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Companies / Healthcare / Corbus Pharmaceuticals Holdings, Inc.
CRBP

Corbus Pharmaceuticals Holdings, Inc.

HealthcarePharmaceutical Preparations
Ticker CRBPNORWOOD, MAFiscal year ends DecemberBook value per share $5.36Diluted shares 19.1M

Corbus Pharmaceuticals Holdings, Inc. (NASDAQ: CRBP) is a clinical-stage biopharmaceutical company focused on developing innovative therapies in oncology and obesity. The company is committed to bringing scientific approaches to well-understood biological pathways to help patients defeat serious illness. From the company’s description.

Fiscal year 2025 · ends 12-31Changes are against fiscal 2024The amber dot is the latest twelve months, to 2026-06-30
Sales & profitability
—
0.00%
$-78.54M
−95.3% year over year
Last 12 mo $-101.90M
-53.24%
−25 percentage points
Last 12 mo -99.67%
Cash & financing
$-64.49M
−54.3% year over year
Last 12 mo $-86.67M
$-64.50M
−54.3% year over year
Last 12 mo $-86.67M
—
Was 0.00× a year earlier
13.3M
+22.0% year over year
Last 12 mo 19.1M

Margins and return on equity change in ; everything else in percent. Fewer shares and less debt are shown plainly, not as bad news — it depends what you make of buybacks. Dotted labels explain each measure. is shown separately from the annual figures.

What Corbus Pharmaceuticals Holdings, Inc. does

In the company’s own words

Corbus Pharmaceuticals Holdings, Inc. (NASDAQ: CRBP) is a clinical-stage biopharmaceutical company focused on developing innovative therapies in oncology and obesity. The company is committed to bringing scientific approaches to well-understood biological pathways to help patients defeat serious illness.

The company's primary pipeline consists of two lead candidates. CRB-701 is a next-generation antibody drug conjugate targeting Nectin-4 expression on cancer cells, designed to deliver a cytotoxic payload of monomethyl auristatin E. Licensed from CSPC Megalith Biopharmaceutical Co. Ltd. in February 2023, CRB-701 is being evaluated in a Phase 1/2 clinical trial in the United States and Europe for advanced solid tumors including head and neck squamous cell carcinoma, cervical cancer, and metastatic urothelial cancer. The drug has received fast track designation from the FDA for relapsed or refractory metastatic cervical cancer and recurrent or metastatic head and neck squamous cell carcinoma. CRB-913 is a highly peripherally restricted oral small molecule CB1 receptor inverse agonist for obesity treatment, representing a distinct mechanism of action from GLP-1 therapies. The company completed a Phase 1a study in December 2025 and initiated a Phase 1b dose-range finding study in December 2025.

Corbus also maintains CRB-601, an anti-αvβ8 integrin monoclonal antibody for solid tumors, though the company has deprioritized this program. The company incurred research and development expenses of $70.1 million in 2025 compared to $32.2 million in 2024, reflecting increased investment in clinical development activities.

The company does not operate manufacturing facilities and relies on third-party contract manufacturing organizations and licensing partners for drug supply. Corbus maintains intellectual property protection through licensed patents and proprietary technology platforms, with patent protections for its candidates extending through 2042 to 2046 depending on the program.

More information about Corbus Pharmaceuticals is available at www.corbuspharma.com.

Company details
Sector
Healthcare
Industry
Pharmaceutical Preparations
Headquarters
NORWOOD, MA
Fiscal year end
December
CIK
1595097
SIC
2834

Financial performance, year by year

Fiscal 2014–2025 · USD
$-126.01M$-81.79M$-37.56M$6.66M$50.88M201420152016201720182019202020212022202320242025Last 12 moLast 12 months

The full income statement, balance sheet and cash flow for each of these years — every figure traceable to its filing — is on the Financials tab with a free account.

Ownership

Who owns Corbus Pharmaceuticals Holdings, Inc. — and what changed

Funds as of 2026Q2 · superinvestors as of 2026-06-30

70
funds hold it
0 of 35
superinvestors hold it
$30.00M
held by funds, at market
16.6%
of shares held by funds

Largest fund holders · Corbus Pharmaceuticals Holdings, Inc.’s weight in each

0.54%of fund net assets
0.74%of fund net assets
VANGUARD TOTAL STOCK MARKET INDEX FUND
VTI · VANGUARD INDEX FUNDS
0.00%of fund net assets
iShares Russell 2000 ETF
IWM · iShares Trust
0.00%of fund net assets
VANGUARD EXTENDED MARKET INDEX FUND
VXF · VANGUARD INDEX FUNDS
0.00%of fund net assets

Fund ownership is a floor, not a census — pensions, insurers and people holding shares directly are not visible here.

Fund ownership counts N-PORT filers only, so it is a floor rather than a census — pensions, insurers and direct holders are not visible here, and the remainder is not “held by individuals”.

Every fund and institutional holder, quarter by quarter, is on the Ownership tab with a free account.

Connected research

Put this business in context.

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