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Companies / Health Care / Caris Life Sciences, Inc.
CAI

Caris Life Sciences, Inc.

Health CareHealth Services
Ticker CAIIRVING, TXFiscal year ends DecemberBook value per share $2.17Diluted shares 294.2M

Caris Life Sciences, Inc. (Nasdaq: CAI) develops molecular profiling and data-driven solutions for precision medicine, primarily in oncology, serving physicians, patients, academic researchers, and biopharmaceutical companies. Its offerings include tissue- and blood-based sequencing and analysis to support cancer… From the company’s description.

In fiscal 2025, Caris Life Sciences, Inc. reported revenue of $812.03M and a net loss of $68.09M. Its operating margin was 5.6%, and operations generated $83.16M in cash. Over the twelve months to Sep 30, 2026, revenue was $1.05B.

Fiscal year 2025 · ends 12-31The amber dot is the latest twelve months, to 2026-09-30
Sales & profitability
$812.03MFY2025
Last 12 mo $1.05B
5.56%FY2025
Last 12 mo 13.35%
$-68.09MFY2025
Last 12 mo $96.06M
-11.79%FY2025
Last 12 mo 15.02%
Cash & financing
$83.16MFY2025
Last 12 mo $83.89M
$66.89MFY2025
Last 12 mo $28.91M
0.66FY2025
Last 12 mo 0.61
167.2MFY2025
Last 12 mo 294.2M

Dotted labels explain each measure. is shown separately from the annual figures.

What Caris Life Sciences, Inc. does

In the company’s own words

Caris Life Sciences, Inc. (Nasdaq: CAI) develops molecular profiling and data-driven solutions for precision medicine, primarily in oncology, serving physicians, patients, academic researchers, and biopharmaceutical companies. Its offerings include tissue- and blood-based sequencing and analysis to support cancer diagnosis and therapy selection, with additional solutions in development for early detection, minimal residual disease tracking, and treatment monitoring. Caris also uses its molecular data, laboratory capabilities, and artificial intelligence tools to identify drug targets and develop therapeutics, both with biopharma partners and through its own pipeline. Its business includes the Molecular Intelligence portfolio, Caris Discovery, strategic data capabilities, and supporting laboratory, research, and commercial infrastructure. Key products and tools include MI Profile, Caris Assure, MI Cancer Seek, GPSai, FOLFIRSTai, and the developing Caris Detect assay. As of December 31, 2025, the company had sequenced more than 1 million cases and served over 6,000 U.S. ordering physicians.

Company details
Sector
Health Care
Industry (SIC)
Health Services
Headquarters
IRVING, TX
Fiscal year end
December
CIK
2019410
SIC
8071

Financial performance, year by year

Fiscal 2025–2025 · USD
$-179.71M$155.16M$490.02M$824.89M$1.16B2025Last 12 moLast 12 monthsLast 12 months

The full income statement, balance sheet and cash flow for each of these years — every figure traceable to its filing — is on the Financials tab with a free account.

Ownership

Who owns Caris Life Sciences, Inc. — and what changed

Funds as of 2026Q2 · superinvestors as of 2026-06-30

222
funds hold it
1 of 35
superinvestors hold it
$1.05B
held by funds, at market
20.6%
of shares held by funds

Superinvestors in Caris Life Sciences, Inc. · what they did last quarter

Stanley DruckenmillerUNCHANGED
Duquesne Family Office
0.8%of 13F portfolio

Share of each manager’s reported 13F portfolio. Change is in shares held, since the previous quarter.

Largest fund holders · Caris Life Sciences, Inc.’s weight in each

VANGUARD TOTAL STOCK MARKET INDEX FUND
VTI · VANGUARD INDEX FUNDS
0.00%of fund net assets
Select Health Care Portfolio
FSPHX · Fidelity Select Portfolios
—of fund net assets
JPMorgan Mid Cap Growth Fund
HLGEX · JPMorgan Trust II
0.45%of fund net assets
0.03%of fund net assets
VANGUARD SMALL-CAP INDEX FUND
VB · VANGUARD INDEX FUNDS
0.03%of fund net assets

Fund ownership is a floor, not a census — pensions, insurers and people holding shares directly are not visible here.

Fund ownership counts N-PORT filers only, so it is a floor rather than a census — pensions, insurers and direct holders are not visible here, and the remainder is not “held by individuals”.

Fund ownership is a subset of institutional 13F ownership — the two describe overlapping populations and must not be added together.

Every fund and institutional holder, quarter by quarter, is on the Ownership tab with a free account.

Connected research

Put this business in context.

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  • “How do Caris Life Sciences, Inc. and its peers compare on margins and cash generation over ten years?”
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