10x Insights
Loading account…
Companies / Health Care / Acrivon Therapeutics, Inc.
ACRV

Acrivon Therapeutics, Inc.

Health CarePharmaceutical Preparations
Ticker ACRVWATERTOWN, MAFiscal year ends DecemberBook value per share $2.15Diluted shares 40.3M

Acrivon Therapeutics, Inc. (Nasdaq: ACRV) is a clinical-stage biopharmaceutical company that discovers and develops precision medicines, initially focused on oncology. Its proprietary Acrivon Predictive Precision Proteomics (AP3) platform measures drug-regulated protein signaling to guide drug discovery, patient… From the company’s description.

In fiscal 2025, Acrivon Therapeutics, Inc. reported a net loss of $77.91M. Operations used $63.66M in cash.

Fiscal year 2025 · ends 12-31Changes are against fiscal 2024The amber dot is the latest twelve months, to 2026-06-30
Sales & profitability
—
0.00%FY2025
$-77.91MFY2025
+3.3% year over year
Last 12 mo $-74.22M
-69.24%FY2025
−23.7 percentage points
Last 12 mo -85.65%
Cash & financing
$-63.66MFY2025
+3.1% year over year
Last 12 mo $-62.92M
$-65.33MFY2025
+4.5% year over year
Last 12 mo $-64.14M
—
38.5MFY2025
+14.0% year over year
Last 12 mo 40.3M

Margins and return on equity change in ; everything else in percent. Fewer shares and less debt are shown plainly, not as bad news — it depends what you make of buybacks. Dotted labels explain each measure. is shown separately from the annual figures.

What Acrivon Therapeutics, Inc. does

In the company’s own words

Acrivon Therapeutics, Inc. (Nasdaq: ACRV) is a clinical-stage biopharmaceutical company that discovers and develops precision medicines, initially focused on oncology. Its proprietary Acrivon Predictive Precision Proteomics (AP3) platform measures drug-regulated protein signaling to guide drug discovery, patient selection and clinical development, while its OncoSignature tests use tumor biopsies to identify patients predicted to respond to specific drug candidates. Acrivon’s pipeline includes ACR-368, a CHK1/2 inhibitor being studied in solid tumors including endometrial cancer; ACR-2316, a dual WEE1/PKMYT1 inhibitor in Phase 1 development; and ACR-6840, a preclinical CDK11 inhibitor. The company also operates a CLIA-certified laboratory to support clinical testing. Acrivon was founded in 2018 and in-licensed ACR-368 from Eli Lilly; its other named drug candidates are internally discovered. It reports its business as a single operating segment. Its website is www.acrivon.com.

Company details
Sector
Health Care
Industry (SIC)
Pharmaceutical Preparations
Headquarters
WATERTOWN, MA
Fiscal year end
December
CIK
1781174
SIC
2834

Financial performance, year by year

Fiscal 2022–2025 · USD
$-85.49M$-70.68M$-55.86M$-41.04M$-26.23M2022202320242025Last 12 moLast 12 months

The full income statement, balance sheet and cash flow for each of these years — every figure traceable to its filing — is on the Financials tab with a free account.

Ownership

Who owns Acrivon Therapeutics, Inc. — and what changed

Funds as of 2026Q2 · superinvestors as of 2026-06-30

13
funds hold it
0 of 35
superinvestors hold it
$2.80M
held by funds, at market
3.7%
of shares held by funds

Largest fund holders · Acrivon Therapeutics, Inc.’s weight in each

VANGUARD TOTAL STOCK MARKET INDEX FUND
VTI · VANGUARD INDEX FUNDS
0.00%of fund net assets
VANGUARD EXTENDED MARKET INDEX FUND
VXF · VANGUARD INDEX FUNDS
0.00%of fund net assets
Ultra-Small Company Fund
BRUSX · Bridgeway Funds, Inc.
0.57%of fund net assets
Fidelity Extended Market Index Fund
FSMAX · Fidelity Concord Street Trust
—of fund net assets
iShares Micro-Cap ETF
IWC · iShares Trust
0.01%of fund net assets

Fund ownership is a floor, not a census — pensions, insurers and people holding shares directly are not visible here.

Fund ownership counts N-PORT filers only, so it is a floor rather than a census — pensions, insurers and direct holders are not visible here, and the remainder is not “held by individuals”.

Could not be determined for this company: bond issues.

Every fund and institutional holder, quarter by quarter, is on the Ownership tab with a free account.

Connected research

Put this business in context.

Compare this company with peers, find it in your funds and follow its financial history with your connected AI:

  • “How do Acrivon Therapeutics, Inc. and its peers compare on margins and cash generation over ten years?”
  • “Where did five years of Acrivon Therapeutics, Inc.'s earnings go — cash, debt, buybacks, reinvestment?”
  • “What changed in Acrivon Therapeutics, Inc.'s last four quarterly filings that the numbers alone won't show?”
See how it works →All research tools with a subscription. Use your own AI account.