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Companies / Health Care / Jazz Pharmaceuticals plc
JAZZ

Jazz Pharmaceuticals plc

Health CarePharmaceutical Preparations
Ticker JAZZDUBLINFiscal year ends DecemberBook value per share $70.82Diluted shares 67.8M

Jazz Pharmaceuticals plc (Nasdaq: JAZZ) is a global biopharmaceutical company that develops and commercializes medicines, with a focus on rare diseases and patients with limited or no treatment options. Its portfolio includes therapies for sleep disorders, rare epilepsies and cancers, serving patients through… From the company’s description.

In fiscal 2025, Jazz Pharmaceuticals plc reported revenue of $4.27B, up 4.9% from fiscal 2024, and a net loss of $356.15M. Its operating margin was −10.1%, and operations generated $1.36B in cash. Over the twelve months to Jun 30, 2026, revenue was $4.60B.

Fiscal year 2025 · ends 12-31Changes are against fiscal 2024The amber dot is the latest twelve months, to 2026-06-30
Sales & profitability
$4.27BFY2025
+4.9% year over year
Last 12 mo $4.60B
-10.08%FY2025
−27.7 percentage points
Last 12 mo 19.49%
$-356.15MFY2025
−163.6% year over year
Last 12 mo $940.76M
-8.25%FY2025
−21.9 percentage points
Last 12 mo 19.59%
Cash & financing
$1.36BFY2025
−2.9% year over year
Last 12 mo $1.66B
$1.30BFY2025
−4.5% year over year
Last 12 mo $1.51B
1.24FY2025
Was 1.49× a year earlier
Last 12 mo 0.91
61.0MFY2025
−7.6% year over year
Last 12 mo 67.8M

Margins and return on equity change in ; everything else in percent. Fewer shares and less debt are shown plainly, not as bad news — it depends what you make of buybacks. Dotted labels explain each measure. is shown separately from the annual figures.

What Jazz Pharmaceuticals plc does

In the company’s own words

Jazz Pharmaceuticals plc (Nasdaq: JAZZ) is a global biopharmaceutical company that develops and commercializes medicines, with a focus on rare diseases and patients with limited or no treatment options. Its portfolio includes therapies for sleep disorders, rare epilepsies and cancers, serving patients through healthcare professionals and healthcare systems in the United States and international markets. Major products include Xywav and Xyrem for narcolepsy, Xywav for idiopathic hypersomnia, Epidiolex (marketed as Epidyolex in many countries outside the United States) for seizures associated with rare epilepsies, and the oncology medicines Zepzelca, Rylaze, Ziihera and Modeyso. The company also has research and development programs in rare diseases. Jazz acquired GW Pharmaceuticals in 2021, adding Epidiolex to its portfolio, and acquired Chimerix in 2025, adding Modeyso. Xywav generated $1.657 billion in net product sales in fiscal 2025.

Company details
Sector
Health Care
Industry (SIC)
Pharmaceutical Preparations
Headquarters
DUBLIN
Fiscal year end
December
CIK
1232524
SIC
2834

Financial performance, year by year

Fiscal 2013–2025 · USD
$-851.89M$635.33M$2.12B$3.61B$5.10B2013201420152016201720182019202020212022202320242025Last 12 moLast 12 monthsLast 12 months

The full income statement, balance sheet and cash flow for each of these years — every figure traceable to its filing — is on the Financials tab with a free account.

Ownership

Who owns Jazz Pharmaceuticals plc — and what changed

Funds as of 2026Q2 · superinvestors as of 2026-06-30

206
funds hold it
2 of 35
superinvestors hold it
$2.66B
held by funds, at market
17.4%
of shares held by funds

Superinvestors in Jazz Pharmaceuticals plc · what they did last quarter

Tweedy BrowneDECREASED -0.1%
Tweedy, Browne
1.1%of 13F portfolio
Polen CapitalNEW
Polen Capital Management
<0.1%of 13F portfolio

Share of each manager’s reported 13F portfolio. Change is in shares held, since the previous quarter.

Largest fund holders · Jazz Pharmaceuticals plc’s weight in each

VANGUARD TOTAL STOCK MARKET INDEX FUND
VTI · VANGUARD INDEX FUNDS
0.02%of fund net assets
FULLERTHALER BEHAVIORAL SMALL CAP EQUITY
FTHNX · Capitol Series Trust
2.97%of fund net assets
VANGUARD SMALL-CAP INDEX FUND
VB · VANGUARD INDEX FUNDS
0.17%of fund net assets
VANGUARD SMALL-CAP VALUE INDEX FUND
VBR · VANGUARD INDEX FUNDS
0.31%of fund net assets
VANGUARD EXTENDED MARKET INDEX FUND
VXF · VANGUARD INDEX FUNDS
0.18%of fund net assets

Fund ownership is a floor, not a census — pensions, insurers and people holding shares directly are not visible here.

Fund ownership counts N-PORT filers only, so it is a floor rather than a census — pensions, insurers and direct holders are not visible here, and the remainder is not “held by individuals”.

Fund ownership is a subset of institutional 13F ownership — the two describe overlapping populations and must not be added together.

Could not be determined for this company: bond issues.

Every fund and institutional holder, quarter by quarter, is on the Ownership tab with a free account.

Connected research

Put this business in context.

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  • “How do Jazz Pharmaceuticals plc and its peers compare on margins and cash generation over ten years?”
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