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Companies / Health Care / Heron Therapeutics, Inc.
HRTX

Heron Therapeutics, Inc.

Health CarePharmaceutical Preparations
Ticker HRTXSAN DIEGO, CAFiscal year ends DecemberBook value per share $0.04Diluted shares 190.0M

Heron Therapeutics, Inc. (Nasdaq: HRTX) is a commercial-stage biotechnology company that develops and sells medicines for acute-care and oncology patients. Its acute-care portfolio includes ZYNRELEF, an extended-release combination of bupivacaine and meloxicam for postsurgical pain, and APONVIE, an intravenous… From the company’s description.

Over the twelve months to Jun 30, 2026, Heron Therapeutics, Inc. reported revenue of $151.18M, up 1.0% from a year earlier, and a net loss of $34.05M. Its operating margin was −7.2%, and operations used $11.61M in cash. In fiscal 2025, it reported revenue of $154.90M, up 7.4% from fiscal 2024, and a net loss of $20.20M.

Fiscal year 2025 · ends 12-31Changes are against fiscal 2024The amber dot is the latest twelve months, to 2026-06-30
Sales & profitability
$154.90MFY2025
+7.4% year over year
Last 12 mo $151.18M
-1.64%FY2025
+6.4 percentage points
Last 12 mo -7.19%
$-20.20MFY2025
−48.7% year over year
Last 12 mo $-34.05M
-140.90%FY2025
−181.3 percentage points
Last 12 mo -492.89%
Cash & financing
$-27.59MFY2025
−22.5% year over year
Last 12 mo $-11.61M
$-27.91MFY2025
−15.2% year over year
Last 12 mo $-12.13M
9.81FY2025
Was -5.19× a year earlier
Last 12 mo 20.65
166.7MFY2025
+9.4% year over year
Last 12 mo 190.0M

Margins and return on equity change in ; everything else in percent. Fewer shares and less debt are shown plainly, not as bad news — it depends what you make of buybacks. Dotted labels explain each measure. is shown separately from the annual figures.

What Heron Therapeutics, Inc. does

In the company’s own words

Heron Therapeutics, Inc. (Nasdaq: HRTX) is a commercial-stage biotechnology company that develops and sells medicines for acute-care and oncology patients. Its acute-care portfolio includes ZYNRELEF, an extended-release combination of bupivacaine and meloxicam for postsurgical pain, and APONVIE, an intravenous aprepitant product for preventing postoperative nausea and vomiting. Its oncology portfolio includes CINVANTI, an intravenous aprepitant product used with other antiemetics to prevent chemotherapy-induced nausea and vomiting, and SUSTOL, an extended-release granisetron injection for preventing nausea and vomiting associated with chemotherapy. The company’s proprietary Biochronomer technology is designed to release medicines over days to weeks after a single administration. Heron sells its products in the United States through specialty distributors and full-line wholesalers to healthcare providers and hospitals. Its focused sales force serves surgeons, oncologists, nurses and pharmacists, while its commercial team works with healthcare accounts and payors. The U.S. sales and marketing team had 78 employees as of December 31, 2025.

Company details
Sector
Health Care
Industry (SIC)
Pharmaceutical Preparations
Headquarters
SAN DIEGO, CA
Fiscal year end
December
CIK
818033
SIC
2834

Financial performance, year by year

Fiscal 2011–2025 · USD
$-265.50M$-150.84M$-36.19M$78.47M$193.12M201120122013201420152016201720182019202020212022202320242025Last 12 moLast 12 monthsLast 12 months

The full income statement, balance sheet and cash flow for each of these years — every figure traceable to its filing — is on the Financials tab with a free account.

Ownership

Who owns Heron Therapeutics, Inc. — and what changed

Funds as of 2026Q2 · superinvestors as of 2026-06-30

101
funds hold it
0 of 35
superinvestors hold it
$14.14M
held by funds, at market
12.3%
of shares held by funds

Largest fund holders · Heron Therapeutics, Inc.’s weight in each

VANGUARD TOTAL STOCK MARKET INDEX FUND
VTI · VANGUARD INDEX FUNDS
0.00%of fund net assets
Fidelity Small Cap Index Fund
FSSNX · Fidelity Salem Street Trust
—of fund net assets
iShares Russell 2000 ETF
IWM · iShares Trust
0.00%of fund net assets
VANGUARD EXTENDED MARKET INDEX FUND
VXF · VANGUARD INDEX FUNDS
0.00%of fund net assets
Schwab U.S. Small-Cap ETF
SCHA · SCHWAB STRATEGIC TRUST
—of fund net assets

Fund ownership is a floor, not a census — pensions, insurers and people holding shares directly are not visible here.

Fund ownership counts N-PORT filers only, so it is a floor rather than a census — pensions, insurers and direct holders are not visible here, and the remainder is not “held by individuals”.

Every fund and institutional holder, quarter by quarter, is on the Ownership tab with a free account.

Connected research

Put this business in context.

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