormal pathway activation while sparing healthy cells, contrasting with traditional targeted therapies that chronically suppress pathways and often result in toxicity and adaptive resistance.

The company has established clinical supply agreements with Regeneron Pharmaceuticals for Libtayo (cemiplimab) and with Eli Lilly for olomorasib to support combination therapy trials in lung cancer patients. Immuneering's multidisciplinary research and development team brings expertise from leading pharmaceutical and biotechnology companies including Johnson & Johnson, Merck, Regeneron, AstraZeneca, and Novartis.

Company details
Sector
Healthcare
Industry
Pharmaceutical Preparations
Headquarters
CAMBRIDGE, MA
Fiscal year end
December
CIK
1790340
SIC
2834

Financial performance, year by year

Fiscal 2021–2025 · USD
$-67.35M$-48.41M$-29.48M$-10.54M$8.39M20212022202320242025Last 12 moLast 12 months

The full income statement, balance sheet and cash flow for each of these years — every figure traceable to its filing — is on the Financials tab with a free account.

Ownership

Who owns Immuneering Corp — and what changed

Funds as of 2026Q2 · superinvestors as of 2026-06-30

71
funds hold it
0 of 35
superinvestors hold it
$69.69M
held by funds, at market
20.1%
of shares held by funds

Largest fund holders · Immuneering Corp’s weight in each

Fidelity Growth Company Fund
FDGRX · Fidelity Mt. Vernon Street Trust
0.02%of fund net assets
VANGUARD TOTAL STOCK MARKET INDEX FUND
VTI · VANGUARD INDEX FUNDS
0.00%of fund net assets
iShares Russell 2000 ETF
IWM · iShares Trust
0.01%of fund net assets
Select Biotechnology Portfolio
FBIOX · Fidelity Select Portfolios
0.12%of fund net assets
Fidelity Growth Company K6 Fund
FGKFX · Fidelity Mt. Vernon Street Trust
0.02%of fund net assets

Fund ownership is a floor, not a census — pensions, insurers and people holding shares directly are not visible here.

Fund ownership counts N-PORT filers only, so it is a floor rather than a census — pensions, insurers and direct holders are not visible here, and the remainder is not “held by individuals”.

Could not be determined for this company: bond issues.

Every fund and institutional holder, quarter by quarter, is on the Ownership tab with a free account.

Connected research

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