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Companies / Health Care / X4 Pharmaceuticals, Inc
XFOR

X4 Pharmaceuticals, Inc

Health CareBiological Products
Ticker XFORBOSTON, MAFiscal year ends DecemberBook value per share $1.10Diluted shares 126.3M

X4 Pharmaceuticals, Inc. (Nasdaq: XFOR) is a biopharmaceutical company developing and commercializing therapeutics for rare hematology diseases. Its primary asset, mavorixafor, is an oral small-molecule antagonist of the CXCR4 receptor that promotes the mobilization of mature white blood cells from bone marrow into… From the company’s description.

Over the twelve months to Sep 30, 2026, X4 Pharmaceuticals, Inc reported revenue of $16.96M, down 50.1% from a year earlier, and a net loss of $80.52M. Its operating margin was −474.0%, and operations used $76.10M in cash. In fiscal 2025, it reported revenue of $35.11M, up 1273.2% from fiscal 2024, and a net loss of $79.20M.

Fiscal year 2025 · ends 12-31Changes are against fiscal 2024The amber dot is the latest twelve months, to 2026-09-30
Sales & profitability
$35.11MFY2025
+1273.2% year over year
Last 12 mo $16.96M
-247.44%FY2025
+1176.1 percentage points
Last 12 mo -473.95%
$-79.20MFY2025
−111.5% year over year
Last 12 mo $-80.52M
-42.51%FY2025
+126.6 percentage points
Last 12 mo -57.98%
Cash & financing
$-85.62MFY2025
+34.6% year over year
Last 12 mo $-76.10M
$-85.62MFY2025
+34.8% year over year
Last 12 mo $-76.10M
0.41FY2025
Was 3.41× a year earlier
Last 12 mo 0.55
42.3MFY2025
−79.0% year over year
Last 12 mo 126.3M

Margins and return on equity change in ; everything else in percent. Fewer shares and less debt are shown plainly, not as bad news — it depends what you make of buybacks. Dotted labels explain each measure. is shown separately from the annual figures.

What X4 Pharmaceuticals, Inc does

In the company’s own words

X4 Pharmaceuticals, Inc. (Nasdaq: XFOR) is a biopharmaceutical company developing and commercializing therapeutics for rare hematology diseases. Its primary asset, mavorixafor, is an oral small-molecule antagonist of the CXCR4 receptor that promotes the mobilization of mature white blood cells from bone marrow into the bloodstream. The company’s approved product, XOLREMDI (mavorixafor), is indicated in the United States for patients aged 12 and older with WHIM syndrome to increase circulating mature neutrophils and lymphocytes. Mavorixafor is also in a global Phase 3 trial for chronic neutropenia, with or without stable granulocyte colony-stimulating factor treatment. X4 makes XOLREMDI available in the United States and works with partners to commercialize or distribute it in international markets, including through Norgine in Europe, Australia and New Zealand. It relies on third-party contractors to manufacture its drug substance and finished product. The company reported $226.6 million in revenue for fiscal 2025. Its website is https://www.x4pharma.com/.

Company details
Sector
Health Care
Industry (SIC)
Biological Products
Headquarters
BOSTON, MA
Fiscal year end
December
CIK
1501697
SIC
2836

Financial performance, year by year

Fiscal 2018–2025 · USD
$-114.80M$-73.91M$-33.03M$7.86M$48.74M20182019202020212022202320242025Last 12 moLast 12 monthsLast 12 months

The full income statement, balance sheet and cash flow for each of these years — every figure traceable to its filing — is on the Financials tab with a free account.

Ownership

Who owns X4 Pharmaceuticals, Inc — and what changed

Funds as of 2026Q2 · superinvestors as of 2026-06-30

60
funds hold it
0 of 35
superinvestors hold it
$89.88M
held by funds, at market
19.8%
of shares held by funds

Largest fund holders · X4 Pharmaceuticals, Inc’s weight in each

Fidelity Small Cap Growth Fund
FCPGX · Fidelity Securities Fund
—of fund net assets
VANGUARD TOTAL STOCK MARKET INDEX FUND
VTI · VANGUARD INDEX FUNDS
0.00%of fund net assets
Inception Portfolio
MSSGX · MORGAN STANLEY INSTITUTIONAL FUND INC
3.82%of fund net assets
iShares Russell 2000 ETF
IWM · iShares Trust
0.01%of fund net assets
1.79%of fund net assets

Fund ownership is a floor, not a census — pensions, insurers and people holding shares directly are not visible here.

Fund ownership counts N-PORT filers only, so it is a floor rather than a census — pensions, insurers and direct holders are not visible here, and the remainder is not “held by individuals”.

Every fund and institutional holder, quarter by quarter, is on the Ownership tab with a free account.

Connected research

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