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Companies / Health Care / Rapport Therapeutics, Inc.
RAPP

Rapport Therapeutics, Inc.

Health CarePharmaceutical Preparations
Ticker RAPPBOSTON, MAFiscal year ends DecemberBook value per share $8.24Diluted shares 47.5M

Rapport Therapeutics (Nasdaq: RAPP) is a clinical-stage biotechnology company developing small-molecule medicines for neurological and psychiatric disorders. Its RAP technology platform uses knowledge of receptor-associated proteins to identify drug targets and develop medicines designed to act on specific receptor… From the company’s description.

In fiscal 2025, Rapport Therapeutics, Inc. reported a net loss of $111.48M. Operations used $87.47M in cash.

Fiscal year 2025 · ends 12-31Changes are against fiscal 2024The amber dot is the latest twelve months, to 2026-09-30
Sales & profitability
—
0.00%FY2025
$-111.48MFY2025
−42.4% year over year
Last 12 mo $-150.47M
-23.00%FY2025
+2.6 percentage points
Last 12 mo -38.46%
Cash & financing
$-87.47MFY2025
−34.9% year over year
Last 12 mo $-120.85M
$-88.09MFY2025
−31.0% year over year
Last 12 mo $-121.18M
—
38.9MFY2025
+87.7% year over year
Last 12 mo 47.5M

Margins and return on equity change in ; everything else in percent. Fewer shares and less debt are shown plainly, not as bad news — it depends what you make of buybacks. Dotted labels explain each measure. is shown separately from the annual figures.

What Rapport Therapeutics, Inc. does

In the company’s own words

Rapport Therapeutics (Nasdaq: RAPP) is a clinical-stage biotechnology company developing small-molecule medicines for neurological and psychiatric disorders. Its RAP technology platform uses knowledge of receptor-associated proteins to identify drug targets and develop medicines designed to act on specific receptor variants or brain regions. The lead candidate, RAP-219, is an AMPA receptor modulator targeting TARPγ8, and is being developed for focal onset seizures, primary generalized tonic-clonic seizures and bipolar mania. Other programs include RAP-641, an α6β4 nicotinic acetylcholine receptor agonist in development for chronic pain and migraine, and discovery-stage α9α10 receptor modulators for hearing and vestibular disorders. Rapport operates as a single drug-discovery and development business, with programs spanning clinical development and earlier-stage research. Founded in 2022 with support from Third Rock Ventures and Johnson & Johnson Innovation-JJDC, the company licensed certain TARPγ8 and nicotinic acetylcholine receptor assets from Janssen Pharmaceutical in 2022. Its website is https://rapporttherapeutics.com/.

Company details
Sector
Health Care
Industry (SIC)
Pharmaceutical Preparations
Headquarters
BOSTON, MA
Fiscal year end
December
CIK
2012593
SIC
2834

Financial performance, year by year

Fiscal 2024–2025 · USD
$-157.69M$-136.04M$-114.39M$-92.74M$-71.09M20242025Last 12 moLast 12 months

The full income statement, balance sheet and cash flow for each of these years — every figure traceable to its filing — is on the Financials tab with a free account.

Ownership

Who owns Rapport Therapeutics, Inc. — and what changed

Funds as of 2026Q2 · superinvestors as of 2026-06-30

173
funds hold it
0 of 35
superinvestors hold it
$570.92M
held by funds, at market
23.9%
of shares held by funds

Largest fund holders · Rapport Therapeutics, Inc.’s weight in each

0.15%of fund net assets
Fidelity Growth Company Fund
FDGRX · Fidelity Mt. Vernon Street Trust
—of fund net assets
VANGUARD TOTAL STOCK MARKET INDEX FUND
VTI · VANGUARD INDEX FUNDS
0.00%of fund net assets
iShares Russell 2000 ETF
IWM · iShares Trust
0.04%of fund net assets
Fidelity Growth Company K6 Fund
FGKFX · Fidelity Mt. Vernon Street Trust
—of fund net assets

Fund ownership is a floor, not a census — pensions, insurers and people holding shares directly are not visible here.

Fund ownership counts N-PORT filers only, so it is a floor rather than a census — pensions, insurers and direct holders are not visible here, and the remainder is not “held by individuals”.

Could not be determined for this company: bond issues.

Every fund and institutional holder, quarter by quarter, is on the Ownership tab with a free account.

Connected research

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