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Companies / Healthcare / CervoMed Inc.
CRVO

CervoMed Inc.

HealthcarePharmaceutical Preparations
Ticker CRVOBOSTON, MAFiscal year ends DecemberBook value per share $7.08Diluted shares 3.2M

CervoMed Inc. (Nasdaq: CRVO) is a clinical-stage biotechnology company developing innovative treatments for age-related brain disorders. The company's lead drug candidate, neflamapimod, is an investigational orally administered small-molecule that selectively inhibits p38α, an enzyme believed to drive… From the company’s description.

Fiscal year 2025 · ends 12-31Changes are against fiscal 2024The amber dot is the latest twelve months, to 2026-06-30
Sales & profitability
$4.01M
−58.9% year over year
Last 12 mo $0.33M
-706.22%
−519 percentage points
Last 12 mo -9406.96%
$-26.97M
−65.5% year over year
Last 12 mo $-30.35M
-147.98%
−106.4 percentage points
Last 12 mo -132.18%
Cash & financing
$-23.45M
−41.9% year over year
Last 12 mo $-27.98M
$-23.45M
−41.9% year over year
Last 12 mo $-27.98M
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Margins and return on equity change in ; everything else in percent. Fewer shares and less debt are shown plainly, not as bad news — it depends what you make of buybacks. Dotted labels explain each measure. is shown separately from the annual figures.

What CervoMed Inc. does

In the company’s own words

CervoMed Inc. (Nasdaq: CRVO) is a clinical-stage biotechnology company developing innovative treatments for age-related brain disorders. The company's lead drug candidate, neflamapimod, is an investigational orally administered small-molecule that selectively inhibits p38α, an enzyme believed to drive neuroinflammation and synaptic dysfunction in neurodegenerative diseases. By targeting neuroinflammation, neflamapimod has the potential to reverse synaptic dysfunction, improve neuron health, and slow or prevent disease progression.

CervoMed's primary focus is advancing neflamapimod for dementia with Lewy bodies, the second most common progressive dementia affecting millions worldwide, for which no approved treatments currently exist in the United States or European Union. The company's differentiated approach targets DLB patients without Alzheimer's disease co-pathology, a population representing approximately fifty percent of all DLB cases. This strategy enables demonstration of clinical effects in shorter trial durations with fewer patients compared to traditional neurodegenerative disease development programs. Beyond DLB, neflamapimod is in clinical development for non-fluent variant primary progressive aphasia, recovery after stroke, and amyotrophic lateral sclerosis.

The company was formed through a merger completed on August 16, 2023, between Diffusion Pharmaceuticals Inc. and EIP Pharma Inc., with EIP surviving as a wholly-owned subsidiary. CervoMed's clinical pipeline includes the RewinD-LB Phase 2b trial, which demonstrated statistically significant improvements on clinical endpoints and biomarkers of neurodegeneration. In November 2025, the company announced alignment with the FDA on key aspects of its planned Phase 3 clinical trial in DLB, which is anticipated to initiate in the second half of 2026. The company received a $21.3 million grant from the National Institute on Aging to support the RewinD-LB Trial. CervoMed is classified as a smaller reporting company and non-accelerated filer. The company's website is www.cervomedpharma.com.

Company details
Sector
Healthcare
Industry
Pharmaceutical Preparations
Headquarters
BOSTON, MA
Fiscal year end
December
CIK
1053691
SIC
2834

Financial performance, year by year

Fiscal 2013–2025 · USD
$-34.36M$-22.33M$-10.31M$1.72M$13.75M2013201420152016201720182019202020212022202320242025Last 12 moLast 12 monthsLast 12 months

The full income statement, balance sheet and cash flow for each of these years — every figure traceable to its filing — is on the Financials tab with a free account.

Ownership

Who owns CervoMed Inc. — and what changed

Funds as of 2026Q2 · superinvestors as of 2026-06-30

9
funds hold it
0 of 35
superinvestors hold it
$1.25M
held by funds, at market
2.7%
of shares held by funds

Largest fund holders · CervoMed Inc.’s weight in each

VANGUARD TOTAL STOCK MARKET INDEX FUND
VTI · VANGUARD INDEX FUNDS
0.00%of fund net assets
VANGUARD EXTENDED MARKET INDEX FUND
VXF · VANGUARD INDEX FUNDS
0.00%of fund net assets
Fidelity Extended Market Index Fund
FSMAX · Fidelity Concord Street Trust
0.00%of fund net assets
iShares Micro-Cap ETF
IWC · iShares Trust
0.00%of fund net assets
Fidelity Total Market Index Fund
FSKAX · Fidelity Concord Street Trust
0.00%of fund net assets

Fund ownership is a floor, not a census — pensions, insurers and people holding shares directly are not visible here.

Fund ownership counts N-PORT filers only, so it is a floor rather than a census — pensions, insurers and direct holders are not visible here, and the remainder is not “held by individuals”.

Every fund and institutional holder, quarter by quarter, is on the Ownership tab with a free account.

Connected research

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