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Companies / Health Care / Artiva Biotherapeutics, Inc.
ARTV

Artiva Biotherapeutics, Inc.

Health CareBiological Products
Ticker ARTVSAN DIEGO, CAFiscal year ends DecemberBook value per share $10.83Diluted shares 32.1M

Artiva Biotherapeutics, Inc. (Nasdaq: ARTV) is a clinical-stage biotechnology company focused on developing natural killer cell-based therapies for patients with autoimmune diseases and cancers. The company's website is www.artivabiotherapeutics.com. From the company’s description.

Fiscal year 2025 · ends 12-31Changes are against fiscal 2024The amber dot is the latest twelve months, to 2026-06-30
Sales & profitability
$0.00M
−100.0% year over year
0.00%
$-83.86M
−28.3% year over year
Last 12 mo $-90.82M
-76.26%
−41.2 percentage points
Last 12 mo -26.14%
Cash & financing
$-76.75M
−39.5% year over year
Last 12 mo $-75.23M
$-79.34M
−42.5% year over year
Last 12 mo $-76.91M
0.00
Was 0.00× a year earlier
24.4M
+117.1% year over year
Last 12 mo 32.1M

Margins and return on equity change in ; everything else in percent. Fewer shares and less debt are shown plainly, not as bad news — it depends what you make of buybacks. Dotted labels explain each measure. is shown separately from the annual figures.

What Artiva Biotherapeutics, Inc. does

In the company’s own words

Artiva Biotherapeutics, Inc. (Nasdaq: ARTV) is a clinical-stage biotechnology company focused on developing natural killer cell-based therapies for patients with autoimmune diseases and cancers. The company's website is www.artivabiotherapeutics.com.

The company's lead product candidate, AlloNK (also known as AB-101), is an allogeneic, non-genetically modified, cryopreserved NK cell therapy designed to enhance antibody-dependent cellular cytotoxicity to drive B-cell depletion. AlloNK is currently being evaluated in three ongoing clinical trials for B-cell driven autoimmune diseases, with refractory rheumatoid arthritis designated as the lead indication. The company is also pursuing CAR-NK product candidates through collaborator-funded trials, including AB-201, a HER2-targeting CAR-NK cell product candidate, and AB-205, a CD5-directed CAR-NK cell product candidate.

Artiva was founded in 2019 as a spinout of GC Cell Corporation, a South Korean healthcare company with over two decades of cell therapy research and manufacturing experience. The strategic partnership grants Artiva exclusive worldwide rights, excluding Asia, Australia and New Zealand, to GC Cell's NK cell manufacturing technology and programs. This manufacturing-first approach provides Artiva with a mature, scalable production process established before clinical development commenced.

The company operates a 9,000 square foot, current Good Manufacturing Practices-compliant cell production center at its San Diego headquarters. Artiva has manufactured over 50 clinical batches of AlloNK and demonstrated batch-to-batch and donor-to-donor consistency. The estimated cost of goods sold for AlloNK per patient in commercial settings would be below $3,000 to $12,000, approximately an order of magnitude lower than autologous CAR-T therapies.

As of October 1, 2025, 32 patients with autoimmune disease had been treated with AlloNK plus anti-CD20 monoclonal antibody across multiple indications. AlloNK has received Fast Track designation from the FDA in refractory rheumatoid arthritis and lupus nephritis. The company's approach aims to address limitations of existing cell therapies through improved scalability, enhanced safety profile, reduced cost, and the ability to administer treatment in community outpatient settings rather than specialized clinical centers.

Company details
Sector
Health Care
Industry (SIC)
Biological Products
Headquarters
SAN DIEGO, CA
Fiscal year end
December
CIK
1817241
SIC
2836

Financial performance, year by year

Fiscal 2024–2025 · USD
$-99.93M$-72.61M$-45.29M$-17.96M$9.36M20242025Last 12 moLast 12 months

The full income statement, balance sheet and cash flow for each of these years — every figure traceable to its filing — is on the Financials tab with a free account.

Ownership

Who owns Artiva Biotherapeutics, Inc. — and what changed

Funds as of 2026Q2 · superinvestors as of 2026-06-30

50
funds hold it
0 of 35
superinvestors hold it
$16.87M
held by funds, at market
3.6%
of shares held by funds

Largest fund holders · Artiva Biotherapeutics, Inc.’s weight in each

VANGUARD TOTAL STOCK MARKET INDEX FUND
VTI · VANGUARD INDEX FUNDS
0.00%of fund net assets
VANGUARD EXTENDED MARKET INDEX FUND
VXF · VANGUARD INDEX FUNDS
0.00%of fund net assets
Franklin Biotechnology Discovery Fund
FBDIX · Franklin Strategic Series
0.19%of fund net assets
iShares Russell 2000 ETF
IWM · iShares Trust
0.00%of fund net assets
Simplify Propel Opportunities ETF
SURI · Simplify Exchange Traded Funds
1.27%of fund net assets

Fund ownership is a floor, not a census — pensions, insurers and people holding shares directly are not visible here.

Fund ownership counts N-PORT filers only, so it is a floor rather than a census — pensions, insurers and direct holders are not visible here, and the remainder is not “held by individuals”.

Could not be determined for this company: bond issues.

Every fund and institutional holder, quarter by quarter, is on the Ownership tab with a free account.

Connected research

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