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Companies / Health Care / Tectonic Therapeutic, Inc.
TECX

Tectonic Therapeutic, Inc.

Health CareBiological Products
Ticker TECXWATERTOWN, MAFiscal year ends DecemberBook value per share $11.98Diluted shares 19.1M

Tectonic Therapeutic, Inc. (Nasdaq: TECX) is a clinical-stage biotechnology company discovering and developing therapeutic proteins and antibodies that modulate G-protein-coupled receptors (GPCRs). Its proprietary GEODe platform is designed to support biologic drug discovery against GPCR targets. The company’s lead… From the company’s description.

In fiscal 2025, Tectonic Therapeutic, Inc. reported a net loss of $74.15M. Operations used $60.08M in cash.

Fiscal year 2025 · ends 12-31Changes are against fiscal 2024The amber dot is the latest twelve months, to 2026-09-30
Sales & profitability
—
0.00%FY2025
$-74.15MFY2025
−27.9% year over year
Last 12 mo $-88.10M
-29.50%FY2025
+11.7 percentage points
Last 12 mo -38.42%
Cash & financing
$-60.08MFY2025
−1.7% year over year
Last 12 mo $-69.23M
$-60.29MFY2025
−1.8% year over year
Last 12 mo $-69.33M
0.00FY2025
Was 0.01× a year earlier
Last 12 mo 0.00
18.3MFY2025
+115.8% year over year
Last 12 mo 19.1M

Margins and return on equity change in ; everything else in percent. Fewer shares and less debt are shown plainly, not as bad news — it depends what you make of buybacks. Dotted labels explain each measure. is shown separately from the annual figures.

What Tectonic Therapeutic, Inc. does

In the company’s own words

Tectonic Therapeutic, Inc. (Nasdaq: TECX) is a clinical-stage biotechnology company discovering and developing therapeutic proteins and antibodies that modulate G-protein-coupled receptors (GPCRs). Its proprietary GEODe platform is designed to support biologic drug discovery against GPCR targets. The company’s lead candidate, TX45, is an Fc-relaxin fusion molecule that activates the RXFP1 receptor and is being studied for pulmonary hypertension associated with heart failure with preserved ejection fraction and interstitial lung disease. TX2100, an antibody antagonist of the APJ receptor, is in early clinical development for hereditary hemorrhagic telangiectasia, a genetic bleeding disorder. A third program is developing a GPCR-modulating bispecific candidate for fibrotic diseases. Tectonic has no reportable business segments described; its activities center on research and development, and it has not established commercial or distribution capabilities. It relies on third-party manufacturers for clinical and potential future commercial production. The company’s programs are in clinical or discovery-stage development, with no marketed products described.

Company details
Sector
Health Care
Industry (SIC)
Biological Products
Headquarters
WATERTOWN, MA
Fiscal year end
December
CIK
1681087
SIC
2836

Financial performance, year by year

Fiscal 2018–2025 · USD
$-132.90M$-93.34M$-53.78M$-14.22M$25.34M20182019202020212022202320242025Last 12 moLast 12 months

The full income statement, balance sheet and cash flow for each of these years — every figure traceable to its filing — is on the Financials tab with a free account.

Ownership

Who owns Tectonic Therapeutic, Inc. — and what changed

Funds as of 2026Q2 · superinvestors as of 2026-06-30

124
funds hold it
0 of 35
superinvestors hold it
$148.22M
held by funds, at market
22.8%
of shares held by funds

Largest fund holders · Tectonic Therapeutic, Inc.’s weight in each

1.95%of fund net assets
Fidelity Growth Company Fund
FDGRX · Fidelity Mt. Vernon Street Trust
—of fund net assets
1.85%of fund net assets
Select Biotechnology Portfolio
FBIOX · Fidelity Select Portfolios
—of fund net assets
VANGUARD TOTAL STOCK MARKET INDEX FUND
VTI · VANGUARD INDEX FUNDS
0.00%of fund net assets

Fund ownership is a floor, not a census — pensions, insurers and people holding shares directly are not visible here.

Fund ownership counts N-PORT filers only, so it is a floor rather than a census — pensions, insurers and direct holders are not visible here, and the remainder is not “held by individuals”.

Could not be determined for this company: bond issues.

Every fund and institutional holder, quarter by quarter, is on the Ownership tab with a free account.

Connected research

Put this business in context.

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