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Companies / Health Care / Akebia Therapeutics, Inc.
AKBA

Akebia Therapeutics, Inc.

Health CarePharmaceutical Preparations
Ticker AKBAWALTHAM, MAFiscal year ends DecemberBook value per share $0.08Diluted shares 271.2M

Akebia Therapeutics, Inc. (Nasdaq: AKBA) is a biopharmaceutical company that develops and commercializes medicines for kidney disease and related conditions. Its commercial products are Vafseo (vadadustat), an oral treatment for anemia due to chronic kidney disease in adults on dialysis, and Auryxia (ferric citrate),… From the company’s description.

Over the twelve months to Sep 30, 2026, Akebia Therapeutics, Inc. reported revenue of $197.20M, down 12.4% from a year earlier, and a net loss of $44.56M. Its operating margin was −15.7%, and operations generated $15.78M in cash. In fiscal 2025, it reported revenue of $236.20M, up 47.5% from fiscal 2024, and a net loss of $5.34M.

Fiscal year 2025 · ends 12-31Changes are against fiscal 2024The amber dot is the latest twelve months, to 2026-09-30
Sales & profitability
$236.20MFY2025
+47.5% year over year
Last 12 mo $197.20M
9.95%FY2025
+41.5 percentage points
Last 12 mo -15.74%
$-5.34MFY2025
+92.3% year over year
Last 12 mo $-44.56M
-16.39%FY2025
−157.5 percentage points
Last 12 mo -203.14%
Cash & financing
$67.99MFY2025
+267.2% year over year
Last 12 mo $15.78M
$67.70MFY2025
+266.4% year over year
Last 12 mo $13.86M
1.48FY2025
Was -0.79× a year earlier
Last 12 mo 2.47
257.2MFY2025
+21.9% year over year
Last 12 mo 271.2M

Margins and return on equity change in ; everything else in percent. Fewer shares and less debt are shown plainly, not as bad news — it depends what you make of buybacks. Dotted labels explain each measure. is shown separately from the annual figures.

What Akebia Therapeutics, Inc. does

In the company’s own words

Akebia Therapeutics, Inc. (Nasdaq: AKBA) is a biopharmaceutical company that develops and commercializes medicines for kidney disease and related conditions. Its commercial products are Vafseo (vadadustat), an oral treatment for anemia due to chronic kidney disease in adults on dialysis, and Auryxia (ferric citrate), an oral medicine for elevated phosphorus in adults on dialysis and iron deficiency anemia in adults with non-dialysis-dependent kidney disease. The company also develops treatments for rare kidney diseases and other indications, including praliciguat for focal segmental glomerulosclerosis, AKB-097 for complement-mediated kidney diseases, and early-stage HIF-based candidates. Akebia markets both commercial products in the United States, while partners market Vafseo and ferric citrate in certain countries abroad. Its portfolio includes the Auryxia, Vafseo and AKEBIA Therapeutics brands. Auryxia joined the portfolio through Akebia’s 2018 merger with Keryx Biopharmaceuticals. For the fiscal year ended December 31, 2025, the company reported $[revenue figure not provided] in revenue. Its website is www.akebia.com.

Company details
Sector
Health Care
Industry (SIC)
Pharmaceutical Preparations
Headquarters
WALTHAM, MA
Fiscal year end
December
CIK
1517022
SIC
2834

Financial performance, year by year

Fiscal 2014–2025 · USD
$-455.30M$-239.77M$-24.23M$191.31M$406.85M201420152016201720182019202020212022202320242025Last 12 moLast 12 monthsLast 12 months

The full income statement, balance sheet and cash flow for each of these years — every figure traceable to its filing — is on the Financials tab with a free account.

Ownership

Who owns Akebia Therapeutics, Inc. — and what changed

Funds as of 2026Q2 · superinvestors as of 2026-06-30

136
funds hold it
0 of 35
superinvestors hold it
$48.81M
held by funds, at market
15.2%
of shares held by funds

Largest fund holders · Akebia Therapeutics, Inc.’s weight in each

VANGUARD TOTAL STOCK MARKET INDEX FUND
VTI · VANGUARD INDEX FUNDS
0.00%of fund net assets
iShares Russell 2000 ETF
IWM · iShares Trust
0.01%of fund net assets
VANGUARD EXTENDED MARKET INDEX FUND
VXF · VANGUARD INDEX FUNDS
0.00%of fund net assets
Fidelity Small Cap Index Fund
FSSNX · Fidelity Salem Street Trust
—of fund net assets
0.02%of fund net assets

Fund ownership is a floor, not a census — pensions, insurers and people holding shares directly are not visible here.

Fund ownership counts N-PORT filers only, so it is a floor rather than a census — pensions, insurers and direct holders are not visible here, and the remainder is not “held by individuals”.

Every fund and institutional holder, quarter by quarter, is on the Ownership tab with a free account.

Connected research

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