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Companies / Health Care / Design Therapeutics, Inc.
DSGN

Design Therapeutics, Inc.

Health CarePharmaceutical Preparations
Ticker DSGNCARLSBAD, CAFiscal year ends DecemberBook value per share $3.24Diluted shares 62.3M

Design Therapeutics, Inc. (Nasdaq: DSGN) is a clinical-stage biopharmaceutical company developing GeneTAC® small-molecule therapeutics for inherited diseases caused by nucleotide repeat expansions. Its platform is designed to target expanded genetic sequences and modulate gene expression to address either deficient… From the company’s description.

In fiscal 2025, Design Therapeutics, Inc. reported a net loss of $69.79M. Operations used $54.36M in cash.

Fiscal year 2025 · ends 12-31Changes are against fiscal 2024The amber dot is the latest twelve months, to 2026-09-30
Sales & profitability
—
0.00%FY2025
$-69.79MFY2025
−40.7% year over year
Last 12 mo $-74.09M
-32.84%FY2025
−12.4 percentage points
Last 12 mo -36.64%
Cash & financing
$-54.36MFY2025
−26.1% year over year
Last 12 mo $-59.30M
$-54.55MFY2025
−25.6% year over year
Last 12 mo $-59.37M
—
57.3MFY2025
+1.3% year over year
Last 12 mo 62.3M

Margins and return on equity change in ; everything else in percent. Fewer shares and less debt are shown plainly, not as bad news — it depends what you make of buybacks. Dotted labels explain each measure. is shown separately from the annual figures.

What Design Therapeutics, Inc. does

In the company’s own words

Design Therapeutics, Inc. (Nasdaq: DSGN) is a clinical-stage biopharmaceutical company developing GeneTAC® small-molecule therapeutics for inherited diseases caused by nucleotide repeat expansions. Its platform is designed to target expanded genetic sequences and modulate gene expression to address either deficient proteins or toxic gene products. The company’s programs include DT-216P2 for Friedreich ataxia and DT-168 for Fuchs endothelial corneal dystrophy, both in clinical development; DT-818 for myotonic dystrophy type 1, cleared to begin clinical development; and preclinical candidates for Huntington’s disease and other conditions. GeneTAC® is the company’s principal technology and product platform, and its development candidates are intended to address disease mechanisms at the genetic level. The company focuses on patients with inherited repeat-expansion diseases and does not report separate business segments. Its website is www.designtx.com.

Company details
Sector
Health Care
Industry (SIC)
Pharmaceutical Preparations
Headquarters
CARLSBAD, CA
Fiscal year end
December
CIK
1807120
SIC
2834

Financial performance, year by year

Fiscal 2021–2025 · USD
$-77.94M$-66.38M$-54.81M$-43.24M$-31.68M20212022202320242025Last 12 moLast 12 months

The full income statement, balance sheet and cash flow for each of these years — every figure traceable to its filing — is on the Financials tab with a free account.

Ownership

Who owns Design Therapeutics, Inc. — and what changed

Funds as of 2026Q2 · superinvestors as of 2026-06-30

148
funds hold it
0 of 35
superinvestors hold it
$92.87M
held by funds, at market
10.9%
of shares held by funds

Largest fund holders · Design Therapeutics, Inc.’s weight in each

VANGUARD TOTAL STOCK MARKET INDEX FUND
VTI · VANGUARD INDEX FUNDS
0.00%of fund net assets
iShares Russell 2000 ETF
IWM · iShares Trust
0.01%of fund net assets
Select Biotechnology Portfolio
FBIOX · Fidelity Select Portfolios
—of fund net assets
VANGUARD EXTENDED MARKET INDEX FUND
VXF · VANGUARD INDEX FUNDS
0.01%of fund net assets
0.03%of fund net assets

Fund ownership is a floor, not a census — pensions, insurers and people holding shares directly are not visible here.

Fund ownership counts N-PORT filers only, so it is a floor rather than a census — pensions, insurers and direct holders are not visible here, and the remainder is not “held by individuals”.

Could not be determined for this company: bond issues.

Every fund and institutional holder, quarter by quarter, is on the Ownership tab with a free account.

Connected research

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