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Companies / Health Care / Cadrenal Therapeutics, Inc.
CVKD

Cadrenal Therapeutics, Inc.

Health CarePharmaceutical Preparations
Ticker CVKDPONTE VEDRA, FLFiscal year ends DecemberBook value per share $1.54Diluted shares 2.7M

Cadrenal Therapeutics, Inc. (Nasdaq: CVKD) is a clinical-stage biopharmaceutical company developing therapies for immune and thrombotic conditions. Its lead candidate, CAD-1005, is a selective 12-lipoxygenase inhibitor in development for heparin-induced thrombocytopenia; the company is preparing a pivotal Phase 3… From the company’s description.

In fiscal 2025, Cadrenal Therapeutics, Inc. reported a net loss of $13.24M. Operations used $12.60M in cash.

Fiscal year 2025 · ends 12-31Changes are against fiscal 2024The amber dot is the latest twelve months, to 2026-06-30
Sales & profitability
—
0.00%FY2025
$-13.24MFY2025
−24.3% year over year
Last 12 mo $-11.54M
-483.34%FY2025
−339.5 percentage points
Last 12 mo -282.09%
Cash & financing
$-12.60MFY2025
−71.3% year over year
Last 12 mo $-10.16M
$-12.61MFY2025
−71.2% year over year
Last 12 mo $-10.16M
—
2.0MFY2025
+63.5% year over year
Last 12 mo 2.7M

Margins and return on equity change in ; everything else in percent. Fewer shares and less debt are shown plainly, not as bad news — it depends what you make of buybacks. Dotted labels explain each measure. is shown separately from the annual figures.

What Cadrenal Therapeutics, Inc. does

In the company’s own words

Cadrenal Therapeutics, Inc. (Nasdaq: CVKD) is a clinical-stage biopharmaceutical company developing therapies for immune and thrombotic conditions. Its lead candidate, CAD-1005, is a selective 12-lipoxygenase inhibitor in development for heparin-induced thrombocytopenia; the company is preparing a pivotal Phase 3 trial following an end-of-Phase 2 meeting with the FDA. Its pipeline also includes tecarfarin, an oral vitamin K antagonist for chronic anticoagulation, with development focused on patients with kidney dysfunction or left ventricular assist devices, and frunexian, an intravenous Factor XIa inhibitor designed for acute-care settings. Cadrenal acquired the CAD-1005 program and related 12-LOX assets from Veralox Therapeutics in December 2025, shifting its primary strategic focus to that platform. Tecarfarin has been studied in 11 clinical trials involving more than 1,000 individuals, while frunexian is Phase 2-ready. The company’s candidates target hospital and chronic-care needs, including prevention of blood clots in patients requiring anticoagulation.

Company details
Sector
Health Care
Industry (SIC)
Pharmaceutical Preparations
Headquarters
PONTE VEDRA, FL
Fiscal year end
December
CIK
1937993
SIC
2834

Financial performance, year by year

Fiscal 2023–2025 · USD
$-13.73M$-12.26M$-10.80M$-9.33M$-7.87M202320242025Last 12 moLast 12 months

The full income statement, balance sheet and cash flow for each of these years — every figure traceable to its filing — is on the Financials tab with a free account.

Ownership

Who owns Cadrenal Therapeutics, Inc. — and what changed

Funds as of 2026Q2 · superinvestors as of 2026-06-30

8
funds hold it
0 of 35
superinvestors hold it
$0.26M
held by funds, at market
1.9%
of shares held by funds

Largest fund holders · Cadrenal Therapeutics, Inc.’s weight in each

VANGUARD TOTAL STOCK MARKET INDEX FUND
VTI · VANGUARD INDEX FUNDS
0.00%of fund net assets
Fidelity Extended Market Index Fund
FSMAX · Fidelity Concord Street Trust
—of fund net assets
VANGUARD EXTENDED MARKET INDEX FUND
VXF · VANGUARD INDEX FUNDS
0.00%of fund net assets
Fidelity Series Total Market Index Fund
FCFMX · Fidelity Concord Street Trust
—of fund net assets
Fidelity Nasdaq Composite Index Fund
FNCMX · Fidelity Concord Street Trust
—of fund net assets

Fund ownership is a floor, not a census — pensions, insurers and people holding shares directly are not visible here.

Fund ownership counts N-PORT filers only, so it is a floor rather than a census — pensions, insurers and direct holders are not visible here, and the remainder is not “held by individuals”.

Could not be determined for this company: bond issues.

Every fund and institutional holder, quarter by quarter, is on the Ownership tab with a free account.

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