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Companies / Health Care / Intellia Therapeutics, Inc.
NTLA

Intellia Therapeutics, Inc.

Health CareChemicals
Ticker NTLACAMBRIDGE, MAFiscal year ends DecemberBook value per share $4.69Diluted shares 130.8M

Intellia Therapeutics, Inc. (Nasdaq: NTLA) is a biopharmaceutical company developing therapies using CRISPR gene editing and related technologies, including oligonucleotides and lipid nanoparticles. Its investigational candidates are designed to treat severe diseases by altering their underlying causes. The lead… From the company’s description.

Over the twelve months to Sep 30, 2026, Intellia Therapeutics, Inc. reported revenue of $52.89M, down 8.1% from a year earlier, and a net loss of $426.14M. Its operating margin was −821.2%, and operations used $355.17M in cash. In fiscal 2025, it reported revenue of $67.67M, up 16.9% from fiscal 2024, and a net loss of $412.69M.

Fiscal year 2025 · ends 12-31Changes are against fiscal 2024The amber dot is the latest twelve months, to 2026-09-30
Sales & profitability
$67.67MFY2025
+16.9% year over year
Last 12 mo $52.89M
-651.67%FY2025
+271.4 percentage points
Last 12 mo -821.24%
$-412.69MFY2025
+20.5% year over year
Last 12 mo $-426.14M
-61.47%FY2025
−1.9 percentage points
Last 12 mo -69.51%
Cash & financing
$-394.74MFY2025
−13.1% year over year
Last 12 mo $-355.17M
$-395.87MFY2025
−11.6% year over year
Last 12 mo $-358.08M
—
Last 12 mo 0.12
108.4MFY2025
+9.6% year over year
Last 12 mo 130.8M

Margins and return on equity change in ; everything else in percent. Fewer shares and less debt are shown plainly, not as bad news — it depends what you make of buybacks. Dotted labels explain each measure. is shown separately from the annual figures.

What Intellia Therapeutics, Inc. does

In the company’s own words

Intellia Therapeutics, Inc. (Nasdaq: NTLA) is a biopharmaceutical company developing therapies using CRISPR gene editing and related technologies, including oligonucleotides and lipid nanoparticles. Its investigational candidates are designed to treat severe diseases by altering their underlying causes. The lead programs are lonvoguran ziclumeran for hereditary angioedema and nexiguran ziclumeran for transthyretin amyloidosis; both are in Phase 3 development and are designed as one-time intravenous treatments. The company also advances earlier-stage programs independently and with collaborators, including gene-edited cell therapies. Intellia’s work spans in vivo editing, which modifies genes inside the body, and ex vivo approaches that edit cells for therapeutic use. It collaborates with Regeneron on liver-focused CRISPR programs and co-develops nexiguran ziclumeran with Regeneron, which shares development costs and potential commercial profits. Other collaborations include work on universal CAR-T therapies with AvenCell and Kyverna. Intellia is building commercial capabilities as it prepares for potential product launches. It reported no product sales revenue in the fiscal year ended December 31, 2025. Its website is https://www.intelliatx.com.

Company details
Sector
Health Care
Industry (SIC)
Chemicals
Headquarters
CAMBRIDGE, MA
Fiscal year end
December
CIK
1652130
SIC
2835

Financial performance, year by year

Fiscal 2016–2025 · USD
$-577.69M$-401.68M$-225.68M$-49.67M$126.34M2016201720182019202020212022202320242025Last 12 moLast 12 monthsLast 12 months

The full income statement, balance sheet and cash flow for each of these years — every figure traceable to its filing — is on the Financials tab with a free account.

Ownership

Who owns Intellia Therapeutics, Inc. — and what changed

Funds as of 2026Q2 · superinvestors as of 2026-06-30

226
funds hold it
0 of 35
superinvestors hold it
$865.60M
held by funds, at market
40.4%
of shares held by funds

Largest fund holders · Intellia Therapeutics, Inc.’s weight in each

ARK Innovation ETF
ARKK · ARK ETF Trust
—of fund net assets
0.91%of fund net assets
VANGUARD TOTAL STOCK MARKET INDEX FUND
VTI · VANGUARD INDEX FUNDS
0.00%of fund net assets
iShares Russell 2000 ETF
IWM · iShares Trust
0.07%of fund net assets
VANGUARD SMALL-CAP INDEX FUND
VB · VANGUARD INDEX FUNDS
0.03%of fund net assets

Fund ownership is a floor, not a census — pensions, insurers and people holding shares directly are not visible here.

Fund ownership counts N-PORT filers only, so it is a floor rather than a census — pensions, insurers and direct holders are not visible here, and the remainder is not “held by individuals”.

Every fund and institutional holder, quarter by quarter, is on the Ownership tab with a free account.

Connected research

Put this business in context.

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