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Companies / Health Care / Schrodinger, Inc.
SDGR

Schrodinger, Inc.

Health CarePharmaceutical Preparations
Ticker SDGRNEW YORK, NYFiscal year ends DecemberBook value per share $4.05Diluted shares 74.5M

Schrödinger (Nasdaq: SDGR) develops computational software and uses its platform to discover molecules for drug development and materials applications. Its software combines physics-based methods and machine learning to support molecule discovery, design, and optimization, and is licensed to biopharmaceutical and… From the company’s description.

Over the twelve months to Sep 30, 2026, Schrodinger, Inc. reported revenue of $269.20M, up 4.8% from a year earlier, and a net loss of $59.25M. Its operating margin was −49.6%, and operations used $112.58M in cash. In fiscal 2025, it reported revenue of $255.87M, up 23.3% from fiscal 2024, and a net loss of $103.27M.

Fiscal year 2025 · ends 12-31Changes are against fiscal 2024The amber dot is the latest twelve months, to 2026-09-30
Sales & profitability
$255.87MFY2025
+23.3% year over year
Last 12 mo $269.20M
-65.23%FY2025
+35.6 percentage points
Last 12 mo -49.64%
$-103.27MFY2025
+44.8% year over year
Last 12 mo $-59.25M
-28.37%FY2025
+16 percentage points
Last 12 mo -19.63%
Cash & financing
$13.90MFY2025
+108.8% year over year
Last 12 mo $-112.58M
$12.46MFY2025
+107.6% year over year
Last 12 mo $-116.77M
—
73.4MFY2025
+1.1% year over year
Last 12 mo 74.5M

Margins and return on equity change in ; everything else in percent. Fewer shares and less debt are shown plainly, not as bad news — it depends what you make of buybacks. Dotted labels explain each measure. is shown separately from the annual figures.

What Schrodinger, Inc. does

In the company’s own words

Schrödinger (Nasdaq: SDGR) develops computational software and uses its platform to discover molecules for drug development and materials applications. Its software combines physics-based methods and machine learning to support molecule discovery, design, and optimization, and is licensed to biopharmaceutical and industrial companies, academic institutions, and government laboratories. Products include Glide, FEP+, LiveDesign, and Maestro; materials science applications include electronics, aerospace, semiconductors, energy, and chemicals. The company also applies its platform in collaborative drug discovery programs and proprietary programs, with collaborators pursuing research across therapeutic areas and Schrödinger advancing selected candidates through preclinical and clinical development. Its two business areas are software and drug discovery: 2025 software revenue was $199.5 million and drug discovery revenue was $56.4 million, out of $255.9 million in total revenue. As of December 31, 2025, it had 20 active collaborative drug discovery programs. Founded in 1990, Schrödinger began developing its proprietary drug pipeline in 2018. Its website is https://www.schrodinger.com/.

Company details
Sector
Health Care
Industry (SIC)
Pharmaceutical Preparations
Headquarters
NEW YORK, NY
Fiscal year end
December
CIK
1490978
SIC
2834

Financial performance, year by year

Fiscal 2020–2025 · USD
$-232.76M$-95.86M$41.04M$177.94M$314.83M202020212022202320242025Last 12 moLast 12 monthsLast 12 months

The full income statement, balance sheet and cash flow for each of these years — every figure traceable to its filing — is on the Financials tab with a free account.

Ownership

Who owns Schrodinger, Inc. — and what changed

Funds as of 2026Q2 · superinvestors as of 2026-06-30

188
funds hold it
0 of 35
superinvestors hold it
$340.58M
held by funds, at market

Largest fund holders · Schrodinger, Inc.’s weight in each

iShares Core S&P Small-Cap ETF
IJR · iShares Trust
0.05%of fund net assets
VANGUARD TOTAL STOCK MARKET INDEX FUND
VTI · VANGUARD INDEX FUNDS
0.00%of fund net assets
ARK Genomic Revolution ETF
ARKG · ARK ETF Trust
—of fund net assets
iShares Russell 2000 ETF
IWM · iShares Trust
0.03%of fund net assets
VANGUARD SMALL-CAP INDEX FUND
VB · VANGUARD INDEX FUNDS
0.01%of fund net assets

Fund ownership is a floor, not a census — pensions, insurers and people holding shares directly are not visible here.

Every fund and institutional holder, quarter by quarter, is on the Ownership tab with a free account.

Connected research

Put this business in context.

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