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Companies / Health Care / Nurix Therapeutics, Inc.
NRIX

Nurix Therapeutics, Inc.

Health CarePharmaceutical Preparations
Ticker NRIXBRISBANE, CAFiscal year ends NovemberBook value per share $8.47Diluted shares 114.4M

Nurix Therapeutics (Nasdaq: NRIX) is a clinical-stage biopharmaceutical company that discovers and develops targeted protein degradation medicines for cancer and inflammatory diseases. Its wholly owned clinical pipeline includes bexobrutideg, a BTK degrader, and zelebrudomide, which degrades BTK and the transcription… From the company’s description.

Over the twelve months to Aug 31, 2026, Nurix Therapeutics, Inc. reported revenue of $701.94M, up 738.8% from a year earlier, and net income of $294.88M. Its operating margin was 41.3%, and operations generated $379.31M in cash. In fiscal 2025, it reported revenue of $83.98M, up 54.0% from fiscal 2024, and a net loss of $264.46M.

Fiscal year 2025 · ends 11-30Changes are against fiscal 2024The amber dot is the latest twelve months, to 2026-08-31
Sales & profitability
$83.98MFY2025
+54.0% year over year
Last 12 mo $701.94M
-340.16%FY2025
+50.4 percentage points
Last 12 mo 41.27%
$-264.46MFY2025
−36.6% year over year
Last 12 mo $294.88M
-49.09%FY2025
−12.4 percentage points
Last 12 mo 30.45%
Cash & financing
$-249.47MFY2025
−44.5% year over year
Last 12 mo $379.31M
$-263.47MFY2025
−44.9% year over year
Last 12 mo $369.81M
—
86.7MFY2025
+29.1% year over year
Last 12 mo 114.4M

Margins and return on equity change in ; everything else in percent. Fewer shares and less debt are shown plainly, not as bad news — it depends what you make of buybacks. Dotted labels explain each measure. is shown separately from the annual figures.

What Nurix Therapeutics, Inc. does

In the company’s own words

Nurix Therapeutics (Nasdaq: NRIX) is a clinical-stage biopharmaceutical company that discovers and develops targeted protein degradation medicines for cancer and inflammatory diseases. Its wholly owned clinical pipeline includes bexobrutideg, a BTK degrader, and zelebrudomide, which degrades BTK and the transcription factors Ikaros and Aiolos, both being studied for B-cell malignancies, as well as NX-1607, a CBL-B inhibitor being studied in solid tumors. Nurix also advances preclinical protein degraders and degrader antibody conjugates, and uses its DEL-AI discovery platform in partnered programs with Gilead, Sanofi and Pfizer, including drug candidates for inflammatory conditions and Type 2 inflammation. The company retains certain U.S. co-development, co-commercialization and profit-sharing options under these collaborations. Its wholly owned and partnered research programs address oncology, inflammation and immunology, with discovery work supported by machine-learning tools and DNA-encoded library screening. As of November 30, 2025, Nurix had received $482 million in non-dilutive collaborator funding and was eligible for potential future fees and milestone payments.

Company details
Sector
Health Care
Industry (SIC)
Pharmaceutical Preparations
Headquarters
BRISBANE, CA
Fiscal year end
November
CIK
1549595
SIC
2834

Financial performance, year by year

Fiscal 2020–2025 · USD
$-361.10M$-71.18M$218.74M$508.66M$798.58M202020212022202320242025Last 12 moLast 12 monthsLast 12 months

The full income statement, balance sheet and cash flow for each of these years — every figure traceable to its filing — is on the Financials tab with a free account.

Ownership

Who owns Nurix Therapeutics, Inc. — and what changed

Funds as of 2026Q2 · superinvestors as of 2026-06-30

198
funds hold it
0 of 35
superinvestors hold it
$700.22M
held by funds, at market
29.6%
of shares held by funds

Largest fund holders · Nurix Therapeutics, Inc.’s weight in each

VANGUARD TOTAL STOCK MARKET INDEX FUND
VTI · VANGUARD INDEX FUNDS
0.00%of fund net assets
iShares Russell 2000 ETF
IWM · iShares Trust
0.07%of fund net assets
0.56%of fund net assets
0.04%of fund net assets
Eventide Healthcare & Life Sciences Fund
ETAHX · MUTUAL FUND SERIES TRUST
1.76%of fund net assets

Fund ownership is a floor, not a census — pensions, insurers and people holding shares directly are not visible here.

Fund ownership counts N-PORT filers only, so it is a floor rather than a census — pensions, insurers and direct holders are not visible here, and the remainder is not “held by individuals”.

Could not be determined for this company: bond issues.

Every fund and institutional holder, quarter by quarter, is on the Ownership tab with a free account.

Connected research

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