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Companies / Healthcare / TG THERAPEUTICS, INC.
TGTX

TG THERAPEUTICS, INC.

HealthcarePharmaceutical Preparations
Ticker TGTXNEW YORK, NYFiscal year ends DecemberBook value per share $3.81Diluted shares 158.7M

TG Therapeutics, Inc. (NASDAQ: TGTX) is a fully integrated, commercial-stage biotechnology company focused on the acquisition, development, and commercialization of novel treatments for B-cell mediated diseases. The company maintains its corporate website at www.tgtherapeutics.com. From the company’s description.

Fiscal year 2025 · ends 12-31Changes are against fiscal 2024The amber dot is the latest twelve months, to 2026-06-30
Sales & profitability
$616.29M
+87.3% year over year
Last 12 mo $799.54M
20.01%
+7.3 percentage points
Last 12 mo 17.05%
$447.18M
+1812.4% year over year
Last 12 mo $441.49M
69.01%
+58.5 percentage points
Last 12 mo 73.08%
Cash & financing
$-24.77M
+38.9% year over year
Last 12 mo $17.88M
$-24.99M
+38.4% year over year
Last 12 mo $17.39M
0.38
Was 1.10× a year earlier
Last 12 mo 1.23
161.4M
+0.7% year over year
Last 12 mo 158.7M

Margins and return on equity change in ; everything else in percent. Fewer shares and less debt are shown plainly, not as bad news — it depends what you make of buybacks. Dotted labels explain each measure. is shown separately from the annual figures.

What TG THERAPEUTICS, INC. does

In the company’s own words

TG Therapeutics, Inc. (NASDAQ: TGTX) is a fully integrated, commercial-stage biotechnology company focused on the acquisition, development, and commercialization of novel treatments for B-cell mediated diseases. The company maintains its corporate website at www.tgtherapeutics.com.

The company's flagship product is BRIUMVI (ublituximab-xiiy), an anti-CD20 monoclonal antibody approved by the FDA in December 2022 for treating adult patients with relapsing forms of multiple sclerosis, including clinically isolated syndrome, relapsing-remitting disease, and active secondary progressive disease. BRIUMVI can be administered via one-hour intravenous infusion every 24 weeks following an initial dosing schedule. The company commercially launched BRIUMVI in the United States in January 2023 and has expanded its availability internationally through a commercialization partnership with Neuraxpharm, a European specialty pharmaceutical company focused on central nervous system disorders. BRIUMVI became available in the European market in February 2024 and is now commercially available in several countries outside the United States.

Beyond its approved product, TG Therapeutics maintains an active pipeline addressing B-cell mediated diseases. The company is evaluating subcutaneous formulations of ublituximab through Phase 3 clinical trials, with enrollment exceeding 75 percent as of February 2026. Additionally, the company is developing simplified dosing schedules for intravenous BRIUMVI and exploring azer-cel, an allogeneic CD19-directed CAR T cell therapy, for progressive forms of multiple sclerosis through Phase 1 trials initiated in August 2025.

The company's business model centers on identifying validated targets in B-cell mediated diseases and acquiring best-in-class compounds with complementary mechanisms. TG Therapeutics licenses its products through strategic partnerships, including exclusive worldwide development and commercial rights for ublituximab from LFB Biotechnologies and GTC Biotherapeutics. The company maintains a patient-focused culture while building its commercial infrastructure to support BRIUMVI's market penetration and pipeline advancement. TG Therapeutics operates as an accelerated filer with the SEC and maintains a well-known seasoned issuer status.

Company details
Sector
Healthcare
Industry
Pharmaceutical Preparations
Headquarters
NEW YORK, NY
Fiscal year end
December
CIK
1001316
SIC
2834

Financial performance, year by year

Fiscal 2013–2025 · USD
$-462.86M$-118.57M$225.72M$570.01M$914.30M2013201420152016201720182019202020212022202320242025Last 12 moLast 12 monthsLast 12 months

The full income statement, balance sheet and cash flow for each of these years — every figure traceable to its filing — is on the Financials tab with a free account.

Ownership

Who owns TG THERAPEUTICS, INC. — and what changed

Funds as of 2026Q2 · superinvestors as of 2026-06-30

303
funds hold it
0 of 35
superinvestors hold it
$2.65B
held by funds, at market
35.1%
of shares held by funds

Largest fund holders · TG THERAPEUTICS, INC.’s weight in each

iShares Core S&P Small-Cap ETF
IJR · iShares Trust
0.39%of fund net assets
VANGUARD TOTAL STOCK MARKET INDEX FUND
VTI · VANGUARD INDEX FUNDS
0.01%of fund net assets
iShares Russell 2000 ETF
IWM · iShares Trust
0.25%of fund net assets
VANGUARD SMALL-CAP INDEX FUND
VB · VANGUARD INDEX FUNDS
0.09%of fund net assets
1.09%of fund net assets

Fund ownership is a floor, not a census — pensions, insurers and people holding shares directly are not visible here.

Fund ownership counts N-PORT filers only, so it is a floor rather than a census — pensions, insurers and direct holders are not visible here, and the remainder is not “held by individuals”.

Every fund and institutional holder, quarter by quarter, is on the Ownership tab with a free account.

Connected research

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