10x Insights
Loading account…
Companies / Health Care / Curis, Inc.
CRIS

Curis, Inc.

Health CareBiological Products
Ticker CRISLEXINGTON, MAFiscal year ends DecemberBook value per share $3.02Diluted shares 1.6M

Curis, Inc. (Nasdaq: CRIS) is a biotechnology company developing emavusertib, an orally available small-molecule inhibitor of IRAK4 and FLT3, for hematologic cancers. The drug candidate is being evaluated with ibrutinib in a Phase 1/2 study for relapsed or refractory primary central nervous system lymphoma and with… From the company’s description.

Over the twelve months to Jun 30, 2026, Curis, Inc. reported revenue of $4.31M, down 62.2% from a year earlier, and a net loss of $21.15M. Its operating margin was −203.2%, and operations used $30.59M in cash. In fiscal 2025, it reported revenue of $9.44M, down 13.4% from fiscal 2024, and a net loss of $7.58M.

Fiscal year 2025 · ends 12-31Changes are against fiscal 2024The amber dot is the latest twelve months, to 2026-06-30
Sales & profitability
$9.44MFY2025
−13.4% year over year
Last 12 mo $4.31M
-60.50%FY2025
+347.8 percentage points
Last 12 mo -203.15%
$-7.58MFY2025
+82.5% year over year
Last 12 mo $-21.15M
-138.81%FY2025
−862.2 percentage points
Last 12 mo -450.54%
Cash & financing
$-27.20MFY2025
+31.2% year over year
Last 12 mo $-30.59M
$-27.20MFY2025
+31.2% year over year
Last 12 mo $-30.59M
0.00FY2025
Was -1.26× a year earlier
13.2MFY2025
+108.7% year over year
Last 12 mo 1.6M

Margins and return on equity change in ; everything else in percent. Fewer shares and less debt are shown plainly, not as bad news — it depends what you make of buybacks. Dotted labels explain each measure. is shown separately from the annual figures.

What Curis, Inc. does

In the company’s own words

Curis, Inc. (Nasdaq: CRIS) is a biotechnology company developing emavusertib, an orally available small-molecule inhibitor of IRAK4 and FLT3, for hematologic cancers. The drug candidate is being evaluated with ibrutinib in a Phase 1/2 study for relapsed or refractory primary central nervous system lymphoma and with zanubrutinib in a Phase 2 study for chronic lymphocytic leukemia; its acute myeloid leukemia studies are substantially complete. Curis licenses emavusertib from Aurigene Discovery Technologies under a collaboration that also covers other oncology programs. The company has no reportable business segments described in the provided business overview and is focused on drug research and development rather than marketed products. In November 2025, Curis sold its Erivedge-related assets and rights under its Genentech license, ending its entitlement to revenue from that product. Curis had $5.1 million in cash and cash equivalents at December 31, 2025. Its website is www.curis.com.

Company details
Sector
Health Care
Industry (SIC)
Biological Products
Headquarters
LEXINGTON, MA
Fiscal year end
December
CIK
1108205
SIC
2836

Financial performance, year by year

Fiscal 2011–2025 · USD
$-68.15M$-44.93M$-21.72M$1.50M$24.71M201120122013201420152016201720182019202020212022202320242025Last 12 moLast 12 monthsLast 12 months

The full income statement, balance sheet and cash flow for each of these years — every figure traceable to its filing — is on the Financials tab with a free account.

Ownership

Who owns Curis, Inc. — and what changed

Funds as of 2026Q2 · superinvestors as of 2026-06-30

7
funds hold it
0 of 35
superinvestors hold it
$0.25M
held by funds, at market
22.0%
of shares held by funds

Largest fund holders · Curis, Inc.’s weight in each

VANGUARD TOTAL STOCK MARKET INDEX FUND
VTI · VANGUARD INDEX FUNDS
0.00%of fund net assets
Fidelity Extended Market Index Fund
FSMAX · Fidelity Concord Street Trust
—of fund net assets
VANGUARD EXTENDED MARKET INDEX FUND
VXF · VANGUARD INDEX FUNDS
0.00%of fund net assets
Fidelity Series Total Market Index Fund
FCFMX · Fidelity Concord Street Trust
—of fund net assets
Fidelity Total Market Index Fund
FSKAX · Fidelity Concord Street Trust
—of fund net assets

Fund ownership is a floor, not a census — pensions, insurers and people holding shares directly are not visible here.

Fund ownership counts N-PORT filers only, so it is a floor rather than a census — pensions, insurers and direct holders are not visible here, and the remainder is not “held by individuals”.

Every fund and institutional holder, quarter by quarter, is on the Ownership tab with a free account.

Connected research

Put this business in context.

Compare this company with peers, find it in your funds and follow its financial history with your connected AI:

  • “How do Curis, Inc. and its peers compare on margins and cash generation over ten years?”
  • “Where did five years of Curis, Inc.'s earnings go — cash, debt, buybacks, reinvestment?”
  • “What changed in Curis, Inc.'s last four quarterly filings that the numbers alone won't show?”
See how it works →All research tools with a subscription. Use your own AI account.