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Companies / Health Care / Compass Therapeutics, Inc.
CMPX

Compass Therapeutics, Inc.

Health CareBiological Products
Ticker CMPXBOSTON, MAFiscal year ends DecemberBook value per share $2.64Diluted shares 62.9M

Compass Therapeutics, Inc. (Nasdaq: CMPX) is a clinical-stage biopharmaceutical company developing antibody-based therapeutics, primarily for cancer. Its research focuses on angiogenesis, the immune system and tumor growth, with candidates designed to affect tumor blood vessels and immune responses. The company has… From the company’s description.

In fiscal 2025, Compass Therapeutics, Inc. reported a net loss of $66.49M. Operations used $49.14M in cash.

Fiscal year 2025 · ends 12-31Changes are against fiscal 2024The amber dot is the latest twelve months, to 2026-06-30
Sales & profitability
$0.00MFY2025
−100.0% year over year
0.00%FY2025
$-66.49MFY2025
−34.7% year over year
Last 12 mo $-73.45M
-33.79%FY2025
+5.6 percentage points
Last 12 mo -44.23%
Cash & financing
$-49.14MFY2025
−9.6% year over year
Last 12 mo $-56.11M
$-49.17MFY2025
−9.5% year over year
Last 12 mo $-56.38M
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Margins and return on equity change in ; everything else in percent. Fewer shares and less debt are shown plainly, not as bad news — it depends what you make of buybacks. Dotted labels explain each measure. is shown separately from the annual figures.

What Compass Therapeutics, Inc. does

In the company’s own words

Compass Therapeutics, Inc. (Nasdaq: CMPX) is a clinical-stage biopharmaceutical company developing antibody-based therapeutics, primarily for cancer. Its research focuses on angiogenesis, the immune system and tumor growth, with candidates designed to affect tumor blood vessels and immune responses. The company has four clinical-stage candidates: tovecimig, a DLL4/VEGF-A bispecific antibody being studied in solid tumors; CTX-471, an antibody that activates the CD137 immune receptor; CTX-8371, a bispecific antibody targeting PD-1 and PD-L1; and CTX-10726, a bispecific antibody targeting PD-1 and VEGF-A. The candidates are intended for development as standalone therapies and in combinations with other drugs or pipeline antibodies. Compass also develops additional antibody candidates through its research and discovery platform. It holds exclusive global rights outside South Korea to tovecimig, originally licensed from South Korea-based ABL Bio, and its wholly owned subsidiaries include Trigr Therapeutics. Compass Therapeutics reports a pipeline rather than operating revenue segments; it has no products approved for commercial sale. Its website is https://compasstherapeutics.com.

Company details
Sector
Health Care
Industry (SIC)
Biological Products
Headquarters
BOSTON, MA
Fiscal year end
December
CIK
1738021
SIC
2836

Financial performance, year by year

Fiscal 2018–2025 · USD
$-90.48M$-65.57M$-40.67M$-15.76M$9.15M201820192019202020212022202320242025Last 12 moLast 12 months

The full income statement, balance sheet and cash flow for each of these years — every figure traceable to its filing — is on the Financials tab with a free account.

Ownership

Who owns Compass Therapeutics, Inc. — and what changed

Funds as of 2026Q2 · superinvestors as of 2026-06-30

144
funds hold it
0 of 35
superinvestors hold it
$69.78M
held by funds, at market
17.9%
of shares held by funds

Largest fund holders · Compass Therapeutics, Inc.’s weight in each

0.14%of fund net assets
VANGUARD TOTAL STOCK MARKET INDEX FUND
VTI · VANGUARD INDEX FUNDS
0.00%of fund net assets
iShares Russell 2000 ETF
IWM · iShares Trust
0.01%of fund net assets
VANGUARD EXTENDED MARKET INDEX FUND
VXF · VANGUARD INDEX FUNDS
0.00%of fund net assets
iShares Russell 2000 Value ETF
IWN · iShares Trust
0.02%of fund net assets

Fund ownership is a floor, not a census — pensions, insurers and people holding shares directly are not visible here.

Fund ownership counts N-PORT filers only, so it is a floor rather than a census — pensions, insurers and direct holders are not visible here, and the remainder is not “held by individuals”.

Could not be determined for this company: bond issues.

Every fund and institutional holder, quarter by quarter, is on the Ownership tab with a free account.

Connected research

Put this business in context.

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  • “How do Compass Therapeutics, Inc. and its peers compare on margins and cash generation over ten years?”
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