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Companies / Health Care / Alto Neuroscience, Inc.
ANRO

Alto Neuroscience, Inc.

Health CarePharmaceutical Preparations
Ticker ANROMOUNTAIN VIEW, CAFiscal year ends DecemberBook value per share $5.46Diluted shares 40.2M

Alto Neuroscience, Inc. (NYSE: ANRO) is a clinical-stage biopharmaceutical company developing treatments for neuropsychiatric conditions using its Precision Psychiatry Platform to identify biomarkers that may help predict patient response. The platform combines neurocognitive assessments, EEG, wearable-device, genetic… From the company’s description.

In fiscal 2025, Alto Neuroscience, Inc. reported a net loss of $63.24M. Operations used $51.77M in cash.

Fiscal year 2025 · ends 12-31Changes are against fiscal 2024The amber dot is the latest twelve months, to 2026-06-30
Sales & profitability
—
0.00%FY2025
$-63.24MFY2025
−2.9% year over year
Last 12 mo $-84.24M
-41.84%FY2025
−1.3 percentage points
Last 12 mo -38.42%
Cash & financing
$-51.77MFY2025
−9.2% year over year
Last 12 mo $-68.28M
$-51.79MFY2025
−4.6% year over year
Last 12 mo $-68.84M
0.13FY2025
Was 0.08× a year earlier
Last 12 mo 0.09
28.9MFY2025
+17.3% year over year
Last 12 mo 40.2M

Margins and return on equity change in ; everything else in percent. Fewer shares and less debt are shown plainly, not as bad news — it depends what you make of buybacks. Dotted labels explain each measure. is shown separately from the annual figures.

What Alto Neuroscience, Inc. does

In the company’s own words

Alto Neuroscience, Inc. (NYSE: ANRO) is a clinical-stage biopharmaceutical company developing treatments for neuropsychiatric conditions using its Precision Psychiatry Platform to identify biomarkers that may help predict patient response. The platform combines neurocognitive assessments, EEG, wearable-device, genetic and genomic data with quantitative analytics, including machine learning. Its seven clinical-stage assets address major depressive disorder, bipolar depression, treatment-resistant depression, schizophrenia and Parkinson’s disease. Candidates include ALTO-207, a fixed-dose pramipexole and ondansetron combination for treatment-resistant depression; ALTO-300, an investigational antidepressant for biomarker-selected patients with major depressive disorder; and ALTO-101, a transdermal PDE4 inhibitor being studied for cognitive impairment associated with schizophrenia. Alto also develops candidates for bipolar depression and other indications. The company was founded in 2019 and acquired ALTO-207 and ALTO-208, a pramipexole and aprepitant combination for Parkinson’s disease, from Chase Therapeutics in 2025. Biomarker collection through its platform has involved more than 70 clinical sites and over 2,000 participants. Its website is https://www.altoneuroscience.com.

Company details
Sector
Health Care
Industry (SIC)
Pharmaceutical Preparations
Headquarters
MOUNTAIN VIEW, CA
Fiscal year end
December
CIK
1999480
SIC
2834

Financial performance, year by year

Fiscal 2024–2025 · USD
$-86.52M$-79.68M$-72.83M$-65.99M$-59.15M20242025Last 12 moLast 12 months

The full income statement, balance sheet and cash flow for each of these years — every figure traceable to its filing — is on the Financials tab with a free account.

Ownership

Who owns Alto Neuroscience, Inc. — and what changed

Funds as of 2026Q2 · superinvestors as of 2026-06-30

84
funds hold it
0 of 35
superinvestors hold it
$109.44M
held by funds, at market
10.8%
of shares held by funds

Largest fund holders · Alto Neuroscience, Inc.’s weight in each

VANGUARD TOTAL STOCK MARKET INDEX FUND
VTI · VANGUARD INDEX FUNDS
0.00%of fund net assets
iShares Russell 2000 ETF
IWM · iShares Trust
0.02%of fund net assets
Franklin Biotechnology Discovery Fund
FBDIX · Franklin Strategic Series
—of fund net assets
VANGUARD EXTENDED MARKET INDEX FUND
VXF · VANGUARD INDEX FUNDS
0.01%of fund net assets
0.04%of fund net assets

Fund ownership is a floor, not a census — pensions, insurers and people holding shares directly are not visible here.

Fund ownership counts N-PORT filers only, so it is a floor rather than a census — pensions, insurers and direct holders are not visible here, and the remainder is not “held by individuals”.

Could not be determined for this company: bond issues.

Every fund and institutional holder, quarter by quarter, is on the Ownership tab with a free account.

Connected research

Put this business in context.

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