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Companies / Healthcare / HYPERION DEFI, INC.
HYPD

HYPERION DEFI, INC.

HealthcarePharmaceutical Preparations
Ticker HYPDDALLAS, TXFiscal year ends DecemberBook value per share $6.85Diluted shares 14.9M

Hyperion DeFi, Inc. (Nasdaq: HYPE) operates as the first U.S. publicly listed company building a strategic treasury of Hyperliquid's native token, HYPE, while continuing development of digital ophthalmic technology products. The company maintains its website at www.hyperiondefi.com. From the company’s description.

Fiscal year 2025 · ends 12-31Changes are against fiscal 2024The amber dot is the latest twelve months, to 2026-06-30
Sales & profitability
$0.81M
+1318.8% year over year
Last 12 mo $1.40M
-5743.53%
+79261 percentage points
Last 12 mo 314.33%
$-45.31M
+9.0% year over year
Last 12 mo $6.65M
-110.36%
−490.8 percentage points
Last 12 mo 6.53%
Cash & financing
$-14.77M
+51.0% year over year
Last 12 mo $-13.97M
$-86.72M
−186.4% year over year
Last 12 mo $-13.97M
0.19
Was -0.76× a year earlier
Last 12 mo 0.08
5.0M
+500.3% year over year
Last 12 mo 14.9M

Margins and return on equity change in ; everything else in percent. Fewer shares and less debt are shown plainly, not as bad news — it depends what you make of buybacks. Dotted labels explain each measure. is shown separately from the annual figures.

What HYPERION DEFI, INC. does

In the company’s own words

Hyperion DeFi, Inc. (Nasdaq: HYPE) operates as the first U.S. publicly listed company building a strategic treasury of Hyperliquid's native token, HYPE, while continuing development of digital ophthalmic technology products. The company maintains its website at www.hyperiondefi.com.

The company's primary business focus centers on accumulating and deploying HYPE tokens as part of a broader decentralized finance monetization roadmap. Hyperliquid is a Layer 1 blockchain engineered for high-frequency transparent finance, hosting fully on-chain perpetual futures and spot order books with transaction settlement occurring within 70 millisecond block times and supporting up to 200,000 transactions per second. As of February 2026, Hyperliquid generates approximately one billion dollars in annual fees and ranks eleventh by market capitalization among digital assets excluding stablecoins.

Hyperion DeFi's digital assets strategy extends beyond simple token accumulation. The company operates a co-branded validator called Kinetiq x Hyperion on the Hyperliquid network in partnership with Kinetiq Research and Pier Two, participating directly in network consensus and earning staking rewards. The company stakes a majority of its HYPE tokens and engages in liquid staking through protocols like Kinetiq, receiving liquid staking tokens including HiHYPE, kHYPE, and kmHYPE that maintain liquidity while earning rewards. The company has established HYPE Asset Use Service agreements with third-party protocols including Credo Cayman, Felix, and Native Markets, generating fee-based income from transaction volumes and protocol earnings.

For digital asset custody, Hyperion DeFi holds HYPE in self-custodied cold wallet addresses using infrastructure from Porto by Anchorage Digital Bank, a federally chartered cryptocurrency bank, and hardware wallet providers including Ledger. Anchorage Digital provides institutional-grade security and insurance coverage for custodial accounts.

Beyond its cryptocurrency treasury strategy, Hyperion DeFi continues developing the Optejet User Filled Device, a proprietary ophthalmic liquid delivery system designed for topical eye medications. The company had nine full-time employees as of December 31, 2025, and engages various consultants and contractors to support operations.

Company details
Sector
Healthcare
Industry
Pharmaceutical Preparations
Headquarters
DALLAS, TX
Fiscal year end
December
CIK
1682639
SIC
2834

Financial performance, year by year

Fiscal 2017–2025 · USD
$-56.20M$-37.05M$-17.91M$1.24M$20.38M201720182019202020212022202320242025Last 12 moLast 12 monthsLast 12 months

The full income statement, balance sheet and cash flow for each of these years — every figure traceable to its filing — is on the Financials tab with a free account.

Ownership

Who owns HYPERION DEFI, INC. — and what changed

Funds as of 2026Q2 · superinvestors as of 2026-06-30

12
funds hold it
0 of 35
superinvestors hold it
$3.22M
held by funds, at market
6.3%
of shares held by funds

Largest fund holders · HYPERION DEFI, INC.’s weight in each

Putnam Small Cap Value Fund
PSLAX · Putnam Investment Funds
0.34%of fund net assets
VANGUARD TOTAL STOCK MARKET INDEX FUND
VTI · VANGUARD INDEX FUNDS
0.00%of fund net assets
VANGUARD EXTENDED MARKET INDEX FUND
VXF · VANGUARD INDEX FUNDS
0.00%of fund net assets
Putnam VT Small Cap Value Fund
Putnam Variable Trust
0.28%of fund net assets
Fidelity Extended Market Index Fund
FSMAX · Fidelity Concord Street Trust
0.00%of fund net assets

Fund ownership is a floor, not a census — pensions, insurers and people holding shares directly are not visible here.

Fund ownership counts N-PORT filers only, so it is a floor rather than a census — pensions, insurers and direct holders are not visible here, and the remainder is not “held by individuals”.

Every fund and institutional holder, quarter by quarter, is on the Ownership tab with a free account.

Connected research

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