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Companies / Health Care / Inspire Medical Systems, Inc.
INSP

Inspire Medical Systems, Inc.

Health CareSurgical & Medical Instruments
Ticker INSPGOLDEN VALLEY, MNFiscal year ends DecemberBook value per share $28.70Diluted shares 28.8M

Inspire Medical Systems, Inc. (NYSE: INSP) is a medical technology company focused on developing and commercializing minimally invasive solutions for patients with obstructive sleep apnea. The company's website is located at InspireSleep.com. From the company’s description.

Fiscal year 2025 · ends 12-31Changes are against fiscal 2024The amber dot is the latest twelve months, to 2026-06-30
Sales & profitability
$911.98M
+13.6% year over year
Last 12 mo $898.74M
5.59%
+1.1 percentage points
Last 12 mo 6.02%
$145.42M
+171.8% year over year
Last 12 mo $135.04M
18.62%
+10.9 percentage points
Last 12 mo 16.36%
Cash & financing
$116.98M
−10.2% year over year
Last 12 mo $157.07M
$78.48M
−13.9% year over year
Last 12 mo $117.09M
—
29.8M
−2.6% year over year
Last 12 mo 28.8M

Margins and return on equity change in ; everything else in percent. Fewer shares and less debt are shown plainly, not as bad news — it depends what you make of buybacks. Dotted labels explain each measure. is shown separately from the annual figures.

What Inspire Medical Systems, Inc. does

In the company’s own words

Inspire Medical Systems, Inc. (NYSE: INSP) is a medical technology company focused on developing and commercializing minimally invasive solutions for patients with obstructive sleep apnea. The company's website is located at InspireSleep.com.

The company's core product is the Inspire system, a proprietary closed-loop neurostimulation technology that represents the first FDA-approved treatment of its kind for moderate to severe obstructive sleep apnea. The Inspire system consists of implantable components including a neurostimulator, stimulation lead, and respiratory sensing capability, along with a patient remote control. The device delivers mild electrical stimulation to the hypoglossal nerve to maintain an open airway during sleep. Physicians have treated more than 125,000 patients with Inspire therapy across the United States, Europe, and Asia.

Inspire operates through a direct sales organization in the U.S. and select European markets, with 295 U.S. sales territories and 21 territories outside the U.S. as of December 31, 2025. The company also sells through distributors in Japan, Singapore, Hong Kong, and Thailand. The company maintains a dedicated market access team focused on reimbursement, prior authorization, coding, and coverage with third-party payors.

The Inspire system received FDA premarket approval in 2014 and has been commercially available in certain European markets since 2011. Japan's Ministry of Health, Labour and Welfare approved the therapy in 2018. In 2024, the company received FDA approval for the Inspire V neurostimulator, which it began marketing in 2025. The company also received expanded FDA indications in 2023 for pediatric patients with Down syndrome and increased the upper AHI limit to 100 events per hour.

Clinical evidence supporting the Inspire system includes the STAR trial published in the New England Journal of Medicine, more than 385 peer-reviewed publications, and the ADHERE global patient registry which achieved its target enrollment of 5,000 patients in 2024. The company maintains a comprehensive intellectual property portfolio with 119 issued U.S. patents and 83 issued foreign patents as of December 31, 2025.

Company details
Sector
Health Care
Industry (SIC)
Surgical & Medical Instruments
Headquarters
GOLDEN VALLEY, MN
Fiscal year end
December
CIK
1609550
SIC
3841

Financial performance, year by year

Fiscal 2018–2025 · USD
$-154.12M$136.63M$427.39M$718.14M$1.01B20182019202020212022202320242025Last 12 moLast 12 monthsLast 12 months

The full income statement, balance sheet and cash flow for each of these years — every figure traceable to its filing — is on the Financials tab with a free account.

Ownership

Who owns Inspire Medical Systems, Inc. — and what changed

Funds as of 2026Q2 · superinvestors as of 2026-06-30

261
funds hold it
0 of 35
superinvestors hold it
$587.95M
held by funds, at market
43.0%
of shares held by funds

Largest fund holders · Inspire Medical Systems, Inc.’s weight in each

VANGUARD HEALTH CARE FUND
VGHCX · VANGUARD SPECIALIZED FUNDS
0.32%of fund net assets
iShares Core S&P Small-Cap ETF
IJR · iShares Trust
0.06%of fund net assets
VANGUARD TOTAL STOCK MARKET INDEX FUND
VTI · VANGUARD INDEX FUNDS
0.00%of fund net assets
iShares Russell 2000 ETF
IWM · iShares Trust
0.04%of fund net assets
VANGUARD SMALL-CAP INDEX FUND
VB · VANGUARD INDEX FUNDS
0.02%of fund net assets

Fund ownership is a floor, not a census — pensions, insurers and people holding shares directly are not visible here.

Fund ownership counts N-PORT filers only, so it is a floor rather than a census — pensions, insurers and direct holders are not visible here, and the remainder is not “held by individuals”.

Every fund and institutional holder, quarter by quarter, is on the Ownership tab with a free account.

Connected research

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