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Companies / Health Care / Foghorn Therapeutics Inc.
FHTX

Foghorn Therapeutics Inc.

Health CarePharmaceutical Preparations
Ticker FHTXCAMBRIDGE, MAFiscal year ends DecemberBook value per share $-1.16Diluted shares 70.1M

Foghorn Therapeutics Inc. (Nasdaq: FHTX) is a clinical-stage biotechnology company developing medicines that target the chromatin regulatory system to correct abnormal gene expression, primarily in genetically defined cancers. Its small-molecule approaches include enzyme inhibitors, protein degraders and… From the company’s description.

Over the twelve months to Jun 30, 2026, Foghorn Therapeutics Inc. reported revenue of $36.74M, up 52.0% from a year earlier, and a net loss of $64.58M. Its operating margin was −198.0%, and operations used $84.24M in cash. In fiscal 2025, it reported revenue of $30.91M, up 36.8% from fiscal 2024, and a net loss of $74.28M.

Fiscal year 2025 · ends 12-31Changes are against fiscal 2024The amber dot is the latest twelve months, to 2026-06-30
Sales & profitability
$30.91MFY2025
+36.8% year over year
Last 12 mo $36.74M
-279.49%FY2025
+174.8 percentage points
Last 12 mo -198.04%
$-74.28MFY2025
+14.2% year over year
Last 12 mo $-64.58M
68.46%FY2025
−116.5 percentage points
Last 12 mo 79.69%
Cash & financing
$-86.10MFY2025
+14.2% year over year
Last 12 mo $-84.24M
$-86.15MFY2025
+15.0% year over year
Last 12 mo $-84.29M
—
63.0MFY2025
+14.7% year over year
Last 12 mo 70.1M

Margins and return on equity change in ; everything else in percent. Fewer shares and less debt are shown plainly, not as bad news — it depends what you make of buybacks. Dotted labels explain each measure. is shown separately from the annual figures.

What Foghorn Therapeutics Inc. does

In the company’s own words

Foghorn Therapeutics Inc. (Nasdaq: FHTX) is a clinical-stage biotechnology company developing medicines that target the chromatin regulatory system to correct abnormal gene expression, primarily in genetically defined cancers. Its small-molecule approaches include enzyme inhibitors, protein degraders and transcription-factor disruptors, with research also exploring applications beyond oncology. Foghorn’s Gene Traffic Control platform supports target identification and validation, drug discovery and biomarker development. Its pipeline includes programs targeting SMARCA2, CBP, EP300 and ARID1B; the lead candidate, oral SMARCA2 inhibitor FHD-909, is in a Phase 1 trial for advanced solid tumors with SMARCA4 mutations, with non-small cell lung cancer as the primary patient population. Through its collaboration with Eli Lilly, the companies are advancing oncology programs, including the SMARCA2 program, under a U.S. co-development and co-commercialization agreement. Foghorn has more than seven programs and had 106 employees as of December 31, 2025. Its website is https://www.foghorntx.com.

Company details
Sector
Health Care
Industry (SIC)
Pharmaceutical Preparations
Headquarters
CAMBRIDGE, MA
Fiscal year end
December
CIK
1822462
SIC
2834

Financial performance, year by year

Fiscal 2020–2025 · USD
$-123.44M$-79.76M$-36.07M$7.61M$51.30M202020212022202320242025Last 12 moLast 12 monthsLast 12 months

The full income statement, balance sheet and cash flow for each of these years — every figure traceable to its filing — is on the Financials tab with a free account.

Ownership

Who owns Foghorn Therapeutics Inc. — and what changed

Funds as of 2026Q2 · superinvestors as of 2026-06-30

98
funds hold it
0 of 35
superinvestors hold it
$35.55M
held by funds, at market
13.0%
of shares held by funds

Largest fund holders · Foghorn Therapeutics Inc.’s weight in each

Fidelity Growth Company Fund
FDGRX · Fidelity Mt. Vernon Street Trust
—of fund net assets
VANGUARD TOTAL STOCK MARKET INDEX FUND
VTI · VANGUARD INDEX FUNDS
0.00%of fund net assets
iShares Russell 2000 ETF
IWM · iShares Trust
0.01%of fund net assets
Fidelity Growth Company K6 Fund
FGKFX · Fidelity Mt. Vernon Street Trust
—of fund net assets
VANGUARD EXTENDED MARKET INDEX FUND
VXF · VANGUARD INDEX FUNDS
0.00%of fund net assets

Fund ownership is a floor, not a census — pensions, insurers and people holding shares directly are not visible here.

Fund ownership counts N-PORT filers only, so it is a floor rather than a census — pensions, insurers and direct holders are not visible here, and the remainder is not “held by individuals”.

Could not be determined for this company: bond issues.

Every fund and institutional holder, quarter by quarter, is on the Ownership tab with a free account.

Connected research

Put this business in context.

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