10x Insights
Loading account…
Companies / Healthcare / Oric Pharmaceuticals, Inc.
ORIC

Oric Pharmaceuticals, Inc.

HealthcarePharmaceutical Preparations
Ticker ORICSOUTH SAN FRANCISCO, CAFiscal year ends DecemberBook value per share $3.57Diluted shares 106.7M

ORIC Pharmaceuticals is a clinical-stage biopharmaceutical company dedicated to developing innovative cancer therapeutics designed to overcome resistance mechanisms that limit the efficacy of existing treatments. The company operates under the ticker symbol ORIC on the Nasdaq Global Select Market and maintains its… From the company’s description.

Fiscal year 2025 · ends 12-31Changes are against fiscal 2024The amber dot is the latest twelve months, to 2026-06-30
Sales & profitability
—
0.00%
$-129.47M
−1.3% year over year
Last 12 mo $-140.35M
-33.68%
+18.9 percentage points
Last 12 mo -36.81%
Cash & financing
$-110.97M
+1.5% year over year
Last 12 mo $-111.64M
$-111.68M
+1.9% year over year
Last 12 mo $-112.26M
—
87.8M
+25.9% year over year
Last 12 mo 106.7M

Margins and return on equity change in ; everything else in percent. Fewer shares and less debt are shown plainly, not as bad news — it depends what you make of buybacks. Dotted labels explain each measure. is shown separately from the annual figures.

What Oric Pharmaceuticals, Inc. does

In the company’s own words

ORIC Pharmaceuticals is a clinical-stage biopharmaceutical company dedicated to developing innovative cancer therapeutics designed to overcome resistance mechanisms that limit the efficacy of existing treatments. The company operates under the ticker symbol ORIC on the Nasdaq Global Select Market and maintains its corporate presence at oricpharma.com.

The company's pipeline centers on two lead clinical-stage product candidates. Rinzimetostat is an allosteric inhibitor of polycomb repressive complex 2 targeting the EED subunit, licensed from Mirati Therapeutics and currently in Phase 1b development for metastatic castration-resistant prostate cancer in combination with approved androgen receptor inhibitors. Enozertinib is a brain-penetrant, orally bioavailable irreversible inhibitor targeting EGFR exon 20 and EGFR atypical mutations, licensed from Voronoi Inc. and being evaluated in Phase 1b trials for non-small cell lung cancer with CNS metastases. The company has established clinical collaboration and supply agreements with Johnson & Johnson and Bayer to advance these programs.

ORIC's business model leverages the extensive oncology expertise of its founders and management team, who collectively have decades of experience identifying and developing cancer therapeutics including approved drugs such as Rozlytrek, Erleada, Gleevec, and Sprycel. The company applies a precision medicine approach utilizing biomarkers for target engagement demonstration and patient selection across its development programs.

The company's competitive advantages derive from its specialized expertise in three areas: hormone-dependent cancers, precision oncology, and key tumor dependencies. ORIC maintains an integrated research and development infrastructure with in-house capabilities spanning biology, translational medicine, pharmacology, computational biology, biomarker development, clinical development, regulatory affairs, and commercial functions. As of December 31, 2025, the company employed 104 full-time employees.

In August 2025, ORIC announced a strategic pipeline prioritization to focus resources on advancing its two lead clinical programs, resulting in elimination of its discovery research group and substantial reduction in preclinical research activities. The company owns or licenses full worldwide development and commercialization rights to its programs, with the exception of enozertinib rights outside the ORIC Territory comprising mainland China, Hong Kong, Macau, and Taiwan.

Company details
Sector
Healthcare
Industry
Pharmaceutical Preparations
Headquarters
SOUTH SAN FRANCISCO, CA
Fiscal year end
December
CIK
1796280
SIC
2834

Financial performance, year by year

Fiscal 2020–2025 · USD
$-147.02M$-127.02M$-107.03M$-87.03M$-67.04M202020212022202320242025Last 12 moLast 12 months

The full income statement, balance sheet and cash flow for each of these years — every figure traceable to its filing — is on the Financials tab with a free account.

Ownership

Who owns Oric Pharmaceuticals, Inc. — and what changed

Funds as of 2026Q2 · superinvestors as of 2026-06-30

197
funds hold it
0 of 35
superinvestors hold it
$307.62M
held by funds, at market
28.4%
of shares held by funds

Largest fund holders · Oric Pharmaceuticals, Inc.’s weight in each

0.33%of fund net assets
VANGUARD TOTAL STOCK MARKET INDEX FUND
VTI · VANGUARD INDEX FUNDS
0.00%of fund net assets
iShares Russell 2000 ETF
IWM · iShares Trust
0.03%of fund net assets
0.17%of fund net assets
T. Rowe Price Health Sciences Fund, Inc.
PRHSX · T. ROWE PRICE HEALTH SCIENCES FUND, INC.
0.14%of fund net assets

Fund ownership is a floor, not a census — pensions, insurers and people holding shares directly are not visible here.

Fund ownership counts N-PORT filers only, so it is a floor rather than a census — pensions, insurers and direct holders are not visible here, and the remainder is not “held by individuals”.

Every fund and institutional holder, quarter by quarter, is on the Ownership tab with a free account.

Connected research

Put this business in context.

Compare this company with peers, find it in your funds and follow its financial history with your connected AI:

  • “How do Oric Pharmaceuticals, Inc. and its peers compare on margins and cash generation over ten years?”
  • “Where did five years of Oric Pharmaceuticals, Inc.'s earnings go — cash, debt, buybacks, reinvestment?”
  • “What changed in Oric Pharmaceuticals, Inc.'s last four quarterly filings that the numbers alone won't show?”
See how it works →All research tools with a subscription. Use your own AI account.