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Companies / Health Care / Arvinas, Inc.
ARVN

Arvinas, Inc.

Health CarePharmaceutical Preparations
Ticker ARVNNEW HAVEN, CTFiscal year ends DecemberBook value per share $7.82Diluted shares 65.7M

Arvinas, Inc. (Nasdaq: ARVN) is a clinical-stage biotechnology company developing medicines through its PROTAC protein-degradation platform, which is designed to harness the body’s protein-disposal system to remove disease-causing proteins. Its clinical programs address oncology and neurology: vepdegestrant targets… From the company’s description.

Over the twelve months to Sep 30, 2026, Arvinas, Inc. reported revenue of $275.30M, down 11.8% from a year earlier, and a net loss of $9.50M. Its operating margin was −12.1%, and operations used $158.30M in cash. In fiscal 2025, it reported revenue of $262.60M, down 0.3% from fiscal 2024, and a net loss of $80.80M.

Fiscal year 2025 · ends 12-31Changes are against fiscal 2024The amber dot is the latest twelve months, to 2026-09-30
Sales & profitability
$262.60MFY2025
−0.3% year over year
Last 12 mo $275.30M
-45.13%FY2025
+49.9 percentage points
Last 12 mo -12.13%
$-80.80MFY2025
+59.4% year over year
Last 12 mo $-9.50M
-18.62%FY2025
+16.8 percentage points
Last 12 mo -1.85%
Cash & financing
$-273.80MFY2025
−5.6% year over year
Last 12 mo $-158.30M
$-275.70MFY2025
−5.6% year over year
Last 12 mo $-159.80M
0.00FY2025
Was 0.00× a year earlier
Last 12 mo 0.00
70.9MFY2025
−1.4% year over year
Last 12 mo 65.7M

Margins and return on equity change in ; everything else in percent. Fewer shares and less debt are shown plainly, not as bad news — it depends what you make of buybacks. Dotted labels explain each measure. is shown separately from the annual figures.

What Arvinas, Inc. does

In the company’s own words

Arvinas, Inc. (Nasdaq: ARVN) is a clinical-stage biotechnology company developing medicines through its PROTAC protein-degradation platform, which is designed to harness the body’s protein-disposal system to remove disease-causing proteins. Its clinical programs address oncology and neurology: vepdegestrant targets the estrogen receptor in advanced breast cancer; ARV-102 targets LRRK2 for neurodegenerative diseases including Parkinson’s disease; ARV-806 targets KRAS G12D in solid tumors; ARV-393 targets BCL6 in non-Hodgkin lymphoma; and ARV-027 targets expanded androgen receptor in skeletal muscle. The company also advances preclinical programs, including a HPK1 candidate and a pan-KRAS degrader, and conducts research collaborations with Pfizer and Genentech. Its intended beneficiaries are patients with cancer and neurological or neuromuscular diseases, with development and commercialization activities also involving collaborators and other third parties. The FDA has accepted the company’s application for vepdegestrant, its most advanced candidate, with an action date of June 5, 2026.

Company details
Sector
Health Care
Industry (SIC)
Pharmaceutical Preparations
Headquarters
NEW HAVEN, CT
Fiscal year end
December
CIK
1655759
SIC
2834

Financial performance, year by year

Fiscal 2018–2025 · USD
$-431.56M$-238.78M$-46.00M$146.78M$339.56M20182019202020212022202320242025Last 12 moLast 12 monthsLast 12 months

The full income statement, balance sheet and cash flow for each of these years — every figure traceable to its filing — is on the Financials tab with a free account.

Ownership

Who owns Arvinas, Inc. — and what changed

Funds as of 2026Q2 · superinvestors as of 2026-06-30

201
funds hold it
0 of 35
superinvestors hold it
$161.02M
held by funds, at market
28.1%
of shares held by funds

Largest fund holders · Arvinas, Inc.’s weight in each

VANGUARD TOTAL STOCK MARKET INDEX FUND
VTI · VANGUARD INDEX FUNDS
0.00%of fund net assets
VANGUARD STRATEGIC EQUITY FUND
VSEQX · VANGUARD HORIZON FUNDS
0.12%of fund net assets
iShares Russell 2000 ETF
IWM · iShares Trust
0.02%of fund net assets
—of fund net assets
VANGUARD EXTENDED MARKET INDEX FUND
VXF · VANGUARD INDEX FUNDS
0.01%of fund net assets

Fund ownership is a floor, not a census — pensions, insurers and people holding shares directly are not visible here.

Fund ownership counts N-PORT filers only, so it is a floor rather than a census — pensions, insurers and direct holders are not visible here, and the remainder is not “held by individuals”.

Could not be determined for this company: bond issues.

Every fund and institutional holder, quarter by quarter, is on the Ownership tab with a free account.

Connected research

Put this business in context.

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