10x Insights
Loading account…
Companies / Health Care / Ironwood Pharmaceuticals, Inc.
IRWD

Ironwood Pharmaceuticals, Inc.

Health CarePharmaceutical Preparations
Ticker IRWDBOSTON, MAFiscal year ends DecemberBook value per share $-0.58Diluted shares 167.5M

Ironwood Pharmaceuticals, Inc. (Nasdaq: IRWD) is a biotechnology company developing and commercializing therapies for gastrointestinal and rare diseases. Its commercial product, LINZESS (linaclotide), treats irritable bowel syndrome with constipation and chronic idiopathic constipation in adults, as well as functional… From the company’s description.

Over the twelve months to Sep 30, 2026, Ironwood Pharmaceuticals, Inc. reported revenue of $400.30M, up 18.1% from a year earlier, and net income of $149.63M. Its operating margin was 62.9%, and operations generated $205.37M in cash. In fiscal 2025, it reported revenue of $296.15M, down 15.7% from fiscal 2024, and net income of $24.02M.

Fiscal year 2025 · ends 12-31Changes are against fiscal 2024The amber dot is the latest twelve months, to 2026-09-30
Sales & profitability
$296.15MFY2025
−15.7% year over year
Last 12 mo $400.30M
33.26%FY2025
+6.8 percentage points
Last 12 mo 62.91%
$24.02MFY2025
+2629.2% year over year
Last 12 mo $149.63M
-11.83%FY2025
−11.5 percentage points
Last 12 mo -153.75%
Cash & financing
$127.04MFY2025
+22.7% year over year
Last 12 mo $205.37M
$127.01MFY2025
+22.8% year over year
Last 12 mo $205.37M
-2.23FY2025
Was -1.94× a year earlier
Last 12 mo -3.34
163.0MFY2025
+1.8% year over year
Last 12 mo 167.5M

Margins and return on equity change in ; everything else in percent. Fewer shares and less debt are shown plainly, not as bad news — it depends what you make of buybacks. Dotted labels explain each measure. is shown separately from the annual figures.

What Ironwood Pharmaceuticals, Inc. does

In the company’s own words

Ironwood Pharmaceuticals, Inc. (Nasdaq: IRWD) is a biotechnology company developing and commercializing therapies for gastrointestinal and rare diseases. Its commercial product, LINZESS (linaclotide), treats irritable bowel syndrome with constipation and chronic idiopathic constipation in adults, as well as functional constipation in children; it is marketed in some countries as CONSTELLA. Ironwood shares U.S. commercialization of LINZESS with AbbVie, while AbbVie, Astellas and AstraZeneca commercialize linaclotide in other territories. The company is advancing apraglutide, a once-weekly peptide drug candidate for short bowel syndrome with intestinal failure in patients dependent on parenteral support, and plans a confirmatory Phase III trial. Ironwood’s revenue is derived substantially from linaclotide partnerships, particularly its U.S. collaboration with AbbVie. In 2025, it recognized $289.3 million in collaborative arrangements revenue related to U.S. LINZESS sales. Its business is organized around its GI and rare-disease products and development programs, rather than reportable operating segments. Ironwood acquired VectivBio in 2023, adding apraglutide to its pipeline. Its website is www.ironwoodpharma.com.

Company details
Sector
Health Care
Industry (SIC)
Pharmaceutical Preparations
Headquarters
BOSTON, MA
Fiscal year end
December
CIK
1446847
SIC
2834

Financial performance, year by year

Fiscal 2011–2025 · USD
$-1.19B$-719.56M$-251.56M$216.45M$684.45M201120122013201420152016201720182019202020212022202320242025Last 12 moLast 12 monthsLast 12 months

The full income statement, balance sheet and cash flow for each of these years — every figure traceable to its filing — is on the Financials tab with a free account.

Ownership

Who owns Ironwood Pharmaceuticals, Inc. — and what changed

Funds as of 2026Q2 · superinvestors as of 2026-06-30

203
funds hold it
0 of 35
superinvestors hold it
$205.99M
held by funds, at market
30.5%
of shares held by funds

Largest fund holders · Ironwood Pharmaceuticals, Inc.’s weight in each

0.22%of fund net assets
VANGUARD TOTAL STOCK MARKET INDEX FUND
VTI · VANGUARD INDEX FUNDS
0.00%of fund net assets
iShares Russell 2000 ETF
IWM · iShares Trust
0.02%of fund net assets
Schwab Fundamental U.S. Small Company ETF
FNDA · SCHWAB STRATEGIC TRUST
—of fund net assets
VANGUARD STRATEGIC EQUITY FUND
VSEQX · VANGUARD HORIZON FUNDS
0.06%of fund net assets

Fund ownership is a floor, not a census — pensions, insurers and people holding shares directly are not visible here.

Fund ownership counts N-PORT filers only, so it is a floor rather than a census — pensions, insurers and direct holders are not visible here, and the remainder is not “held by individuals”.

Every fund and institutional holder, quarter by quarter, is on the Ownership tab with a free account.

Connected research

Put this business in context.

Compare this company with peers, find it in your funds and follow its financial history with your connected AI:

  • “How do Ironwood Pharmaceuticals, Inc. and its peers compare on margins and cash generation over ten years?”
  • “Where did five years of Ironwood Pharmaceuticals, Inc.'s earnings go — cash, debt, buybacks, reinvestment?”
  • “What changed in Ironwood Pharmaceuticals, Inc.'s last four quarterly filings that the numbers alone won't show?”
See how it works →All research tools with a subscription. Use your own AI account.