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Companies / Health Care / INOVIO Pharmaceuticals, Inc.
INO

INOVIO Pharmaceuticals, Inc.

Health CarePharmaceutical Preparations
Ticker INOPLYMOUTH MEETING, PAFiscal year ends DecemberBook value per share $0.06Diluted shares 75.4M

INOVIO Pharmaceuticals, Inc. (Nasdaq: INO) is a clinical-stage biotechnology company developing DNA medicines for HPV-associated diseases, cancer, and infectious diseases. Its platform combines engineered DNA plasmids, which direct cells to produce disease-targeting proteins, with proprietary CELLECTRA electroporation… From the company’s description.

Over the twelve months to Jun 30, 2026, INOVIO Pharmaceuticals, Inc. reported a net loss of $67.43M. Operations used $80.58M in cash. In fiscal 2025, it reported revenue of $0.07M, down 70.0% from fiscal 2024, and a net loss of $84.95M.

Fiscal year 2025 · ends 12-31Changes are against fiscal 2024The amber dot is the latest twelve months, to 2026-06-30
Sales & profitability
$0.07MFY2025
−70.0% year over year
Last 12 mo $0.00M
-132871.32%FY2025
−81254.4 percentage points
$-84.95MFY2025
+20.8% year over year
Last 12 mo $-67.43M
-352.53%FY2025
−195.9 percentage points
Last 12 mo -1542.71%
Cash & financing
$-88.63MFY2025
+14.8% year over year
Last 12 mo $-80.58M
$-88.92MFY2025
+15.0% year over year
Last 12 mo $-80.78M
—
Was 0.00× a year earlier
46.9MFY2025
+72.6% year over year
Last 12 mo 75.4M

Margins and return on equity change in ; everything else in percent. Fewer shares and less debt are shown plainly, not as bad news — it depends what you make of buybacks. Dotted labels explain each measure. is shown separately from the annual figures.

What INOVIO Pharmaceuticals, Inc. does

In the company’s own words

INOVIO Pharmaceuticals, Inc. (Nasdaq: INO) is a clinical-stage biotechnology company developing DNA medicines for HPV-associated diseases, cancer, and infectious diseases. Its platform combines engineered DNA plasmids, which direct cells to produce disease-targeting proteins, with proprietary CELLECTRA electroporation devices designed to deliver the plasmids into cells. The lead candidate, INO-3107, is under FDA review as a potential treatment for adults with recurrent respiratory papillomatosis, a disease that often requires repeated surgery. Other programs address HPV-related cancers and precancers, glioblastoma and other cancers, Ebola, HIV, and COVID-19; earlier-stage platforms include DNA-encoded antibodies and proteins. INOVIO has no reportable business segments described in its operations and earns revenue from licensing, milestones, and collaborative research and development rather than product sales. All product candidates remain in research and development. For fiscal 2025, the company reports no product-sale revenue. Its CELLECTRA and SynCon technologies support its development programs, and partners include pharmaceutical companies, government agencies, and academic institutions. Its website is https://www.inovio.com/.

Company details
Sector
Health Care
Industry (SIC)
Pharmaceutical Preparations
Headquarters
PLYMOUTH MEETING, PA
Fiscal year end
December
CIK
1055726
SIC
2834

Financial performance, year by year

Fiscal 2011–2025 · USD
$-338.25M$-234.48M$-130.72M$-26.96M$76.81M201120122013201420152016201720182019202020212022202320242025Last 12 moLast 12 monthsLast 12 months

The full income statement, balance sheet and cash flow for each of these years — every figure traceable to its filing — is on the Financials tab with a free account.

Ownership

Who owns INOVIO Pharmaceuticals, Inc. — and what changed

Funds as of 2026Q2 · superinvestors as of 2026-06-30

20
funds hold it
0 of 35
superinvestors hold it
$14.90M
held by funds, at market
12.8%
of shares held by funds

Largest fund holders · INOVIO Pharmaceuticals, Inc.’s weight in each

Fidelity Small Cap Growth Fund
FCPGX · Fidelity Securities Fund
—of fund net assets
Fidelity Small Cap Growth K6 Fund
FOCSX · Fidelity Securities Fund
—of fund net assets
VANGUARD TOTAL STOCK MARKET INDEX FUND
VTI · VANGUARD INDEX FUNDS
0.00%of fund net assets
VANGUARD EXTENDED MARKET INDEX FUND
VXF · VANGUARD INDEX FUNDS
0.00%of fund net assets
Fidelity Extended Market Index Fund
FSMAX · Fidelity Concord Street Trust
—of fund net assets

Fund ownership is a floor, not a census — pensions, insurers and people holding shares directly are not visible here.

Fund ownership counts N-PORT filers only, so it is a floor rather than a census — pensions, insurers and direct holders are not visible here, and the remainder is not “held by individuals”.

Every fund and institutional holder, quarter by quarter, is on the Ownership tab with a free account.

Connected research

Put this business in context.

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  • “How do INOVIO Pharmaceuticals, Inc. and its peers compare on margins and cash generation over ten years?”
  • “Where did five years of INOVIO Pharmaceuticals, Inc.'s earnings go — cash, debt, buybacks, reinvestment?”
  • “What changed in INOVIO Pharmaceuticals, Inc.'s last four quarterly filings that the numbers alone won't show?”
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