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Companies / Health Care / Equillium, Inc.
EQ

Equillium, Inc.

Health CarePharmaceutical Preparations
Ticker EQLA JOLLA, CAFiscal year ends DecemberBook value per share $0.54Diluted shares 104.1M

Equillium (Nasdaq: EQ) is a biotechnology company developing therapies for severe autoimmune and inflammatory disorders. Its preclinical pipeline includes EQ504, an aryl hydrocarbon receptor modulator initially being developed for ulcerative colitis and other gastrointestinal diseases, with potential applications in… From the company’s description.

In fiscal 2025, Equillium, Inc. reported a net loss of $22.40M. Operations used $22.75M in cash.

Fiscal year 2025 · ends 12-31Changes are against fiscal 2024The amber dot is the latest twelve months, to 2026-06-30
Sales & profitability
—
0.00%FY2025
$-22.40MFY2025
−177.6% year over year
Last 12 mo $-18.01M
-78.32%FY2025
−36 percentage points
Last 12 mo -32.15%
Cash & financing
$-22.75MFY2025
−19.6% year over year
Last 12 mo $-19.97M
$-22.79MFY2025
−19.3% year over year
Last 12 mo $-20.09M
—
57.3MFY2025
+62.1% year over year
Last 12 mo 104.1M

Margins and return on equity change in ; everything else in percent. Fewer shares and less debt are shown plainly, not as bad news — it depends what you make of buybacks. Dotted labels explain each measure. is shown separately from the annual figures.

What Equillium, Inc. does

In the company’s own words

Equillium (Nasdaq: EQ) is a biotechnology company developing therapies for severe autoimmune and inflammatory disorders. Its preclinical pipeline includes EQ504, an aryl hydrocarbon receptor modulator initially being developed for ulcerative colitis and other gastrointestinal diseases, with potential applications in inflammatory lung diseases, and EQ302, an orally delivered, selective inhibitor of IL-15 and IL-21 being evaluated for gastrointestinal conditions such as celiac disease. The company acquired EQ504 through its 2024 acquisition of Ariagen and EQ302 through its 2022 acquisition of Bioniz. Equillium has no commercial organization or manufacturing facilities; it relies on third-party contract manufacturers for product supplies and has not yet established sales or distribution capabilities. Its website is https://www.equilliumbio.com/.

Company details
Sector
Health Care
Industry (SIC)
Pharmaceutical Preparations
Headquarters
LA JOLLA, CA
Fiscal year end
December
CIK
1746466
SIC
2834

Financial performance, year by year

Fiscal 2018–2025 · USD
$-72.78M$-41.72M$-10.67M$20.39M$51.45M20182019202020212022202320242025Last 12 moLast 12 months

The full income statement, balance sheet and cash flow for each of these years — every figure traceable to its filing — is on the Financials tab with a free account.

Ownership

Who owns Equillium, Inc. — and what changed

Funds as of 2026Q2 · superinvestors as of 2026-06-30

15
funds hold it
0 of 35
superinvestors hold it
$18.91M
held by funds, at market
9.4%
of shares held by funds

Largest fund holders · Equillium, Inc.’s weight in each

1.69%of fund net assets
VANGUARD TOTAL STOCK MARKET INDEX FUND
VTI · VANGUARD INDEX FUNDS
0.00%of fund net assets
VANGUARD EXTENDED MARKET INDEX FUND
VXF · VANGUARD INDEX FUNDS
0.00%of fund net assets
Fidelity Extended Market Index Fund
FSMAX · Fidelity Concord Street Trust
—of fund net assets
iShares Micro-Cap ETF
IWC · iShares Trust
0.03%of fund net assets

Fund ownership is a floor, not a census — pensions, insurers and people holding shares directly are not visible here.

Fund ownership counts N-PORT filers only, so it is a floor rather than a census — pensions, insurers and direct holders are not visible here, and the remainder is not “held by individuals”.

Every fund and institutional holder, quarter by quarter, is on the Ownership tab with a free account.

Connected research

Put this business in context.

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  • “How do Equillium, Inc. and its peers compare on margins and cash generation over ten years?”
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