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Companies / Health Care / Entrada Therapeutics, Inc.
TRDA

Entrada Therapeutics, Inc.

Health CarePharmaceutical Preparations
Ticker TRDABOSTON, MAFiscal year ends DecemberBook value per share $4.71Diluted shares 42.1M

Entrada Therapeutics, Inc. (Nasdaq: TRDA) is a clinical-stage biopharmaceutical company developing genetic medicines for diseases involving targets inside cells. Its proprietary Endosomal Escape Vehicle (EEV) platform is designed to deliver therapeutic molecules into cells; its lead programs pair EEV peptides with… From the company’s description.

Over the twelve months to Sep 30, 2026, Entrada Therapeutics, Inc. reported revenue of $3.98M, down 93.5% from a year earlier, and a net loss of $161.39M. Operations used $136.32M in cash. In fiscal 2025, it reported revenue of $25.42M, down 87.9% from fiscal 2024, and a net loss of $143.75M.

Fiscal year 2025 · ends 12-31Changes are against fiscal 2024The amber dot is the latest twelve months, to 2026-09-30
Sales & profitability
$25.42MFY2025
−87.9% year over year
Last 12 mo $3.98M
-621.13%FY2025
−643.4 percentage points
Last 12 mo -4303.82%
$-143.75MFY2025
−319.0% year over year
Last 12 mo $-161.39M
-46.96%FY2025
−62.3 percentage points
Last 12 mo -81.37%
Cash & financing
$-128.51MFY2025
−209.2% year over year
Last 12 mo $-136.32M
$-129.55MFY2025
−189.7% year over year
Last 12 mo $-136.33M
—
41.4MFY2025
+6.1% year over year
Last 12 mo 42.1M

Margins and return on equity change in ; everything else in percent. Fewer shares and less debt are shown plainly, not as bad news — it depends what you make of buybacks. Dotted labels explain each measure. is shown separately from the annual figures.

What Entrada Therapeutics, Inc. does

In the company’s own words

Entrada Therapeutics, Inc. (Nasdaq: TRDA) is a clinical-stage biopharmaceutical company developing genetic medicines for diseases involving targets inside cells. Its proprietary Endosomal Escape Vehicle (EEV) platform is designed to deliver therapeutic molecules into cells; its lead programs pair EEV peptides with oligonucleotides to address neuromuscular diseases, especially Duchenne muscular dystrophy (DMD). Clinical-stage DMD candidates ENTR-601-44, ENTR-601-45 and ENTR-601-50 target distinct mutations through exon skipping, while ENTR-601-51 is advancing toward clinical studies. Entrada also supports Vertex Pharmaceuticals’ development of VX-670, an EEV-based candidate for myotonic dystrophy type 1, under a global collaboration in which Vertex holds an exclusive license and leads development, manufacturing and commercialization. In ocular disease, the company is developing oligonucleotide-based programs, including ENTR-801 for Usher syndrome type 2A. Its pipeline spans clinical and preclinical programs, with no reportable business segments described. Its website is www.entradatx.com.

Company details
Sector
Health Care
Industry (SIC)
Pharmaceutical Preparations
Headquarters
BOSTON, MA
Fiscal year end
December
CIK
1689375
SIC
2834

Financial performance, year by year

Fiscal 2021–2025 · USD
$-198.60M$-86.95M$24.70M$136.35M$248.00M20212022202320242025Last 12 moLast 12 monthsLast 12 months

The full income statement, balance sheet and cash flow for each of these years — every figure traceable to its filing — is on the Financials tab with a free account.

Ownership

Who owns Entrada Therapeutics, Inc. — and what changed

Funds as of 2026Q2 · superinvestors as of 2026-06-30

139
funds hold it
0 of 35
superinvestors hold it
$45.20M
held by funds, at market
14.0%
of shares held by funds

Largest fund holders · Entrada Therapeutics, Inc.’s weight in each

VANGUARD TOTAL STOCK MARKET INDEX FUND
VTI · VANGUARD INDEX FUNDS
0.00%of fund net assets
iShares Russell 2000 ETF
IWM · iShares Trust
0.01%of fund net assets
Fidelity Small Cap Index Fund
FSSNX · Fidelity Salem Street Trust
—of fund net assets
T. Rowe Price Health Sciences Fund, Inc.
PRHSX · T. ROWE PRICE HEALTH SCIENCES FUND, INC.
0.02%of fund net assets
VANGUARD EXTENDED MARKET INDEX FUND
VXF · VANGUARD INDEX FUNDS
0.00%of fund net assets

Fund ownership is a floor, not a census — pensions, insurers and people holding shares directly are not visible here.

Fund ownership counts N-PORT filers only, so it is a floor rather than a census — pensions, insurers and direct holders are not visible here, and the remainder is not “held by individuals”.

Could not be determined for this company: bond issues.

Every fund and institutional holder, quarter by quarter, is on the Ownership tab with a free account.

Connected research

Put this business in context.

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