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Companies / Materials / Intellia Therapeutics, Inc.
NTLA

Intellia Therapeutics, Inc.

MaterialsChemicals
Ticker NTLACAMBRIDGE, MAFiscal year ends DecemberBook value per share $5.77Diluted shares 126.1M

Intellia Therapeutics, Inc. (NASDAQ: NTLA) is a leading biopharmaceutical company focused on revolutionizing medicine through CRISPR gene editing and related core technologies. The company's mission centers on transforming the lives of people with severe diseases by developing and commercializing potentially curative… From the company’s description.

Fiscal year 2025 · ends 12-31Changes are against fiscal 2024The amber dot is the latest twelve months, to 2026-06-30
Sales & profitability
$67.67M
+16.9% year over year
Last 12 mo $59.51M
-651.67%
+271.4 percentage points
Last 12 mo -711.66%
$-412.69M
+20.5% year over year
Last 12 mo $-399.97M
-61.47%
−1.9 percentage points
Last 12 mo -54.96%
Cash & financing
$-394.74M
−13.1% year over year
Last 12 mo $-346.64M
$-395.87M
−11.6% year over year
Last 12 mo $-348.69M
—
108.4M
+9.6% year over year
Last 12 mo 126.1M

Margins and return on equity change in ; everything else in percent. Fewer shares and less debt are shown plainly, not as bad news — it depends what you make of buybacks. Dotted labels explain each measure. is shown separately from the annual figures.

What Intellia Therapeutics, Inc. does

In the company’s own words

Intellia Therapeutics, Inc. (NASDAQ: NTLA) is a leading biopharmaceutical company focused on revolutionizing medicine through CRISPR gene editing and related core technologies. The company's mission centers on transforming the lives of people with severe diseases by developing and commercializing potentially curative treatments that address the root causes of disease rather than merely managing symptoms.

The company's lead programs represent the first in vivo genome editing product candidates to advance into Phase 3 clinical development. Lonvoguran ziclumeran, or lonvo-z, is designed to treat hereditary angioedema by inactivating the kallikrein B1 gene in the liver, with the goal of achieving lifelong control of HAE attacks through a single intravenous infusion. Nexiguran ziclumeran, or nex-z, targets transthyretin amyloidosis by inactivating the TTR gene, offering the potential to halt and reverse disease progression in both hereditary and wild-type forms of the condition. Both candidates employ Intellia's proprietary in vivo lipid nanoparticle delivery technology and are administered as one-time outpatient treatments.

Beyond its lead programs, Intellia is expanding its pipeline through independent development and strategic collaborations. The company leverages a decade-plus of research and development experience in multi-modal CRISPR gene editing, oligonucleotide technologies, and lipid nanoparticle delivery systems. Intellia maintains a significant intellectual property portfolio encompassing foundational CRISPR/Cas9 patents and improvements to these systems, with wholly owned and in-licensed patents expected to provide protection through at least 2037.

The company's strategy encompasses advancing clinical development of lead candidates, building fully integrated commercial-stage infrastructure in preparation for potential product launches, expanding its pipeline using proprietary technologies, and collaborating with partners to extend technology reach and maximize return on investment. Intellia has established strategic relationships including a co-development and co-promotion agreement with Regeneron Pharmaceuticals for the ATTR program, as well as collaborations with AvenCell Therapeutics and Kyverna Therapeutics for cell therapy development. The company website is www.intelliatherapeutics.com.

Company details
Sector
Materials
Industry
Chemicals
Headquarters
CAMBRIDGE, MA
Fiscal year end
December
CIK
1652130
SIC
2835

Financial performance, year by year

Fiscal 2016–2025 · USD
$-577.69M$-401.68M$-225.68M$-49.67M$126.34M2016201720182019202020212022202320242025Last 12 moLast 12 monthsLast 12 months

The full income statement, balance sheet and cash flow for each of these years — every figure traceable to its filing — is on the Financials tab with a free account.

Ownership

Who owns Intellia Therapeutics, Inc. — and what changed

Funds as of 2026Q2 · superinvestors as of 2026-06-30

226
funds hold it
0 of 35
superinvestors hold it
$865.60M
held by funds, at market
40.5%
of shares held by funds

Largest fund holders · Intellia Therapeutics, Inc.’s weight in each

ARK Innovation ETF
ARKK · ARK ETF Trust
2.06%of fund net assets
0.91%of fund net assets
VANGUARD TOTAL STOCK MARKET INDEX FUND
VTI · VANGUARD INDEX FUNDS
0.00%of fund net assets
iShares Russell 2000 ETF
IWM · iShares Trust
0.07%of fund net assets
VANGUARD SMALL-CAP INDEX FUND
VB · VANGUARD INDEX FUNDS
0.03%of fund net assets

Fund ownership is a floor, not a census — pensions, insurers and people holding shares directly are not visible here.

Fund ownership counts N-PORT filers only, so it is a floor rather than a census — pensions, insurers and direct holders are not visible here, and the remainder is not “held by individuals”.

Every fund and institutional holder, quarter by quarter, is on the Ownership tab with a free account.

Connected research

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