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Companies / Health Care / Cardiff Oncology, Inc.
CRDF

Cardiff Oncology, Inc.

Health CareBiological Products
Ticker CRDFSAN DIEGO, CAFiscal year ends DecemberBook value per share $0.39Diluted shares 68.4M

Cardiff Oncology, Inc. (Nasdaq: CRDF) is a clinical-stage biotechnology company developing cancer therapies based on PLK1 inhibition. Its lead drug candidate, onvansertib, is an oral, selective PLK1 inhibitor being studied in combination with standard-of-care treatments, particularly for RAS-mutated metastatic… From the company’s description.

Over the twelve months to Jun 30, 2026, Cardiff Oncology, Inc. reported revenue of $0.51M, down 6.8% from a year earlier, and a net loss of $40.05M. Operations used $40.85M in cash. In fiscal 2025, it reported revenue of $0.59M, down 13.2% from fiscal 2024, and a net loss of $45.85M.

Fiscal year 2025 · ends 12-31Changes are against fiscal 2024The amber dot is the latest twelve months, to 2026-06-30
Sales & profitability
$0.59MFY2025
−13.2% year over year
Last 12 mo $0.51M
-8256.32%FY2025
−1133.2 percentage points
Last 12 mo -8320.08%
$-45.85MFY2025
−0.9% year over year
Last 12 mo $-40.05M
-101.02%FY2025
−46.3 percentage points
Last 12 mo -150.95%
Cash & financing
$-37.92MFY2025
−0.6% year over year
Last 12 mo $-40.85M
$-37.97MFY2025
−0.5% year over year
Last 12 mo $-40.92M
—
66.8MFY2025
+40.3% year over year
Last 12 mo 68.4M

Margins and return on equity change in ; everything else in percent. Fewer shares and less debt are shown plainly, not as bad news — it depends what you make of buybacks. Dotted labels explain each measure. is shown separately from the annual figures.

What Cardiff Oncology, Inc. does

In the company’s own words

Cardiff Oncology, Inc. (Nasdaq: CRDF) is a clinical-stage biotechnology company developing cancer therapies based on PLK1 inhibition. Its lead drug candidate, onvansertib, is an oral, selective PLK1 inhibitor being studied in combination with standard-of-care treatments, particularly for RAS-mutated metastatic colorectal cancer; investigator-led trials also evaluate it in pancreatic cancer, small cell lung cancer, triple-negative breast cancer and chronic myelomonocytic leukemia. The company uses tumor genomics and biomarker testing to guide patient selection and assess treatment response, and relies on third-party manufacturers and distributors for onvansertib used in clinical and nonclinical programs. Cardiff operates as one business segment. In its colorectal cancer program, a Phase 2 trial evaluates onvansertib with chemotherapy and bevacizumab, while Pfizer Ignite supports clinical activities; Cardiff retains economic ownership and control of the drug candidate. Its laboratory is in San Diego, and its principal operations, assets and decision-making functions are in the United States. Its website is www.cardiffoncology.com.

Company details
Sector
Health Care
Industry (SIC)
Biological Products
Headquarters
SAN DIEGO, CA
Fiscal year end
December
CIK
1213037
SIC
2836

Financial performance, year by year

Fiscal 2012–2025 · USD
$-50.50M$-36.54M$-22.58M$-8.62M$5.34M20122013201420152016201720182019202020212022202320242025Last 12 moLast 12 monthsLast 12 months

The full income statement, balance sheet and cash flow for each of these years — every figure traceable to its filing — is on the Financials tab with a free account.

Ownership

Who owns Cardiff Oncology, Inc. — and what changed

Funds as of 2026Q2 · superinvestors as of 2026-06-30

53
funds hold it
0 of 35
superinvestors hold it
$8.74M
held by funds, at market
7.4%
of shares held by funds

Largest fund holders · Cardiff Oncology, Inc.’s weight in each

VANGUARD TOTAL STOCK MARKET INDEX FUND
VTI · VANGUARD INDEX FUNDS
0.00%of fund net assets
Fidelity Small Cap Index Fund
FSSNX · Fidelity Salem Street Trust
—of fund net assets
VANGUARD EXTENDED MARKET INDEX FUND
VXF · VANGUARD INDEX FUNDS
0.00%of fund net assets
Franklin Biotechnology Discovery Fund
FBDIX · Franklin Strategic Series
—of fund net assets
Fidelity Extended Market Index Fund
FSMAX · Fidelity Concord Street Trust
—of fund net assets

Fund ownership is a floor, not a census — pensions, insurers and people holding shares directly are not visible here.

Fund ownership counts N-PORT filers only, so it is a floor rather than a census — pensions, insurers and direct holders are not visible here, and the remainder is not “held by individuals”.

Every fund and institutional holder, quarter by quarter, is on the Ownership tab with a free account.

Connected research

Put this business in context.

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