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NKTR

NEKTAR THERAPEUTICS

HealthcarePharmaceutical Preparations
Ticker NKTRSAN FRANCISCO, CAFiscal year ends DecemberBook value per share $31.23Diluted shares 28.9M

Nektar Therapeutics (NASDAQ: NKTR) is a clinical-stage, research-based biopharmaceutical company focused on discovering and developing innovative immunomodulatory medicines. The company applies deep understanding of immunology to identify and create drug candidates that selectively induce, amplify, attenuate, or… From the company’s description.

Fiscal year 2025 · ends 12-31Changes are against fiscal 2024The amber dot is the latest twelve months, to 2026-06-30
Sales & profitability
$55.23M
−43.9% year over year
Last 12 mo $54.59M
-253.66%
−146.8 percentage points
Last 12 mo -257.80%
$-164.08M
−37.9% year over year
Last 12 mo $-157.13M
-172.25%
−2.2 percentage points
Last 12 mo -17.40%
Cash & financing
$-208.51M
−18.7% year over year
Last 12 mo $-233.79M
$-208.68M
−17.8% year over year
Last 12 mo $-234.03M
—
16.9M
−91.8% year over year
Last 12 mo 28.9M

Margins and return on equity change in ; everything else in percent. Fewer shares and less debt are shown plainly, not as bad news — it depends what you make of buybacks. Dotted labels explain each measure. is shown separately from the annual figures.

What NEKTAR THERAPEUTICS does

In the company’s own words

Nektar Therapeutics (NASDAQ: NKTR) is a clinical-stage, research-based biopharmaceutical company focused on discovering and developing innovative immunomodulatory medicines. The company applies deep understanding of immunology to identify and create drug candidates that selectively induce, amplify, attenuate, or prevent immune responses to achieve desired therapeutic outcomes across autoimmune diseases and oncology indications.

Nektar's primary pipeline centers on rezpegaldesleukin, a potential first-in-class resolution therapeutic designed to stimulate regulatory T cells by targeting the interleukin-2 receptor complex. The company regained full rights to rezpegaldesleukin in April 2023 following termination of its license agreement with Eli Lilly and Company. The drug candidate is currently in Phase 2b clinical development for atopic dermatitis and alopecia areata, with Fast Track designations granted by the FDA for both indications. The company is also evaluating rezpegaldesleukin in type 1 diabetes through a clinical trial agreement with TrialNet.

In oncology, Nektar develops NKTR-255, an investigational biologic targeting the interleukin-15 pathway to activate innate and adaptive immunity for cancer treatment. The company is conducting select developmental studies in combination with cell therapies and checkpoint inhibitors while exploring strategic partnership opportunities. Additional pipeline programs include NKTR-0165 and NKTR-0166, preclinical TNF receptor type II agonist assets being developed for autoimmune diseases, and NKTR-422, a PEG-modified colony stimulating factor program targeting inflammation and fibrosis.

Nektar's technology platform centers on advanced polymer conjugate technology involving polyethylene glycol conjugation, commonly known as PEGylation. This proven technology has supported the development of multiple approved products including Neulasta, CIMZIA, and MIRCERA. In December 2024, Nektar sold its manufacturing facility in Huntsville, Alabama to Gannet BioChem and retained an approximate twenty percent equity investment, while maintaining supply agreements for polyethylene glycol reagents essential to its drug development programs.

The company operates as a smaller reporting company and is not a well-known seasoned issuer. Nektar maintains collaboration partnerships with various biotechnology and pharmaceutical companies and continues investing substantially in research and development to advance its pipeline of immunomodulatory drug candidates.

Company details
Sector
Healthcare
Industry
Pharmaceutical Preparations
Headquarters
SAN FRANCISCO, CA
Fiscal year end
December
CIK
906709
SIC
2834

Financial performance, year by year

Fiscal 2013–2025 · USD
$-695.55M$-180.40M$334.74M$849.89M$1.37B2013201420152016201720182019202020212022202320242025Last 12 moLast 12 monthsLast 12 months

The full income statement, balance sheet and cash flow for each of these years — every figure traceable to its filing — is on the Financials tab with a free account.

Ownership

Who owns NEKTAR THERAPEUTICS — and what changed

Funds as of 2026Q2 · superinvestors as of 2026-06-30

132
funds hold it
0 of 35
superinvestors hold it
$557.34M
held by funds, at market
23.4%
of shares held by funds

Largest fund holders · NEKTAR THERAPEUTICS’s weight in each

Fidelity Growth Company Fund
FDGRX · Fidelity Mt. Vernon Street Trust
0.12%of fund net assets
VANGUARD TOTAL STOCK MARKET INDEX FUND
VTI · VANGUARD INDEX FUNDS
0.00%of fund net assets
iShares Russell 2000 ETF
IWM · iShares Trust
0.08%of fund net assets
Fidelity Growth Company K6 Fund
FGKFX · Fidelity Mt. Vernon Street Trust
0.12%of fund net assets
Fidelity Series Growth Company Fund
FCGSX · Fidelity Mt. Vernon Street Trust
0.11%of fund net assets

Fund ownership is a floor, not a census — pensions, insurers and people holding shares directly are not visible here.

Fund ownership counts N-PORT filers only, so it is a floor rather than a census — pensions, insurers and direct holders are not visible here, and the remainder is not “held by individuals”.

Every fund and institutional holder, quarter by quarter, is on the Ownership tab with a free account.

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