T. Rowe Price Health Sciences Fund, Inc.

T. ROWE PRICE HEALTH SCIENCES FUND, INC. · Series S000002088 · 2 share classes

Equity fund · 99% stocks· rate + credit risk filed
One fund, 2 share classes:PRHSXTHISX
$10.89B NAV
287 positions · as of 2026-03-31 · filed 2026-05-28
data updated 2026-08-10

Fund profile

As filed in the prospectus · 2026 Q1

The fund seeks long-term capital appreciation.

Strategy · summarised

The fund invests at least 80% of assets in common stocks of health sciences companies—pharmaceutical firms, biotechnology companies, medical device makers, and health care services providers—using fundamental bottom-up analysis to identify high-quality growth companies or, when valuations appear elevated, undervalued opportunities. The fund may also hold foreign stocks and recently public or privately held companies. Because the fund's allocation among the four health sciences areas varies with the adviser's outlook, its sector exposure will shift over time.

Expenses
0.67% 0.80%across 2 share classes
Share classExpense ratioAs of
PRHSX0.80%2025 Q1
THISX0.67%2025 Q1

Portfolio turnover 61.60% · as of 2026 Q1

Allocation

Asset groups · long / short shown separately, never netted · 2026 Q1

99.95%
of net assets
Stocks99.44%
Cash & short-term0.35%
Bonds0.17%

Latest quarter

What changed since the fund's previous filing

vs 2025Q4: 48 new42 exited

Largest new: ASTRAZENECA PLC, JNJ, AMGN, TENX, BELITE BIO INC - ADR, MRNA, ALMS, WST

Largest exited: ASTRAZENECA PLC-SPONS ADR, PEN, NBIX, BLUEJAY THERAPEUTICS SER C CVT PFD PP, WAT, ARCELLX INC, TENAX THERAPEUTICS PRE FUND WTS PIPE PP, TEVA

Return profile

Chart:

Total return as filed — price change plus distributions reinvested · trailing figures to Feb 2026

Share class1-year3-year5-yearVolWorst fall
Cumulative return· Apr 2023 – Feb 2026

Mar 2026 has been filed since the trailing figures were struck, so it is not in the table above or the curve — every figure here shares one cut-off, which is what makes them comparable with other funds.

Debt profile

What this fund holds — value-weighted across its bond and securitized long positions · as of 2026-03-31

Avg coupon
2.96%
Avg maturity
3.06 yr
Coupon type

Share of the fund's debt by how its coupon behaves — the fact that decides whether a rate move reaches this portfolio at all.

0%
floating
Fixed rate83.0%
Zero-coupon or unclassified17.0%
Maturity ladder

Share of the fund's debt value in each maturity band, shortest first.

<1y3-5y
<1y24.1%
3-5y75.9%
Flagged holdings
Defaulted: none reported
In arrears: none reported
Paid in kind: none reported

Based on what filers reported; a filer that never reported a flag also reads as none.

Risk profile

Interest-rate and credit-spread sensitivity, both in years · as of 2026Q1

This fund filed the credit-spread disclosure and reported no sensitivity — measured, and the answer is none.

Interest-rate duration
0.00 yr
approx. move per 100bp
Credit-spread duration
0.00 yr
approx. move per 100bp
Investment grade: +0.00 yrHigh yield: +0.00 yr
Show the numbers
TenorRate yrsIG yrsHY yrsIG $/bpHY $/bp
3 mo+0.00+0.00+0.00$0$0
1 yr+0.00+0.00+0.00$0$0
5 yr+0.00+0.00+0.00$0$0
10 yr+0.00+0.00+0.00$0$0
30 yr+0.00+0.00+0.00$0$0

Dollar change per 1bp of spread movement, as filed and sign-anchored. A blank cell was not filed; a zero was.

Holdings

By % of NAV · equity positions carry filed share counts · every resolvable issuer links to its company page

Issuer%NAVValue
ELI LILLY & COLLY10.14%$1.10B
THERMO FISHER SCIENTIFIC INCTMO4.07%$442.86M
INTUITIVE SURGICAL INCISRG3.65%$397.94M
STRYKER CORPSYK3.46%$377.06M
MERCK & CO. INC.MRK3.44%$374.87M
ASTRAZENECA PLC3.17%$345.38M
UNITEDHEALTH GROUP INCUNH3.09%$336.31M
ARGENX SE - ADRARGX2.92%$317.89M
ABBVIE INCABBV2.84%$309.56M
REGENERON PHARMACEUTICALSREGN2.65%$288.37M
Showing 10 of 287Sign in to see more

Top 10 positions are 39.42% of net assets, top 25 62.22%, across 287 issuers.

See more of this fund's book

More positions with filed share counts, and the quarter-over-quarter change list rather than the largest few — free with an account, no card required.

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