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Companies / Health Care / Adaptive Biotechnologies Corp
ADPT

Adaptive Biotechnologies Corp

Health CareBiological Products
Ticker ADPTSEATTLE, WAFiscal year ends DecemberBook value per share $1.11Diluted shares 158.6M

Adaptive Biotechnologies Corporation (Nasdaq: ADPT) develops and commercializes products and services based on sequencing and interpreting the adaptive immune system. Its clonoSEQ test measures minimal residual disease in patients with lymphoid cancers, helping clinicians monitor disease and assess treatment response;… From the company’s description.

Over the twelve months to Sep 30, 2026, Adaptive Biotechnologies Corp reported revenue of $298.01M, up 17.9% from a year earlier, and a net loss of $70.73M. Its operating margin was −16.2%, and operations used $4.28M in cash. In fiscal 2025, it reported revenue of $276.98M, up 54.8% from fiscal 2024, and a net loss of $59.46M.

Fiscal year 2025 · ends 12-31Changes are against fiscal 2024The amber dot is the latest twelve months, to 2026-09-30
Sales & profitability
$276.98MFY2025
+54.8% year over year
Last 12 mo $298.01M
-20.62%FY2025
+70.2 percentage points
Last 12 mo -16.18%
$-59.46MFY2025
+62.7% year over year
Last 12 mo $-70.73M
-27.19%FY2025
+51.5 percentage points
Last 12 mo -40.02%
Cash & financing
$-45.99MFY2025
+51.7% year over year
Last 12 mo $-4.28M
$-48.95MFY2025
+50.5% year over year
Last 12 mo $-8.82M
0.60FY2025
Was 0.66× a year earlier
Last 12 mo 1.90
151.7MFY2025
+3.1% year over year
Last 12 mo 158.6M

Margins and return on equity change in ; everything else in percent. Fewer shares and less debt are shown plainly, not as bad news — it depends what you make of buybacks. Dotted labels explain each measure. is shown separately from the annual figures.

What Adaptive Biotechnologies Corp does

In the company’s own words

Adaptive Biotechnologies Corporation (Nasdaq: ADPT) develops and commercializes products and services based on sequencing and interpreting the adaptive immune system. Its clonoSEQ test measures minimal residual disease in patients with lymphoid cancers, helping clinicians monitor disease and assess treatment response; the company also provides the assay to biopharmaceutical partners for use in clinical trials. Its Immune Medicine business offers immune-receptor sequencing, data licensing, T-cell receptor–antigen prediction models and target discovery services to research and biopharmaceutical customers. The company is organized into two businesses: MRD, comprising clinical testing and MRD Pharma, and Immune Medicine, which applies its immune-receptor data and technologies to research and product development. In 2025, revenue was $277.0 million, including $212.3 million from MRD. During that year, clonoSEQ was used in more than 180 active trials conducted by over 40 biopharmaceutical partners. The company’s proprietary datasets include more than five million T-cell receptor–antigen matches.

Company details
Sector
Health Care
Industry (SIC)
Biological Products
Headquarters
SEATTLE, WA
Fiscal year end
December
CIK
1478320
SIC
2836

Financial performance, year by year

Fiscal 2019–2025 · USD
$-277.64M$-120.64M$36.35M$193.35M$350.34M2019202020212022202320242025Last 12 moLast 12 monthsLast 12 months

The full income statement, balance sheet and cash flow for each of these years — every figure traceable to its filing — is on the Financials tab with a free account.

Ownership

Who owns Adaptive Biotechnologies Corp — and what changed

Funds as of 2026Q2 · superinvestors as of 2026-06-30

275
funds hold it
1 of 35
superinvestors hold it
$1.01B
held by funds, at market
33.1%
of shares held by funds
1
bond issues held by funds

Superinvestors in Adaptive Biotechnologies Corp · what they did last quarter

Polen CapitalDECREASED -11.7%
Polen Capital Management
<0.1%of 13F portfolio

Share of each manager’s reported 13F portfolio. Change is in shares held, since the previous quarter.

Largest fund holders · Adaptive Biotechnologies Corp’s weight in each

VANGUARD TOTAL STOCK MARKET INDEX FUND
VTI · VANGUARD INDEX FUNDS
0.00%of fund net assets
iShares Russell 2000 ETF
IWM · iShares Trust
0.10%of fund net assets
VANGUARD SMALL-CAP INDEX FUND
VB · VANGUARD INDEX FUNDS
0.02%of fund net assets
0.20%of fund net assets
VANGUARD EXTENDED MARKET INDEX FUND
VXF · VANGUARD INDEX FUNDS
0.03%of fund net assets

Fund ownership is a floor, not a census — pensions, insurers and people holding shares directly are not visible here.

Adaptive Biotechnologies Corp’s bonds, as funds hold them

Funds report holding 1 issues of Adaptive Biotechnologies Corp’s debt, $1.98M at market value — what funds hold, not the company’s total debt.

Fund ownership counts N-PORT filers only, so it is a floor rather than a census — pensions, insurers and direct holders are not visible here, and the remainder is not “held by individuals”.

Fund ownership is a subset of institutional 13F ownership — the two describe overlapping populations and must not be added together.

Every fund and institutional holder, quarter by quarter, is on the Ownership tab with a free account.

Connected research

Put this business in context.

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