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Companies / Healthcare / Adicet Bio, Inc.
ACET

Adicet Bio, Inc.

HealthcarePharmaceutical Preparations
Ticker ACETBOSTON, MAFiscal year ends DecemberBook value per share $11.18Diluted shares 10.7M

Adicet Bio, Inc. (Nasdaq Capital Market: ACET) is a clinical-stage biotechnology company focused on discovering and developing allogeneic gamma delta T cell therapies for autoimmune diseases and cancer. The company's website is www.adicetbio.com. From the company’s description.

Fiscal year 2025 · ends 12-26Changes are against fiscal 2024The amber dot is the latest twelve months, to 2026-06-30
Sales & profitability
—
0.00%
$-116.80M
+0.3% year over year
Last 12 mo $-98.97M
-73.36%
−10.6 percentage points
Last 12 mo -82.38%
Cash & financing
$-95.25M
−3.1% year over year
Last 12 mo $-84.53M
$-96.98M
−3.7% year over year
Last 12 mo $-84.97M
0.01
Last 12 mo 0.01
6.9M
−92.2% year over year
Last 12 mo 10.7M

Margins and return on equity change in ; everything else in percent. Fewer shares and less debt are shown plainly, not as bad news — it depends what you make of buybacks. Dotted labels explain each measure. is shown separately from the annual figures.

What Adicet Bio, Inc. does

In the company’s own words

Adicet Bio, Inc. (Nasdaq Capital Market: ACET) is a clinical-stage biotechnology company focused on discovering and developing allogeneic gamma delta T cell therapies for autoimmune diseases and cancer. The company's website is www.adicetbio.com.

The company's core approach centers on engineering "off-the-shelf" gamma delta T cells derived from peripheral blood cells of unrelated donors, allowing rapid and cost-efficient product candidate generation. This allogeneic manufacturing process enables products to be stored and administered on demand without inducing graft-versus-host immune responses, contrasting with autologous alpha beta T cell therapies that require individualized manufacturing for each patient.

Adicet's lead product candidate, prulacabtagene leucel (prula-cel, formerly ADI-001), is a first-in-class allogeneic gamma delta T cell therapy expressing a chimeric antigen receptor targeting CD20, currently in Phase 1 clinical development across multiple autoimmune indications including lupus nephritis, systemic lupus erythematosus, systemic sclerosis, antineutrophil cytoplasmic autoantibody-associated vasculitis, idiopathic inflammatory myopathy, stiff person syndrome, and rheumatoid arthritis. The FDA granted Fast Track Designation for prula-cel in lupus nephritis and systemic lupus erythematosus with extrarenal involvement, as well as systemic sclerosis.

The company is also advancing ADI-212, a next-generation gene-edited and armored clinical candidate designed to target prostate-specific membrane antigen for metastatic castration-resistant prostate cancer treatment. ADI-212 integrates membrane-tethered IL-12 armoring and CRISPR/Cas9-mediated disruption of the mediator complex to enhance potency in solid tumors.

Adicet maintains strategic collaborations with Regeneron Pharmaceuticals for antigen binding domain development, CRISPR Therapeutics for gene-editing technology, Twist Bioscience for antibody discovery, and the City of Hope for licensing arrangements. The company's intellectual property portfolio includes multiple granted patents and pending applications covering gamma delta T cell expansion platforms, manufacturing processes, and specific product candidates, with patent protection extending through the 2030s and 2040s.

Company details
Sector
Healthcare
Industry
Pharmaceutical Preparations
Headquarters
BOSTON, MA
Fiscal year end
December
CIK
1720580
SIC
2834

Financial performance, year by year

Fiscal 2018–2025 · USD
$-159.42M$-109.13M$-58.83M$-8.54M$41.75M20182019202020212022202320242025Last 12 moLast 12 months

The full income statement, balance sheet and cash flow for each of these years — every figure traceable to its filing — is on the Financials tab with a free account.

Ownership

Who owns Adicet Bio, Inc. — and what changed

Funds as of 2026Q2 · superinvestors as of 2026-06-30

15
funds hold it
0 of 35
superinvestors hold it
$6.52M
held by funds, at market
8.3%
of shares held by funds

Largest fund holders · Adicet Bio, Inc.’s weight in each

VANGUARD TOTAL STOCK MARKET INDEX FUND
VTI · VANGUARD INDEX FUNDS
0.00%of fund net assets
Franklin Biotechnology Discovery Fund
FBDIX · Franklin Strategic Series
0.16%of fund net assets
VANGUARD EXTENDED MARKET INDEX FUND
VXF · VANGUARD INDEX FUNDS
0.00%of fund net assets
Ultra-Small Company Fund
BRUSX · Bridgeway Funds, Inc.
0.75%of fund net assets
Fidelity Extended Market Index Fund
FSMAX · Fidelity Concord Street Trust
0.00%of fund net assets

Fund ownership is a floor, not a census — pensions, insurers and people holding shares directly are not visible here.

Fund ownership counts N-PORT filers only, so it is a floor rather than a census — pensions, insurers and direct holders are not visible here, and the remainder is not “held by individuals”.

Every fund and institutional holder, quarter by quarter, is on the Ownership tab with a free account.

Connected research

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