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Companies / Healthcare / EXICURE, INC.
XCUR

EXICURE, INC.

HealthcarePharmaceutical Preparations
Ticker XCURCHICAGO, ILFiscal year ends DecemberBook value per share $0.15Diluted shares 6.4M

Exicure, Inc. (Nasdaq: XCUR) operates as a biotechnology company exploring strategic alternatives to maximize stockholder value. The company maintains its website at www.exicuretx.com and is headquartered in California with eight full-time employees as of December 31, 2025. From the company’s description.

Fiscal year 2025 · ends 12-31Changes are against fiscal 2024The amber dot is the latest twelve months, to 2026-06-30
Sales & profitability
$0.00M
−100.0% year over year
Last 12 mo $0.00M
0.00%
$-4.95M
+49.0% year over year
Last 12 mo $-8.28M
-125.98%
−67.1 percentage points
Last 12 mo -847.90%
Cash & financing
$-8.55M
−194.0% year over year
Last 12 mo $-6.70M
$-8.56M
−194.0% year over year
Last 12 mo $-7.02M
—
6.3M
+208.2% year over year
Last 12 mo 6.4M

Margins and return on equity change in ; everything else in percent. Fewer shares and less debt are shown plainly, not as bad news — it depends what you make of buybacks. Dotted labels explain each measure. is shown separately from the annual figures.

What EXICURE, INC. does

In the company’s own words

Exicure, Inc. (Nasdaq: XCUR) operates as a biotechnology company exploring strategic alternatives to maximize stockholder value. The company maintains its website at www.exicuretx.com and is headquartered in California with eight full-time employees as of December 31, 2025.

Historically, Exicure focused on developing nucleic acid therapies targeting ribonucleic acid against validated targets using its proprietary spherical nucleic acid (SNA) technology platform. The company significantly restructured in September 2022, suspending preclinical activities and halting all research and development while exploring strategic alternatives. In September 2024, Exicure sold its historical biotechnology intellectual property and other assets, including SNA-related technology and clinical assets, to Flashpoint Therapeutics, Inc., recognizing $1.5 million in other income from this transaction.

The company's current strategic focus involves exploring growth through acquisitions and transactions with potential partners seeking to join an existing publicly-traded organization. In January 2025, Exicure acquired GPCR Therapeutics USA Inc., a subsidiary of Korean corporation GPCR Therapeutics Inc., and entered into a License and Collaboration Agreement to develop and commercialize GPCR's technologies. GPCR USA completed a Phase 2 clinical trial in January 2026 focused on blood cancer patients, with ongoing clinical trials involving GPC-100, a small molecule antagonist, combined with propranolol for stem cell mobilization in Multiple Myeloma patients.

In March 2025, Exicure formed KC Creation Co., Ltd., a wholly-owned South Korean subsidiary to explore collaboration opportunities and growth strategies, though management decided to sell this subsidiary in November 2025. The company also established a significant relationship with HiTron, which beneficially owns approximately 25 percent of outstanding common stock as of March 17, 2026, following common stock purchase agreements totaling $10 million in aggregate consideration.

Exicure currently generates no product revenue and relies on strategic partnerships and potential licensing arrangements for value realization. The company faces substantial doubt regarding its ability to continue as a going concern and requires significant additional capital to fund operations and pursue strategic alternatives. As of December 31, 2025, the company maintained approximately $3.7 million in cash and cash equivalents.

Company details
Sector
Healthcare
Industry
Pharmaceutical Preparations
Headquarters
CHICAGO, IL
Fiscal year end
December
CIK
1698530
SIC
2834

Financial performance, year by year

Fiscal 2017–2025 · USD
$-73.39M$-45.52M$-17.64M$10.24M$38.12M201720182019202020212022202320242025Last 12 moLast 12 monthsLast 12 months

The full income statement, balance sheet and cash flow for each of these years — every figure traceable to its filing — is on the Financials tab with a free account.

Ownership

Who owns EXICURE, INC. — and what changed

Funds as of 2026Q2 · superinvestors as of 2026-06-30

7
funds hold it
0 of 35
superinvestors hold it
$0.19M
held by funds, at market
1.1%
of shares held by funds

Largest fund holders · EXICURE, INC.’s weight in each

Fidelity Extended Market Index Fund
FSMAX · Fidelity Concord Street Trust
0.00%of fund net assets
VANGUARD EXTENDED MARKET INDEX FUND
VXF · VANGUARD INDEX FUNDS
0.00%of fund net assets
VANGUARD TOTAL STOCK MARKET INDEX FUND
VTI · VANGUARD INDEX FUNDS
0.00%of fund net assets
Fidelity Total Market Index Fund
FSKAX · Fidelity Concord Street Trust
0.00%of fund net assets
Fidelity Series Total Market Index Fund
FCFMX · Fidelity Concord Street Trust
0.00%of fund net assets

Fund ownership is a floor, not a census — pensions, insurers and people holding shares directly are not visible here.

Fund ownership counts N-PORT filers only, so it is a floor rather than a census — pensions, insurers and direct holders are not visible here, and the remainder is not “held by individuals”.

Every fund and institutional holder, quarter by quarter, is on the Ownership tab with a free account.

Connected research

Put this business in context.

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