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PFE

Pfizer

Health CarePharmaceutical PreparationsS&P 500
Ticker PFENEW YORK, NYFiscal year ends DecemberBook value per share $14.86Diluted shares 5.7B

Pfizer Inc. (NYSE: PFE) is a research-based global biopharmaceutical company headquartered in New York and operates through its website at www.pfizer.com. The company applies science and global resources to discover, develop, manufacture, market, sell and distribute biopharmaceutical products worldwide, focusing on… From the company’s description.

Fiscal year 2025 · ends 12-31Changes are against fiscal 2024The amber dot is the latest twelve months, to 2026-06-28
Sales & profitability
$62.58BFY2025
−1.6% year over year
Last 12 mo $63.70B
13.49%FY2025
No change, year over year
Last 12 mo 4.69%
$7.79BFY2025
−3.3% year over year
Last 12 mo $4.37B
10.84%FY2025
−1 percentage points
Last 12 mo 5.09%
Cash & financing
$11.70BFY2025
−8.2% year over year
Last 12 mo $13.40B
$9.07BFY2025
−7.7% year over year
Last 12 mo $10.98B
0.75FY2025
Was 0.73× a year earlier
Last 12 mo 0.74
5.7BFY2025
+0.2% year over year
Last 12 mo 5.7B

Margins and return on equity change in ; everything else in percent. Fewer shares and less debt are shown plainly, not as bad news — it depends what you make of buybacks. Dotted labels explain each measure. is shown separately from the annual figures.

What Pfizer does

In the company’s own words

Pfizer Inc. (NYSE: PFE) is a research-based global biopharmaceutical company headquartered in New York and operates through its website at www.pfizer.com. The company applies science and global resources to discover, develop, manufacture, market, sell and distribute biopharmaceutical products worldwide, focusing on extending and significantly improving patients' lives through medicines and vaccines that address major diseases.

The company operates through three primary divisions within its Biopharma reportable segment, which represents the only reportable segment. The Pfizer U.S. Commercial Division commercializes the entire product portfolio in the United States. The Pfizer International Commercial Division handles commercialization across all international markets. The Global Hospital and Biosimilars organization manages off-patent branded and generic sterile injectables and biosimilars. Additionally, Pfizer operates PC1, a contract development and manufacturing organization supplying specialty active pharmaceutical ingredients, and Pfizer Ignite, which provides R&D services to biotech companies, though the company decided to discontinue Ignite in 2025.

Pfizer's product portfolio spans four primary therapeutic areas: oncology, internal medicine including cardiometabolic and weight management treatments, vaccines for infectious diseases, and inflammation and immunology. Major brands include Comirnaty (COVID-19 vaccine developed with BioNTech), Paxlovid (COVID-19 treatment), Eliquis (anticoagulant), Prevnar family (pneumococcal vaccines), Xtandi (prostate cancer treatment), Ibrance (breast cancer treatment), and the Vyndaqel family (amyloidosis treatment). The company also maintains collaboration and co-promotion agreements with partners including BioNTech, Bristol-Myers Squibb, and Astellas for various products.

The company's R&D operations are managed through a single global organization focused on discovering and developing highly differentiated medicines and vaccines. As of early 2026, Pfizer maintained numerous projects in various development stages across its therapeutic focus areas. The company pursues business development through acquisitions, in-licensing agreements, and strategic partnerships to enhance its pipeline and capabilities. Recent significant transactions include the November 2025 acquisition of Metsera and the December 2023 acquisition of Seagen, along with in-licensing agreements with YaoPharma and 3SBio in obesity, cardiometabolic diseases, and oncology.

Company details
Sector
Health Care
Industry (SIC)
Pharmaceutical Preparations
Headquarters
NEW YORK, NY
Fiscal year end
December
CIK
78003
SIC
2834

Financial performance, year by year

Fiscal 2013–2025 · USD
$-10.03B$20.07B$50.16B$80.26B$110.36B2013201420152016201720182019202020212022202320242025Last 12 moLast 12 monthsLast 12 months

The full income statement, balance sheet and cash flow for each of these years — every figure traceable to its filing — is on the Financials tab with a free account.

Ownership

Who owns Pfizer — and what changed

Funds as of 2026Q2 · superinvestors as of 2026-06-30

977
funds hold it
3 of 35
superinvestors hold it
$33.60B
held by funds, at market
23.7%
of shares held by funds
38
bond issues held by funds

Superinvestors in Pfizer · what they did last quarter

Prem WatsaINCREASED +5.3%
Fairfax Financial Holdings
1.0%of 13F portfolio
Bruce BerkowitzNEW
Fairholme Capital Management
0.4%of 13F portfolio
Mark HillmanDECREASED -7.1%
Hillman Capital Management
3.0%of 13F portfolio

Share of each manager’s reported 13F portfolio. Change is in shares held, since the previous quarter.

Largest fund holders · Pfizer’s weight in each

VANGUARD TOTAL STOCK MARKET INDEX FUND
VTI · VANGUARD INDEX FUNDS
0.19%of fund net assets
VANGUARD 500 INDEX FUND
VOO · VANGUARD INDEX FUNDS
0.21%of fund net assets
Fidelity 500 Index Fund
FXAIX · Fidelity Concord Street Trust
0.23%of fund net assets
iShares Core S&P 500 ETF
IVV · iShares Trust
0.21%of fund net assets

Fund ownership is a floor, not a census — pensions, insurers and people holding shares directly are not visible here.

Pfizer’s bonds, as funds hold them

Funds report holding 38 issues of Pfizer’s debt, $6.49B at market value — what funds hold, not the company’s total debt. Weighted-average coupon 4.47%, maturing 2026 to 2065.

Fund ownership counts N-PORT filers only, so it is a floor rather than a census — pensions, insurers and direct holders are not visible here, and the remainder is not “held by individuals”.

Fund ownership is a subset of institutional 13F ownership — the two describe overlapping populations and must not be added together.

Every fund and institutional holder, quarter by quarter, is on the Ownership tab with a free account.

Connected research

Put this business in context.

Compare this company with peers, find it in your funds and follow its financial history with your connected AI:

  • “How do Pfizer and its peers compare on margins and cash generation over ten years?”
  • “Where did five years of Pfizer's earnings go — cash, debt, buybacks, reinvestment?”
  • “What changed in Pfizer's last four quarterly filings that the numbers alone won't show?”
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