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Companies / Health Care / AN2 Therapeutics, Inc.
ANTX

AN2 Therapeutics, Inc.

Health CarePharmaceutical Preparations
Ticker ANTXMENLO PARK, CAFiscal year ends DecemberBook value per share $1.92Diluted shares 39.4M

AN2 Therapeutics (Nasdaq: ANTX) is a clinical-stage biopharmaceutical company discovering and developing small-molecule therapeutics using its boron chemistry platform. Its pipeline addresses hematologic diseases, infectious diseases and oncology, with clinical programs including epetraborole for polycythemia vera and… From the company’s description.

In fiscal 2025, AN2 Therapeutics, Inc. reported a net loss of $35.17M. Operations used $29.83M in cash.

Fiscal year 2025 · ends 12-31Changes are against fiscal 2024The amber dot is the latest twelve months, to 2026-06-30
Sales & profitability
—
0.00%FY2025
$-35.17MFY2025
+31.5% year over year
Last 12 mo $-36.28M
-66.29%FY2025
−3.6 percentage points
Last 12 mo -47.78%
Cash & financing
$-29.83MFY2025
+39.4% year over year
Last 12 mo $-30.68M
$-29.83MFY2025
+39.4% year over year
Last 12 mo $-30.68M
—
30.2MFY2025
+1.3% year over year
Last 12 mo 39.4M

Margins and return on equity change in ; everything else in percent. Fewer shares and less debt are shown plainly, not as bad news — it depends what you make of buybacks. Dotted labels explain each measure. is shown separately from the annual figures.

What AN2 Therapeutics, Inc. does

In the company’s own words

AN2 Therapeutics (Nasdaq: ANTX) is a clinical-stage biopharmaceutical company discovering and developing small-molecule therapeutics using its boron chemistry platform. Its pipeline addresses hematologic diseases, infectious diseases and oncology, with clinical programs including epetraborole for polycythemia vera and Mycobacterium abscessus complex lung disease, and AN2-502998 for Chagas disease. Research programs include preclinical candidates targeting PI3Kα and ENPP1 in oncology, as well as work in bone disorders and infectious diseases. The company’s global health programs include melioidosis and tuberculosis, supported primarily by grants and partnerships. AN2 licenses epetraborole in China, Hong Kong, Taiwan and Macau to Brii Biosciences, which is responsible for development and commercialization in those territories. The company relies on third-party manufacturers for materials and drug products used in preclinical studies and clinical trials. It was founded around a boron-based drug discovery approach, with licensed compounds and intellectual property underpinning its development programs. Its website is https://www.an2therapeutics.com/.

Company details
Sector
Health Care
Industry (SIC)
Pharmaceutical Preparations
Headquarters
MENLO PARK, CA
Fiscal year end
December
CIK
1880438
SIC
2834

Financial performance, year by year

Fiscal 2022–2025 · USD
$-67.69M$-58.82M$-49.95M$-41.09M$-32.22M2022202320242025Last 12 moLast 12 months

The full income statement, balance sheet and cash flow for each of these years — every figure traceable to its filing — is on the Financials tab with a free account.

Ownership

Who owns AN2 Therapeutics, Inc. — and what changed

Funds as of 2026Q2 · superinvestors as of 2026-06-30

48
funds hold it
0 of 35
superinvestors hold it
$12.90M
held by funds, at market
7.1%
of shares held by funds

Largest fund holders · AN2 Therapeutics, Inc.’s weight in each

VANGUARD TOTAL STOCK MARKET INDEX FUND
VTI · VANGUARD INDEX FUNDS
0.00%of fund net assets
iShares Russell 2000 ETF
IWM · iShares Trust
0.00%of fund net assets
VANGUARD EXTENDED MARKET INDEX FUND
VXF · VANGUARD INDEX FUNDS
0.00%of fund net assets
iShares Russell 2000 Value ETF
IWN · iShares Trust
0.01%of fund net assets
Fidelity Extended Market Index Fund
FSMAX · Fidelity Concord Street Trust
—of fund net assets

Fund ownership is a floor, not a census — pensions, insurers and people holding shares directly are not visible here.

Fund ownership counts N-PORT filers only, so it is a floor rather than a census — pensions, insurers and direct holders are not visible here, and the remainder is not “held by individuals”.

Could not be determined for this company: bond issues.

Every fund and institutional holder, quarter by quarter, is on the Ownership tab with a free account.

Connected research

Put this business in context.

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