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Companies / Health Care / Celldex Therapeutics, Inc.
CLDX

Celldex Therapeutics, Inc.

Health CareChemicals
Ticker CLDXHAMPTON, NJFiscal year ends DecemberBook value per share $8.73Diluted shares 74.4M

Celldex Therapeutics, Inc. (Nasdaq: CLDX) is a biopharmaceutical company developing therapeutic antibodies for severe inflammatory, allergic, autoimmune and other diseases, with a focus on conditions driven by mast cells. Its lead candidate, barzolvolimab, is a monoclonal antibody that targets the KIT receptor and is… From the company’s description.

Over the twelve months to Sep 30, 2026, Celldex Therapeutics, Inc. reported revenue of $0.16M, down 93.9% from a year earlier, and a net loss of $309.06M. Operations used $251.97M in cash. In fiscal 2025, it reported revenue of $1.54M, down 78.0% from fiscal 2024, and a net loss of $258.76M.

Fiscal year 2025 · ends 12-31Changes are against fiscal 2024The amber dot is the latest twelve months, to 2026-09-30
Sales & profitability
$1.54MFY2025
−78.0% year over year
Last 12 mo $0.16M
-18599.81%FY2025
−15820.9 percentage points
Last 12 mo -211684.81%
$-258.76MFY2025
−63.9% year over year
Last 12 mo $-309.06M
-49.08%FY2025
−28 percentage points
Last 12 mo -47.59%
Cash & financing
$-210.94MFY2025
−33.7% year over year
Last 12 mo $-251.97M
$-213.66MFY2025
−33.8% year over year
Last 12 mo $-259.74M
—
66.4MFY2025
+3.1% year over year
Last 12 mo 74.4M

Margins and return on equity change in ; everything else in percent. Fewer shares and less debt are shown plainly, not as bad news — it depends what you make of buybacks. Dotted labels explain each measure. is shown separately from the annual figures.

What Celldex Therapeutics, Inc. does

In the company’s own words

Celldex Therapeutics, Inc. (Nasdaq: CLDX) is a biopharmaceutical company developing therapeutic antibodies for severe inflammatory, allergic, autoimmune and other diseases, with a focus on conditions driven by mast cells. Its lead candidate, barzolvolimab, is a monoclonal antibody that targets the KIT receptor and is being studied in chronic spontaneous and inducible urticaria, prurigo nodularis and atopic dermatitis. Celldex is also developing CDX-622, a bispecific antibody that targets TSLP and SCF, and uses its bispecific antibody platform to pursue additional candidates for inflammatory diseases. The company’s research and development programs serve patients with significant unmet treatment needs; it has no commercial product sales. Celldex reports its business as one operating segment. For the fiscal year ended December 31, 2025, it reported $[missing] million in revenue. Its website is https://www.celldex.com.

Company details
Sector
Health Care
Industry (SIC)
Chemicals
Headquarters
HAMPTON, NJ
Fiscal year end
December
CIK
744218
SIC
2835

Financial performance, year by year

Fiscal 2011–2025 · USD
$-341.24M$-244.70M$-148.16M$-51.62M$44.92M201120122013201420152016201720182019202020212022202320242025Last 12 moLast 12 monthsLast 12 months

The full income statement, balance sheet and cash flow for each of these years — every figure traceable to its filing — is on the Financials tab with a free account.

Ownership

Who owns Celldex Therapeutics, Inc. — and what changed

Funds as of 2026Q2 · superinvestors as of 2026-06-30

245
funds hold it
0 of 35
superinvestors hold it
$1.05B
held by funds, at market
38.4%
of shares held by funds

Largest fund holders · Celldex Therapeutics, Inc.’s weight in each

VANGUARD HEALTH CARE FUND
VGHCX · VANGUARD SPECIALIZED FUNDS
—of fund net assets
VANGUARD TOTAL STOCK MARKET INDEX FUND
VTI · VANGUARD INDEX FUNDS
0.00%of fund net assets
iShares Russell 2000 ETF
IWM · iShares Trust
0.09%of fund net assets
0.70%of fund net assets
T. Rowe Price New Horizons Fund, Inc.
PRNHX · T. ROWE PRICE NEW HORIZONS FUND, INC.
0.32%of fund net assets

Fund ownership is a floor, not a census — pensions, insurers and people holding shares directly are not visible here.

Fund ownership counts N-PORT filers only, so it is a floor rather than a census — pensions, insurers and direct holders are not visible here, and the remainder is not “held by individuals”.

Every fund and institutional holder, quarter by quarter, is on the Ownership tab with a free account.

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