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Companies / Health Care / Mirum Pharmaceuticals, Inc.
MIRM

Mirum Pharmaceuticals, Inc.

Health CarePharmaceutical Preparations
Ticker MIRMFOSTER CITY, CAFiscal year ends DecemberBook value per share $-0.87Diluted shares 62.6M

Mirum Pharmaceuticals, Inc. (Nasdaq: MIRM) is a biopharmaceutical company focused on developing and commercializing medicines for rare diseases. Its three approved medicines are LIVMARLI (maralixibat), for cholestatic pruritus associated with Alagille syndrome and progressive familial intrahepatic cholestasis; Ctexli… From the company’s description.

Over the twelve months to Sep 30, 2026, Mirum Pharmaceuticals, Inc. reported revenue of $670.78M, up 42.2% from a year earlier, and a net loss of $903.88M. Its operating margin was −133.6%, and operations used $271.26M in cash. In fiscal 2025, it reported revenue of $521.31M, up 54.7% from fiscal 2024, and a net loss of $23.36M.

Fiscal year 2025 · ends 12-31Changes are against fiscal 2024The amber dot is the latest twelve months, to 2026-09-30
Sales & profitability
$521.31MFY2025
+54.7% year over year
Last 12 mo $670.78M
-4.25%FY2025
+21.8 percentage points
Last 12 mo -133.62%
$-23.36MFY2025
+73.4% year over year
Last 12 mo $-903.88M
-7.42%FY2025
+31.6 percentage points
Last 12 mo 1668.10%
Cash & financing
$55.83MFY2025
+440.7% year over year
Last 12 mo $-271.26M
$54.87MFY2025
+488.0% year over year
Last 12 mo $-273.85M
0.98FY2025
Was 1.37× a year earlier
Last 12 mo -13.50
50.2MFY2025
+5.6% year over year
Last 12 mo 62.6M

Margins and return on equity change in ; everything else in percent. Fewer shares and less debt are shown plainly, not as bad news — it depends what you make of buybacks. Dotted labels explain each measure. is shown separately from the annual figures.

What Mirum Pharmaceuticals, Inc. does

In the company’s own words

Mirum Pharmaceuticals, Inc. (Nasdaq: MIRM) is a biopharmaceutical company focused on developing and commercializing medicines for rare diseases. Its three approved medicines are LIVMARLI (maralixibat), for cholestatic pruritus associated with Alagille syndrome and progressive familial intrahepatic cholestasis; Ctexli (chenodiol), for adults with cerebrotendinous xanthomatosis; and Cholbam (cholic acid), for bile acid synthesis disorders and as adjunctive treatment for peroxisomal disorders, including Zellweger spectrum disorder. Mirum sells these medicines directly in the United States, Canada and certain European countries, and uses licensing and distribution partners in other markets. Its clinical pipeline includes volixibat for primary sclerosing cholangitis and primary biliary cholangitis, brelovitug for chronic hepatitis D infection, and MRM-3379 for fragile X syndrome; it is also studying LIVMARLI in additional rare cholestatic conditions. The company acquired the Cholbam and chenodiol assets in 2023 and acquired Bluejay Therapeutics, including brelovitug, in January 2026.

Company details
Sector
Health Care
Industry (SIC)
Pharmaceutical Preparations
Headquarters
FOSTER CITY, CA
Fiscal year end
December
CIK
1759425
SIC
2834

Financial performance, year by year

Fiscal 2019–2025 · USD
$-1.06B$-588.95M$-116.55M$355.85M$828.24M2019202020212022202320242025Last 12 moLast 12 monthsLast 12 months

The full income statement, balance sheet and cash flow for each of these years — every figure traceable to its filing — is on the Financials tab with a free account.

Ownership

Who owns Mirum Pharmaceuticals, Inc. — and what changed

Funds as of 2026Q2 · superinvestors as of 2026-06-30

365
funds hold it
1 of 35
superinvestors hold it
$2.91B
held by funds, at market
40.0%
of shares held by funds
2
bond issues held by funds

Superinvestors in Mirum Pharmaceuticals, Inc. · what they did last quarter

Polen CapitalINCREASED +1.8%
Polen Capital Management
<0.1%of 13F portfolio

Share of each manager’s reported 13F portfolio. Change is in shares held, since the previous quarter.

Largest fund holders · Mirum Pharmaceuticals, Inc.’s weight in each

VANGUARD TOTAL STOCK MARKET INDEX FUND
VTI · VANGUARD INDEX FUNDS
0.01%of fund net assets
iShares Russell 2000 ETF
IWM · iShares Trust
0.17%of fund net assets
VANGUARD SMALL-CAP INDEX FUND
VB · VANGUARD INDEX FUNDS
0.07%of fund net assets
Strategic Advisers Fidelity U.S. Total Stock Fund
FCTDX · Fidelity Rutland Square Trust II
—of fund net assets
0.14%of fund net assets

Fund ownership is a floor, not a census — pensions, insurers and people holding shares directly are not visible here.

Mirum Pharmaceuticals, Inc.’s bonds, as funds hold them

Funds report holding 2 issues of Mirum Pharmaceuticals, Inc.’s debt, $126.32M at market value — what funds hold, not the company’s total debt. Weighted-average coupon 4.00%, maturing 2029 to 2032.

Fund ownership counts N-PORT filers only, so it is a floor rather than a census — pensions, insurers and direct holders are not visible here, and the remainder is not “held by individuals”.

Fund ownership is a subset of institutional 13F ownership — the two describe overlapping populations and must not be added together.

Every fund and institutional holder, quarter by quarter, is on the Ownership tab with a free account.

Connected research

Put this business in context.

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  • “How do Mirum Pharmaceuticals, Inc. and its peers compare on margins and cash generation over ten years?”
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