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Companies / Healthcare / GALECTIN THERAPEUTICS INC
GALT

GALECTIN THERAPEUTICS INC

HealthcarePharmaceutical Preparations
Ticker GALTNORCROSS, GAFiscal year ends DecemberBook value per share $-2.11Diluted shares 65.8M

Galectin Therapeutics Inc. (GALT) is a clinical-stage biopharmaceutical company focused on developing novel therapies targeting galectin proteins, which are key mediators of inflammation, fibrosis, and immune dysfunction. The company's website is www.galectintherapeutics.com. From the company’s description.

Fiscal year 2025 · ends 12-31Changes are against fiscal 2024The amber dot is the latest twelve months, to 2026-06-30
Sales & profitability
—
0.00%
$-30.84M
+34.5% year over year
Last 12 mo $-27.84M
24.11%
−20.8 percentage points
Last 12 mo 20.09%
Cash & financing
$-23.88M
+42.8% year over year
Last 12 mo $-15.89M
$-23.88M
+42.8% year over year
Last 12 mo $-15.89M
-1.05
Was -1.01× a year earlier
Last 12 mo -0.99
63.9M
+2.6% year over year
Last 12 mo 65.8M

Margins and return on equity change in ; everything else in percent. Fewer shares and less debt are shown plainly, not as bad news — it depends what you make of buybacks. Dotted labels explain each measure. is shown separately from the annual figures.

What GALECTIN THERAPEUTICS INC does

In the company’s own words

Galectin Therapeutics Inc. (GALT) is a clinical-stage biopharmaceutical company focused on developing novel therapies targeting galectin proteins, which are key mediators of inflammation, fibrosis, and immune dysfunction. The company's website is www.galectintherapeutics.com.

The company's lead product candidate is belapectin (GR-MD-02), a proprietary complex carbohydrate derived from naturally occurring plant products that binds and inhibits galectin-3. Belapectin is currently in clinical development for metabolic dysfunction-associated steatohepatitis (MASH) with cirrhosis and certain cancer indications. The company has completed two Phase 1 clinical studies, a Phase 2 trial in MASH patients with advanced fibrosis (NASH-FX), and a Phase 2b trial in MASH patients with compensated cirrhosis and portal hypertension (NASH-CX). Most recently, the company completed enrollment in the NAVIGATE Phase 2b/3 trial evaluating belapectin for prevention of esophageal varices in MASH cirrhosis patients, with top-line results presented in December 2024.

Beyond its lead indication, Galectin is pursuing belapectin in cancer immunotherapy, particularly for head and neck squamous cell carcinoma in combination with checkpoint inhibitors. The company filed an IND with the FDA in 2022 for this indication and received a Study May Proceed letter. Additionally, through its majority-owned joint venture subsidiary Galectin Sciences LLC, the company is developing small molecule galectin-3 inhibitors designed for oral administration to expand treatment potential beyond belapectin.

Galectin was founded in July 2000 as Pro-Pharmaceuticals Inc. and changed its name to Galectin Therapeutics Inc. in May 2011. The company relocated its headquarters to the Atlanta area in 2012 while maintaining laboratory operations in the Boston region. As a development-stage company, Galectin outsources research, manufacturing, and clinical trial operations to third-party providers. During 2025, the company expended approximately 14.3 million dollars on research and development activities. The company is classified as a smaller reporting company and is not a well-known seasoned issuer.

Company details
Sector
Healthcare
Industry
Pharmaceutical Preparations
Headquarters
NORCROSS, GA
Fiscal year end
December
CIK
1133416
SIC
2834

Financial performance, year by year

Fiscal 2013–2025 · USD
$-50.54M$-40.06M$-29.57M$-19.08M$-8.59M2013201420152016201720182019202020212022202320242025Last 12 moLast 12 months

The full income statement, balance sheet and cash flow for each of these years — every figure traceable to its filing — is on the Financials tab with a free account.

Ownership

Who owns GALECTIN THERAPEUTICS INC — and what changed

Funds as of 2026Q2 · superinvestors as of 2026-06-30

57
funds hold it
0 of 35
superinvestors hold it
$20.96M
held by funds, at market
4.8%
of shares held by funds

Largest fund holders · GALECTIN THERAPEUTICS INC’s weight in each

VANGUARD TOTAL STOCK MARKET INDEX FUND
VTI · VANGUARD INDEX FUNDS
0.00%of fund net assets
iShares Russell 2000 ETF
IWM · iShares Trust
0.01%of fund net assets
VANGUARD EXTENDED MARKET INDEX FUND
VXF · VANGUARD INDEX FUNDS
0.00%of fund net assets
0.01%of fund net assets
iShares Micro-Cap ETF
IWC · iShares Trust
0.05%of fund net assets

Fund ownership is a floor, not a census — pensions, insurers and people holding shares directly are not visible here.

Fund ownership counts N-PORT filers only, so it is a floor rather than a census — pensions, insurers and direct holders are not visible here, and the remainder is not “held by individuals”.

Every fund and institutional holder, quarter by quarter, is on the Ownership tab with a free account.

Connected research

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